Blockade of T cell activation using a surface-linked single-chain antibody to CTLA-4 (CD152).
Griffin MD, Hong DK, Holman PO, Lee KM, Whitters MJ, O'Herrin SM, Fallarino F, Collins M, Segal DM, Gajewski TF, Kranz DM, Bluestone JA. Blockade of T cell activation using a surface-linked single-chain antibody to CTLA-4 (CD152). J Immunol. 2000 May 01; 164(9):4433-42.
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Amino Acid Sequence
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Animals
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Antibodies, Blocking
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Antibody Specificity
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Antigens, CD
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Antigens, Differentiation
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CD4-Positive T-Lymphocytes
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CD8-Positive T-Lymphocytes
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Cell Line
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CTLA-4 Antigen
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Cytokines
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Female
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Humans
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Immunoconjugates
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Immunoglobulin Variable Region
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Interphase
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Ligands
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Lymphocyte Activation
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Major Histocompatibility Complex
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Mice
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Mice, Inbred BALB C
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Mice, Transgenic
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Molecular Sequence Data
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Peptides
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Receptors, Antigen, B-Cell
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Receptors, Antigen, T-Cell
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Signal Transduction
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T-Lymphocyte Subsets
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Transfection
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Tumor Cells, Cultured