"Genes, myc" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Family of retrovirus-associated DNA sequences (myc) originally isolated from an avian myelocytomatosis virus. The proto-oncogene myc (c-myc) codes for a nuclear protein which is involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Truncation of the first exon, which appears to regulate c-myc expression, is crucial for tumorigenicity. The human c-myc gene is located at 8q24 on the long arm of chromosome 8.
| Descriptor ID |
D016259
|
| MeSH Number(s) |
G05.360.340.024.340.375.500.791.420
|
| Concept/Terms |
c-myc Genes- c-myc Genes
- Gene, c-myc
- Genes, c-myc
- c myc Genes
- c-myc Gene
c-myc Proto-Oncogenes- c-myc Proto-Oncogenes
- Proto-Oncogene, c-myc
- Proto-Oncogenes, c-myc
- c myc Proto Oncogenes
- c-myc Proto-Oncogene
v-myc Genes- v-myc Genes
- Gene, v-myc
- Genes, v-myc
- v myc Genes
- v-myc Gene
L-myc Proto-Oncogenes- L-myc Proto-Oncogenes
- L myc Proto Oncogenes
- L-myc Proto-Oncogene
- Proto-Oncogene, L-myc
- Proto-Oncogenes, L-myc
myc Oncogene- myc Oncogene
- Oncogene, myc
- Oncogenes, myc
- myc Oncogenes
N-myc Genes- N-myc Genes
- Gene, N-myc
- Genes, N-myc
- N myc Genes
- N-myc Gene
N-myc Proto-Oncogenes- N-myc Proto-Oncogenes
- N myc Proto Oncogenes
- N-myc Proto-Oncogene
- Proto-Oncogene, N-myc
- Proto-Oncogenes, N-myc
v-myc Oncogenes- v-myc Oncogenes
- Oncogene, v-myc
- Oncogenes, v-myc
- v myc Oncogenes
- v-myc Oncogene
L-myc Genes- L-myc Genes
- Gene, L-myc
- Genes, L-myc
- L myc Genes
- L-myc Gene
|
Below are MeSH descriptors whose meaning is more general than "Genes, myc".
Below are MeSH descriptors whose meaning is more specific than "Genes, myc".
This graph shows the total number of publications written about "Genes, myc" by people in this website by year, and whether "Genes, myc" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1995 | 0 | 1 | 1 |
| 1997 | 1 | 0 | 1 |
| 1998 | 1 | 1 | 2 |
| 1999 | 0 | 1 | 1 |
| 2000 | 2 | 1 | 3 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 1 | 1 | 2 |
| 2009 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 2 | 3 |
| 2014 | 0 | 2 | 2 |
| 2015 | 1 | 2 | 3 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 2 | 3 |
| 2019 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Genes, myc" by people in Profiles.
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Identification of Novel RAS Signaling Therapeutic Vulnerabilities in Diffuse Intrinsic Pontine Gliomas. Cancer Res. 2019 08 15; 79(16):4026-4041.
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Differences in genomic abnormalities among African individuals with monoclonal gammopathies using calculated ancestry. Blood Cancer J. 2018 10 10; 8(10):96.
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A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies. Nature. 2018 01 25; 553(7689):515-520.
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Impact of oncogenic pathways on evasion of antitumour immune responses. Nat Rev Cancer. 2018 03; 18(3):139-147.
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A c-Myc-regulated stem cell-like signature in high-risk neuroblastoma: A systematic discovery (Target neuroblastoma ESC-like signature). Sci Rep. 2017 03 03; 7(1):41.
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Impact of oncogene rearrangement patterns on outcomes in patients with double-hit non-Hodgkin lymphoma. Cancer. 2016 Feb 15; 122(4):559-64.
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Butyrate inhibits pro-proliferative miR-92a by diminishing c-Myc-induced miR-17-92a cluster transcription in human colon cancer cells. Mol Cancer. 2015 Oct 13; 14:180.
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Augmented expression of MYC and/or MYCN protein defines highly aggressive MYC-driven neuroblastoma: a Children's Oncology Group study. Br J Cancer. 2015 Jun 30; 113(1):57-63.
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Telomerase regulates MYC-driven oncogenesis independent of its reverse transcriptase activity. J Clin Invest. 2015 May; 125(5):2109-22.
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Can vitamin D reduce the risk of uterine fibroids? Womens Health (Lond). 2014 Jul; 10(4):353-8.