Activating Transcription Factor 6
"Activating Transcription Factor 6" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS that is synthesized as a membrane-bound protein in the ENDOPLASMIC RETICULUM. In response to endoplasmic reticulum stress it translocates to the GOLGI APPARATUS. It is activated by PROTEASES and then moves to the CELL NUCLEUS to regulate GENETIC TRANSCRIPTION of GENES involved in the unfolded protein response.
Descriptor ID |
D051702
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MeSH Number(s) |
D12.644.360.011 D12.776.260.108.061.968 D12.776.476.011 D12.776.930.127.061.968
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Activating Transcription Factor 6".
Below are MeSH descriptors whose meaning is more specific than "Activating Transcription Factor 6".
This graph shows the total number of publications written about "Activating Transcription Factor 6" by people in this website by year, and whether "Activating Transcription Factor 6" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2007 | 1 | 0 | 1 |
2011 | 0 | 2 | 2 |
2016 | 0 | 1 | 1 |
2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Activating Transcription Factor 6" by people in Profiles.
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Endoplasmic Reticulum Protein TXNDC5 Augments Myocardial Fibrosis by Facilitating Extracellular Matrix Protein Folding and Redox-Sensitive Cardiac Fibroblast Activation. Circ Res. 2018 04 13; 122(8):1052-1068.
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Intravenous Lipid Infusion Induces Endoplasmic Reticulum Stress in Endothelial Cells and Blood Mononuclear Cells of Healthy Adults. J Am Heart Assoc. 2016 Jan 11; 5(1).
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Unfolded protein response signaling and MAP kinase pathways underlie pathogenesis of arsenic-induced cutaneous inflammation. Cancer Prev Res (Phila). 2011 Dec; 4(12):2101-9.
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Dysregulation of the unfolded protein response in db/db mice with diet-induced steatohepatitis. Hepatology. 2011 Nov; 54(5):1600-9.
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Nucleobindin 1 controls the unfolded protein response by inhibiting ATF6 activation. J Biol Chem. 2007 Oct 05; 282(40):29264-72.