"Second Messenger Systems" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Systems in which an intracellular signal is generated in response to an intercellular primary messenger such as a hormone or neurotransmitter. They are intermediate signals in cellular processes such as metabolism, secretion, contraction, phototransduction, and cell growth. Examples of second messenger systems are the adenyl cyclase-cyclic AMP system, the phosphatidylinositol diphosphate-inositol triphosphate system, and the cyclic GMP system.
Descriptor ID |
D015290
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MeSH Number(s) |
G02.111.820.800 G04.835.800
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Concept/Terms |
Second Messenger Systems- Second Messenger Systems
- Second Messenger System
- System, Second Messenger
- Systems, Second Messenger
- Intracellular Second Messengers
- Intracellular Second Messenger
- Messengers, Intracellular Second
- Second Messenger, Intracellular
- Second Messengers, Intracellular
Second Messengers- Second Messengers
- Messenger, Second
- Messengers, Second
- Second Messenger
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Below are MeSH descriptors whose meaning is more general than "Second Messenger Systems".
Below are MeSH descriptors whose meaning is more specific than "Second Messenger Systems".
This graph shows the total number of publications written about "Second Messenger Systems" by people in this website by year, and whether "Second Messenger Systems" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1994 | 1 | 0 | 1 |
1995 | 0 | 1 | 1 |
1996 | 1 | 0 | 1 |
1998 | 0 | 2 | 2 |
1999 | 0 | 3 | 3 |
2002 | 0 | 2 | 2 |
2004 | 0 | 1 | 1 |
2005 | 1 | 0 | 1 |
2007 | 1 | 0 | 1 |
2008 | 1 | 0 | 1 |
2009 | 0 | 1 | 1 |
2011 | 1 | 0 | 1 |
2012 | 1 | 0 | 1 |
2013 | 2 | 0 | 2 |
2015 | 1 | 1 | 2 |
2016 | 1 | 0 | 1 |
2017 | 0 | 2 | 2 |
2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Second Messenger Systems" by people in Profiles.
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Controlled release of bioactive signaling molecules. Methods Enzymol. 2020; 638:129-138.
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Stability analysis in spatial modeling of cell signaling. Wiley Interdiscip Rev Syst Biol Med. 2018 01; 10(1).
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Investigations of human myosin VI targeting using optogenetically controlled cargo loading. Proc Natl Acad Sci U S A. 2017 02 28; 114(9):E1607-E1616.
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Pancreatic Beta Cell G-Protein Coupled Receptors and Second Messenger Interactions: A Systems Biology Computational Analysis. PLoS One. 2016; 11(5):e0152869.
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The translational regulator Cup controls NMJ presynaptic terminal morphology. Mol Cell Neurosci. 2015 Jul; 67:126-36.
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International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors. Pharmacol Rev. 2015; 67(2):338-67.
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Achieving "PeaK-A" insulin secretion. Diabetes. 2013 May; 62(5):1389-90.
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ß-Cell-specific protein kinase A activation enhances the efficiency of glucose control by increasing acute-phase insulin secretion. Diabetes. 2013 May; 62(5):1527-36.
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Gaseous messengers in oxygen sensing. J Mol Med (Berl). 2012 Mar; 90(3):265-72.
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Coupling of metabolic, second messenger pathways and insulin granule dynamics in pancreatic beta-cells: a computational analysis. Prog Biophys Mol Biol. 2011 Nov; 107(2):293-303.