"Integrin alphaV" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alpha integrin with a molecular weight of 160-kDa that is found in a variety of cell types. It undergoes posttranslational cleavage into a heavy and a light chain that are connected by disulfide bonds. Integrin alphaV can combine with several different beta subunits to form heterodimers that generally bind to RGD sequence-containing extracellular matrix proteins.
| Descriptor ID |
D039564
|
| MeSH Number(s) |
D12.776.543.750.705.408.100.900
|
| Concept/Terms |
Integrin alphaV- Integrin alphaV
- alphaV, Integrin
- alpha(V) Integrin
- Integrin alpha V
- alpha V, Integrin
- CD51 Antigens
- alphav Integrin
- Integrin, alphav
- Antigens, CD51
- CD51 Antigen
- Antigen, CD51
|
Below are MeSH descriptors whose meaning is more general than "Integrin alphaV".
Below are MeSH descriptors whose meaning is more specific than "Integrin alphaV".
This graph shows the total number of publications written about "Integrin alphaV" by people in this website by year, and whether "Integrin alphaV" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Integrin alphaV" by people in Profiles.
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Inhibition of Cancer Cell Adhesion, Migration and Proliferation by a Bispecific Antibody that Targets two Distinct Epitopes on av Integrins. J Mol Biol. 2021 07 23; 433(15):167090.
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Characterization of Nestin-positive stem Leydig cells as a potential source for the treatment of testicular Leydig cell dysfunction. Cell Res. 2014 Dec; 24(12):1466-85.
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aV-integrins are required for mechanotransduction in MDCK epithelial cells. PLoS One. 2013; 8(8):e71485.
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The motogenic effects of cyclic mechanical strain on intestinal epithelial monolayer wound closure are matrix dependent. Gastroenterology. 2006 Oct; 131(4):1179-89.
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Glioblastoma cells block radiation-induced programmed cell death of endothelial cells. FEBS Lett. 2004 May 07; 565(1-3):167-70.