Proto-Oncogene Proteins c-crk
"Proto-Oncogene Proteins c-crk" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Signal transducing adaptor proteins that contain SRC HOMOLOGY DOMAINS and play a role in CYTOSKELETON reorganization. c-crk protein is closely related to ONCOGENE PROTEIN V-CRK and includes several alternatively spliced isoforms.
| Descriptor ID |
D050737
|
| MeSH Number(s) |
D12.644.360.024.320 D12.776.157.057.139 D12.776.476.024.404 D12.776.624.664.700.174
|
| Concept/Terms |
Proto-Oncogene Proteins c-crk- Proto-Oncogene Proteins c-crk
- Proteins c-crk, Proto-Oncogene
- Proto Oncogene Proteins c crk
- c-crk, Proto-Oncogene Proteins
- Proto-Oncogene Protein c-crk
- Proto Oncogene Protein c crk
- c-crk, Proto-Oncogene Protein
- crk Proto-Oncogene Proteins
- Proto-Oncogene Proteins, crk
- crk Proto Oncogene Proteins
- c-crk Proto-Oncogene Proteins
- Proto-Oncogene Proteins, c-crk
- c crk Proto Oncogene Proteins
- c-crk Protein
- CT10 Regulator of Kinase Protein
Proto-Oncogene Protein c-crk-2- Proto-Oncogene Protein c-crk-2
- Proto Oncogene Protein c crk 2
- c-crk-2, Proto-Oncogene Protein
- CRKII Protein
- c-crk-2 Proto-Oncogene Protein
- Proto-Oncogene Protein, c-crk-2
- c crk 2 Proto Oncogene Protein
- Crk-2 Protein
- Crk 2 Protein
- CrkII Adapter Protein
- Adapter Protein, CrkII
- c-CrkII Protein
- c CrkII Protein
Proto-Oncogene Protein c-crk-3- Proto-Oncogene Protein c-crk-3
- Proto Oncogene Protein c crk 3
- c-crk-3, Proto-Oncogene Protein
- CrkIII Protein
- c-crk-3 Proto-Oncogene Protein
- Proto-Oncogene Protein, c-crk-3
- c crk 3 Proto Oncogene Protein
- c-CrkIII Protein
- c CrkIII Protein
- Crk3 Protein
Proto-Oncogene Protein c-crk-1- Proto-Oncogene Protein c-crk-1
- Proto Oncogene Protein c crk 1
- c-crk-1, Proto-Oncogene Protein
- CRKI Protein
- c-crk-I Proto-Oncogene Protein
- Proto-Oncogene Protein, c-crk-I
- c crk I Proto Oncogene Protein
- Crk-1 Protein
- Crk 1 Protein
- c-crkI Protein
|
Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins c-crk".
Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins c-crk".
This graph shows the total number of publications written about "Proto-Oncogene Proteins c-crk" by people in this website by year, and whether "Proto-Oncogene Proteins c-crk" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Proto-Oncogene Proteins c-crk" by people in Profiles.
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Crk and Crkl have shared functions in neural crest cells for cardiac outflow tract septation and vascular smooth muscle differentiation. Hum Mol Genet. 2022 04 22; 31(8):1197-1215.
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Cell shape-based chemical screening reveals an epigenetic network mediated by focal adhesions. FEBS J. 2021 10; 288(19):5613-5628.
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Essential role of the Crk family-dosage in DiGeorge-like anomaly and metabolic homeostasis. Life Sci Alliance. 2020 02; 3(2).
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Mutations in the NS1 C-terminal tail do not enhance replication or virulence of the 2009 pandemic H1N1 influenza A virus. J Gen Virol. 2010 Jul; 91(Pt 7):1737-42.
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Structural and functional basis of a role for CRKL in a fibroblast growth factor 8-induced feed-forward loop. Mol Cell Biol. 2009 Jun; 29(11):3076-87.
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Crkl deficiency disrupts Fgf8 signaling in a mouse model of 22q11 deletion syndromes. Dev Cell. 2006 Jan; 10(1):71-80.
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CrkL and CrkII participate in the generation of the growth inhibitory effects of interferons on primary hematopoietic progenitors. Exp Hematol. 1999 Aug; 27(8):1315-21.
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Crk protein binds to PDGF receptor and insulin receptor substrate-1 with different modulating effects on PDGF- and insulin-dependent signaling pathways. Oncogene. 1998 May 14; 16(19):2425-34.
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The BCR/ABL oncogene alters interaction of the adapter proteins CRKL and CRK with cellular proteins. Leukemia. 1997 Mar; 11(3):376-85.
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The proto-oncogene product p120CBL and the adaptor proteins CRKL and c-CRK link c-ABL, p190BCR/ABL and p210BCR/ABL to the phosphatidylinositol-3' kinase pathway. Oncogene. 1996 Feb 15; 12(4):839-46.