Interferon Regulatory Factor-1
"Interferon Regulatory Factor-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An interferon regulatory factor that binds upstream TRANSCRIPTIONAL REGULATORY ELEMENTS in the GENES for INTERFERON-ALPHA and INTERFERON-BETA. It functions as a transcriptional activator for the INTERFERON TYPE I genes.
| Descriptor ID |
D050856
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| MeSH Number(s) |
D12.644.360.024.302.124 D12.776.157.057.050.124 D12.776.260.108.374 D12.776.260.504.124 D12.776.476.024.385.124 D12.776.930.127.374 D12.776.930.332.124
|
| Concept/Terms |
Interferon Regulatory Factor-1- Interferon Regulatory Factor-1
- Interferon Regulatory Factor 1
- IRF-1 Protein
- IRF 1 Protein
- IREBF1 Transcription Factor
- Transcription Factor, IREBF1
- IREBF1 Protein
- IRF-1 Transcription Factor
- Factor, IRF-1 Transcription
- IRF 1 Transcription Factor
- Transcription Factor, IRF-1
- ISGF1 Transcription Factor
- Factor, ISGF1 Transcription
- Transcription Factor, ISGF1
- Interferon-Stimulated Gene Factor 1
- Interferon Stimulated Gene Factor 1
- MyD32 Protein
|
Below are MeSH descriptors whose meaning is more general than "Interferon Regulatory Factor-1".
Below are MeSH descriptors whose meaning is more specific than "Interferon Regulatory Factor-1".
This graph shows the total number of publications written about "Interferon Regulatory Factor-1" by people in this website by year, and whether "Interferon Regulatory Factor-1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 1 | 2 |
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Below are the most recent publications written about "Interferon Regulatory Factor-1" by people in Profiles.
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Anhedonia in cocaine use disorder is associated with inflammatory gene expression. PLoS One. 2018; 13(11):e0207231.
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Murine Norovirus Infection Induces TH1 Inflammatory Responses to Dietary Antigens. Cell Host Microbe. 2018 11 14; 24(5):677-688.e5.
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Reovirus infection triggers inflammatory responses to dietary antigens and development of celiac disease. Science. 2017 04 07; 356(6333):44-50.
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The macrophage IRF8/IRF1 regulome is required for protection against infections and is associated with chronic inflammation. J Exp Med. 2016 Apr 04; 213(4):585-603.
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Peripheral blood IRF1 expression as a marker for glucocorticoid sensitivity. Pharmacogenet Genomics. 2015 Mar; 25(3):126-33.
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Inhibition of interferon-beta responses in multiple sclerosis immune cells associated with high-dose statins. Arch Neurol. 2012 Oct; 69(10):1303-9.
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Essential cell-autonomous role for interferon (IFN) regulatory factor 1 in IFN-?-mediated inhibition of norovirus replication in macrophages. J Virol. 2012 Dec; 86(23):12655-64.
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Long-term suppression of tumor growth by TNF requires a Stat1- and IFN regulatory factor 1-dependent IFN-gamma pathway but not IL-12 or IL-18. J Immunol. 2004 Mar 01; 172(5):3243-51.
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Interferon-gamma-induced inhibition of neuronal vesicular stomatitis virus infection is STAT1 dependent. J Neurovirol. 2004 Feb; 10(1):57-63.
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Murine natural killer cell progenitors and their requirements for development. Semin Immunol. 2002 Dec; 14(6):453-60.