"CD11c Antigen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An integrin alpha subunit of approximately 150-kDa molecular weight. It is expressed at high levels on monocytes and combines with CD18 ANTIGEN to form the cell surface receptor INTEGRIN ALPHAXBETA2. The subunit contains a conserved I-domain which is characteristic of several of alpha integrins.
| Descriptor ID |
D039521
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| MeSH Number(s) |
D12.776.395.550.200.074.875 D12.776.395.550.200.275.500 D12.776.543.550.200.093.875 D12.776.543.550.200.275.500 D12.776.543.750.705.408.100.200 D12.776.543.750.705.408.600.100.500 D12.776.543.750.705.833.249.500 D23.050.301.350.074.074 D23.050.301.350.275.500
|
| Concept/Terms |
CD11c Antigen- CD11c Antigen
- Antigen, CD11c
- Antigens, CD11c
- CD11c Antigens
- Integrin alphaX
- alphaX, Integrin
- Leu-M5 Antigens
- Antigens, Leu-M5
- Leu M5 Antigens
|
Below are MeSH descriptors whose meaning is more general than "CD11c Antigen".
Below are MeSH descriptors whose meaning is more specific than "CD11c Antigen".
This graph shows the total number of publications written about "CD11c Antigen" by people in this website by year, and whether "CD11c Antigen" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 1 | 2 |
| 2007 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 1 | 2 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
| 2024 | 2 | 0 | 2 |
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Below are the most recent publications written about "CD11c Antigen" by people in Profiles.
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Nuclear Factor ?B Signaling Deficiency in CD11c-Expressing Phagocytes Mediates Early Inflammatory Responses and Enhances Mycobacterium tuberculosis Control. J Infect Dis. 2024 Aug 16; 230(2):336-345.
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PIKfyve, expressed by CD11c-positive cells, controls tumor immunity. Nat Commun. 2024 Jun 28; 15(1):5487.
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CD11c+CD163+ Cells and Signal Transducer and Activator of Transcription 3 (STAT3) Expression Are Common in Melanoma Leptomeningeal Disease. Front Immunol. 2021; 12:745893.
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Clinical significance of T cell clonality and expression levels of immune-related genes in endometrial cancer. Oncol Rep. 2017 May; 37(5):2603-2610.
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TLR-7 activation enhances IL-22-mediated colonization resistance against vancomycin-resistant enterococcus. Sci Transl Med. 2016 Feb 24; 8(327):327ra25.
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Chronic myelomonocytic leukemia monocytes uniformly display a population of monocytes with CD11c underexpression. Am J Clin Pathol. 2013 Nov; 140(5):686-92.
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Separation of plasmacytoid dendritic cells from B-cell-biased lymphoid progenitor (BLP) and Pre-pro B cells using PDCA-1. PLoS One. 2013; 8(10):e78408.
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PCOS is associated with increased CD11c expression and crown-like structures in adipose tissue and increased central abdominal fat depots independent of obesity. J Clin Endocrinol Metab. 2013 Jan; 98(1):E17-24.
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Elimination of antigen-presenting cells and autoreactive T cells by Fas contributes to prevention of autoimmunity. Immunity. 2007 May; 26(5):629-41.
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In vivo expansion of two distinct dendritic cells in mouse livers and its impact on liver immune regulation. Liver Transpl. 2006 Dec; 12(12):1850-61.