"Integrin alpha6" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An integrin alpha subunit that primarily associates with INTEGRIN BETA1 or INTEGRIN BETA4 to form laminin-binding heterodimers. Integrin alpha6 has two alternatively spliced isoforms: integrin alpha6A and integrin alpha6B, which differ in their cytoplasmic domains and are regulated in a tissue-specific and developmental stage-specific manner.
| Descriptor ID |
D039503
|
| MeSH Number(s) |
D12.776.543.750.705.408.100.550
|
| Concept/Terms |
Integrin alpha6- Integrin alpha6
- alpha6, Integrin
- CD49f Antigens
- alpha6 Integrin
- Integrin, alpha6
- Antigens, CD49f
- CD49f Antigen
- Antigen, CD49f
- alpha(6) Integrin
|
Below are MeSH descriptors whose meaning is more general than "Integrin alpha6".
Below are MeSH descriptors whose meaning is more specific than "Integrin alpha6".
This graph shows the total number of publications written about "Integrin alpha6" by people in this website by year, and whether "Integrin alpha6" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Integrin alpha6" by people in Profiles.
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Breast cancer exploits neural signaling pathways for bone-to-meninges metastasis. Science. 2024 Jun 21; 384(6702):eadh5548.
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Leukaemia hijacks a neural mechanism to invade the central nervous system. Nature. 2018 08; 560(7716):55-60.
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AhR ligand Aminoflavone inhibits a6-integrin expression and breast cancer sphere-initiating capacity. Cancer Lett. 2016 06 28; 376(1):53-61.
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CD49f and CD61 identify Her2/neu-induced mammary tumor-initiating cells that are potentially derived from luminal progenitors and maintained by the integrin-TGFß signaling. Oncogene. 2012 May 24; 31(21):2614-26.