"Mucin-4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transmembrane mucin that is found in a broad variety of epithelial tissue. Mucin-4 may play a role in regulating cellular adhesion and in cell surface signaling from the ERBB-2 RECEPTOR PROTEIN-TYROSINE KINASE. Mucin-4 is a heterodimer of alpha and beta chains. The alpha and beta chains result from the proteolytic cleavage of a precursor protein.
| Descriptor ID |
D055264
|
| MeSH Number(s) |
D12.644.360.534 D12.776.395.560.631.195 D12.776.476.534
|
| Concept/Terms |
Mucin-4 alpha chain- Mucin-4 alpha chain
- Mucin 4 alpha chain
- Ascites Sialoglycoprotein 1
- Sialoglycoprotein 1, Ascites
- ASGP-1
|
Below are MeSH descriptors whose meaning is more general than "Mucin-4".
Below are MeSH descriptors whose meaning is more specific than "Mucin-4".
This graph shows the total number of publications written about "Mucin-4" by people in this website by year, and whether "Mucin-4" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Mucin-4" by people in Profiles.
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MUC4 expression by immunohistochemistry is a specific marker for BCR-ABL1+ and BCR-ABL1-like B-lymphoblastic leukemia. Leuk Lymphoma. 2022 06; 63(6):1436-1444.
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Morphological Changes, Cadherin Switching, and Growth Suppression in Pancreatic Cancer by GALNT6 Knockdown. Neoplasia. 2016 05; 18(5):265-272.
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Mice deficient in Muc4 are resistant to experimental colitis and colitis-associated colorectal cancer. Oncogene. 2016 05 19; 35(20):2645-54.
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Deregulation of MUC4 in gastric adenocarcinoma: potential pathobiological implication in poorly differentiated non-signet ring cell type gastric cancer. Br J Cancer. 2008 Sep 16; 99(6):949-56.