"Mice, Obese" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Mutant mice exhibiting a marked obesity coupled with overeating, hyperglycemia, hyperinsulinemia, marked insulin resistance, and infertility when in a homozygous state. They may be inbred or hybrid.
| Descriptor ID |
D008820
|
| MeSH Number(s) |
B01.050.150.900.649.313.992.635.505.500.550.530
|
| Concept/Terms |
Mice, Obese- Mice, Obese
- Mouse, Obese
- Obese Mouse
- Obese Mice
|
Below are MeSH descriptors whose meaning is more general than "Mice, Obese".
Below are MeSH descriptors whose meaning is more specific than "Mice, Obese".
This graph shows the total number of publications written about "Mice, Obese" by people in this website by year, and whether "Mice, Obese" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 3 | 3 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 4 | 4 |
| 2010 | 0 | 4 | 4 |
| 2011 | 0 | 1 | 1 |
| 2013 | 0 | 2 | 2 |
| 2014 | 0 | 3 | 3 |
| 2021 | 0 | 2 | 2 |
| 2022 | 0 | 2 | 2 |
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Below are the most recent publications written about "Mice, Obese" by people in Profiles.
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Effects of Vitamin D Supplementation on Adipose Tissue Inflammation and NF-?B/AMPK Activation in Obese Mice Fed a High-Fat Diet. Int J Mol Sci. 2022 Sep 18; 23(18).
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An Iron Refractory Phenotype in Obese Adipose Tissue Macrophages Leads to Adipocyte Iron Overload. Int J Mol Sci. 2022 Jul 03; 23(13).
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Peptide-YY3-36/glucagon-like peptide-1 combination treatment of obese diabetic mice improves insulin sensitivity associated with recovered pancreatic ?-cell function and synergistic activation of discrete hypothalamic and brainstem neuronal circuitries. Mol Metab. 2022 01; 55:101392.
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Restored TDCA and valine levels imitate the effects of bariatric surgery. Elife. 2021 06 22; 10.
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Control of hyperglycemia in male mice by leflunomide: mechanisms of action. J Endocrinol. 2018 04; 237(1):43-58.
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Phenotypic assays identify azoramide as a small-molecule modulator of the unfolded protein response with antidiabetic activity. Sci Transl Med. 2015 Jun 17; 7(292):292ra98.
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Impaired clearance of influenza A virus in obese, leptin receptor deficient mice is independent of leptin signaling in the lung epithelium and macrophages. PLoS One. 2014; 9(9):e108138.
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Metabolic dysfunction drives a mechanistically distinct proinflammatory phenotype in adipose tissue macrophages. Cell Metab. 2014 Oct 07; 20(4):614-25.
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Fas (CD95) expression in myeloid cells promotes obesity-induced muscle insulin resistance. EMBO Mol Med. 2014 01; 6(1):43-56.
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Thrombospondin-1 induction in the diabetic myocardium stabilizes the cardiac matrix in addition to promoting vascular rarefaction through angiopoietin-2 upregulation. Circ Res. 2013 Dec 06; 113(12):1331-44.