"Loperamide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
| Descriptor ID |
D008139
|
| MeSH Number(s) |
D03.383.621.440
|
| Concept/Terms |
Loperamide Hydrochloride- Loperamide Hydrochloride
- Hydrochloride, Loperamide
- Loperamide Monohydrochloride
- Monohydrochloride, Loperamide
|
Below are MeSH descriptors whose meaning is more general than "Loperamide".
Below are MeSH descriptors whose meaning is more specific than "Loperamide".
This graph shows the total number of publications written about "Loperamide" by people in this website by year, and whether "Loperamide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 2 | 1 | 3 |
| 2008 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Loperamide" by people in Profiles.
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Mutual reinforcement of pathophysiological host-microbe interactions in intestinal stasis models. Physiol Rep. 2017 Mar; 5(6).
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The role of loperamide in gastrointestinal disorders. Rev Gastroenterol Disord. 2008; 8(1):15-20.
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Randomized, double-blind, placebo-controlled clinical trial of loperamide plus simethicone versus loperamide alone and simethicone alone in the treatment of acute diarrhea with gas-related abdominal discomfort. Curr Med Res Opin. 2007 May; 23(5):1033-43.
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Treatment of diarrhea in patients with inflammatory bowel disease: concepts and cautions. Rev Gastroenterol Disord. 2007; 7 Suppl 3:S3-10.
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The benefits of loperamide in the treatment of patients with IBS or IBD. Introduction. Rev Gastroenterol Disord. 2007; 7 Suppl 3:S1-2.
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Secretagogue-induced changes in membrane calcium permeability in chicken and chinchilla ileal mucosa. Selective inhibition by loperamide. J Clin Invest. 1986 Jul; 78(1):281-7.