"Lymphotoxin-beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A membrane-bound tumor necrosis family member found primarily on LYMPHOCYTES. It can form a heterotrimer (LYMPHOTOXIN ALPHA1, BETA2 HETEROTRIMER) with the soluble ligand LYMPHOTOXIN-ALPHA and anchor it to the cell surface. The membrane-bound complex is specific for the LYMPHOTOXIN BETA receptor.
| Descriptor ID |
D053308
|
| MeSH Number(s) |
D12.644.276.374.750.515 D12.776.467.374.750.515 D23.529.374.750.515
|
| Concept/Terms |
Lymphotoxin-beta- Lymphotoxin-beta
- Tumor Necrosis Factor Ligand Superfamily Member 3
- Tumor Necrosis Factor C
- Lymphotoxin beta
- beta, Lymphotoxin
- TNF Superfamily, Member 3
|
Below are MeSH descriptors whose meaning is more general than "Lymphotoxin-beta".
Below are MeSH descriptors whose meaning is more specific than "Lymphotoxin-beta".
This graph shows the total number of publications written about "Lymphotoxin-beta" by people in this website by year, and whether "Lymphotoxin-beta" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2006 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lymphotoxin-beta" by people in Profiles.
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Lymphotoxin organizes contributions to host defense and metabolic illness from innate lymphoid cells. Cytokine Growth Factor Rev. 2014 Apr; 25(2):227-33.
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Tissue damage-associated "danger signals" influence T-cell responses that promote the progression of preneoplasia to cancer. Cancer Res. 2013 Jan 15; 73(2):629-39.
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IgE regulates T helper cell differentiation through FcgammaRIII mediated dendritic cell cytokine modulation. Cell Immunol. 2010; 264(1):54-60.
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T cell-derived lymphotoxin regulates liver regeneration. Gastroenterology. 2009 Feb; 136(2):694-704.e4.
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Lymphotoxin pathway-directed, autoimmune regulator-independent central tolerance to arthritogenic collagen. J Immunol. 2006 Jul 01; 177(1):290-7.
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Membrane lymphotoxin is required for resistance to Theiler's virus infection. Int Immunol. 2003 Aug; 15(8):955-62.
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Expression of lymphotoxin-beta (LT-beta) in chronic inflammatory conditions. J Pathol. 2003 Jan; 199(1):115-21.
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Distinct role of surface lymphotoxin expressed by B cells in the organization of secondary lymphoid tissues. Immunity. 2002 Sep; 17(3):239-50.