"Mice, Obese" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Mutant mice exhibiting a marked obesity coupled with overeating, hyperglycemia, hyperinsulinemia, marked insulin resistance, and infertility when in a homozygous state. They may be inbred or hybrid.
- Mice, Obese
- Mouse, Obese
- Obese Mouse
- Obese Mice
Below are MeSH descriptors whose meaning is more general than "Mice, Obese".
Below are MeSH descriptors whose meaning is more specific than "Mice, Obese".
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Below are the most recent publications written about "Mice, Obese" by people in Profiles.
Effects of Vitamin D Supplementation on Adipose Tissue Inflammation and NF-?B/AMPK Activation in Obese Mice Fed a High-Fat Diet. Int J Mol Sci. 2022 Sep 18; 23(18).
An Iron Refractory Phenotype in Obese Adipose Tissue Macrophages Leads to Adipocyte Iron Overload. Int J Mol Sci. 2022 Jul 03; 23(13).
Peptide-YY3-36/glucagon-like peptide-1 combination treatment of obese diabetic mice improves insulin sensitivity associated with recovered pancreatic ?-cell function and synergistic activation of discrete hypothalamic and brainstem neuronal circuitries. Mol Metab. 2022 01; 55:101392.
Restored TDCA and valine levels imitate the effects of bariatric surgery. Elife. 2021 06 22; 10.
Control of hyperglycemia in male mice by leflunomide: mechanisms of action. J Endocrinol. 2018 04; 237(1):43-58.
Phenotypic assays identify azoramide as a small-molecule modulator of the unfolded protein response with antidiabetic activity. Sci Transl Med. 2015 Jun 17; 7(292):292ra98.
Impaired clearance of influenza A virus in obese, leptin receptor deficient mice is independent of leptin signaling in the lung epithelium and macrophages. PLoS One. 2014; 9(9):e108138.
Metabolic dysfunction drives a mechanistically distinct proinflammatory phenotype in adipose tissue macrophages. Cell Metab. 2014 Oct 07; 20(4):614-25.
Fas (CD95) expression in myeloid cells promotes obesity-induced muscle insulin resistance. EMBO Mol Med. 2014 01; 6(1):43-56.
Thrombospondin-1 induction in the diabetic myocardium stabilizes the cardiac matrix in addition to promoting vascular rarefaction through angiopoietin-2 upregulation. Circ Res. 2013 Dec 06; 113(12):1331-44.