Interferon Regulatory Factor-7
"Interferon Regulatory Factor-7" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An interferon regulatory factor that is induced by INTERFERONS as well as LMP-1 protein from EPSTEIN-BARR VIRUS. IRF-7 undergoes PHOSPHORYLATION prior to nuclear translocation and it activates GENETIC TRANSCRIPTION of multiple interferon GENES.
| Descriptor ID |
D050839
|
| MeSH Number(s) |
D12.644.360.024.302.437 D12.776.157.057.050.437 D12.776.260.504.437 D12.776.476.024.385.437 D12.776.744.631 D12.776.930.332.437
|
| Concept/Terms |
IRF-7C Transcription Factor- IRF-7C Transcription Factor
- Factor, IRF-7C Transcription
- IRF 7C Transcription Factor
- Transcription Factor, IRF-7C
|
Below are MeSH descriptors whose meaning is more general than "Interferon Regulatory Factor-7".
Below are MeSH descriptors whose meaning is more specific than "Interferon Regulatory Factor-7".
This graph shows the total number of publications written about "Interferon Regulatory Factor-7" by people in this website by year, and whether "Interferon Regulatory Factor-7" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Interferon Regulatory Factor-7" by people in Profiles.
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Activation of type I interferon signaling in the parotid and exorbital lachrymal glands during the acute phase of encephalomyocarditis (EMC) virus infection in mice. Exp Mol Pathol. 2016 06; 100(3):434-40.
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GADD45a promoter regulation by a functional genetic variant associated with acute lung injury. PLoS One. 2014; 9(6):e100169.
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Common genetic variants modulate pathogen-sensing responses in human dendritic cells. Science. 2014 Mar 07; 343(6175):1246980.
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Use of IRF-3 and/or IRF-7 knockout mice to study viral pathogenesis: lessons from a murine retrovirus-induced AIDS model. J Virol. 2014 Feb; 88(4):2349-53.
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IRF7-dependent IFN-ß production in response to RANKL promotes medullary thymic epithelial cell development. J Immunol. 2013 Apr 01; 190(7):3289-98.
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Genetic variation at the IRF7/PHRF1 locus is associated with autoantibody profile and serum interferon-alpha activity in lupus patients. Arthritis Rheum. 2010 Feb; 62(2):553-61.
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Inhibition of interferon regulatory factor 7 (IRF7)-mediated interferon signal transduction by the Kaposi's sarcoma-associated herpesvirus viral IRF homolog vIRF3. J Virol. 2007 Aug; 81(15):8282-92.