 Monomeric GTP-Binding Proteins
"Monomeric GTP-Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of monomeric, low molecular weight (20-25 kDa) GTP-binding proteins that regulate a variety of intracellular processes. The GTP bound form of the protein is active and limited by its inherent GTPase activity, which is controlled by an array of GTPase activators, GDP dissociation inhibitors, and guanine nucleotide exchange factors. This enzyme was formerly listed as EC 3.6.1.47
| Descriptor ID |
D020559
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| MeSH Number(s) |
D08.811.277.040.330.300.400 D12.644.360.525 D12.776.157.325.515 D12.776.476.525
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| Concept/Terms |
Monomeric GTP-Binding Proteins- Monomeric GTP-Binding Proteins
- Monomeric GTP Binding Proteins
- Small GTPases
- GTPases, Small
- Monomeric G-Proteins
- Monomeric G Proteins
- Small G-Proteins
- G-Proteins, Small
- Small G Proteins
- G-Proteins, Monomeric
- G Proteins, Monomeric
- GTP-Binding Proteins, Monomeric
- GTP Binding Proteins, Monomeric
ras-Related GTPases- ras-Related GTPases
- GTPases, ras-Related
- ras Related GTPases
- ras-Related GTP-Binding Proteins
- GTP-Binding Proteins, ras-Related
- Proteins, ras-Related GTP-Binding
- ras Related GTP Binding Proteins
- ras-Related G-Proteins
- G-Proteins, ras-Related
- ras Related G Proteins
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Below are MeSH descriptors whose meaning is more general than "Monomeric GTP-Binding Proteins".
Below are MeSH descriptors whose meaning is more specific than "Monomeric GTP-Binding Proteins".
This graph shows the total number of publications written about "Monomeric GTP-Binding Proteins" by people in this website by year, and whether "Monomeric GTP-Binding Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 | | 1998 | 1 | 0 | 1 | | 1999 | 1 | 0 | 1 | | 2000 | 1 | 2 | 3 | | 2001 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2013 | 1 | 0 | 1 | | 2014 | 0 | 1 | 1 | | 2016 | 2 | 0 | 2 | | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Monomeric GTP-Binding Proteins" by people in Profiles.
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Rich A, Glotzer M. Small GTPases modulate intrinsic and extrinsic forces that control epithelial folding in Drosophila embryos. Small GTPases. 2021 Sep-Nov; 12(5-6):416-428.
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Prakash P, Gorfe AA. Membrane orientation dynamics of lipid-modified small GTPases. Small GTPases. 2017 07 03; 8(3):129-138.
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Isabella AJ, Horne-Badovinac S. Rab10-Mediated Secretion Synergizes with Tissue Movement to Build a Polarized Basement Membrane Architecture for Organ Morphogenesis. Dev Cell. 2016 07 11; 38(1):47-60.
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Nagalingam RS, Sundaresan NR, Noor M, Gupta MP, Solaro RJ, Gupta M. Deficiency of cardiomyocyte-specific microRNA-378 contributes to the development of cardiac fibrosis involving a transforming growth factor ß (TGFß1)-dependent paracrine mechanism. J Biol Chem. 2014 Sep 26; 289(39):27199-27215.
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Shahani N, Pryor W, Swarnkar S, Kholodilov N, Thinakaran G, Burke RE, Subramaniam S. Rheb GTPase regulates ß-secretase levels and amyloid ß generation. J Biol Chem. 2014 Feb 28; 289(9):5799-808.
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Hofmann H, Norton TD, Schultz ML, Polsky SB, Sunseri N, Landau NR. Inhibition of CUL4A Neddylation causes a reversible block to SAMHD1-mediated restriction of HIV-1. J Virol. 2013 Nov; 87(21):11741-50.
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Lerner DW, McCoy D, Isabella AJ, Mahowald AP, Gerlach GF, Chaudhry TA, Horne-Badovinac S. A Rab10-dependent mechanism for polarized basement membrane secretion during organ morphogenesis. Dev Cell. 2013 Jan 28; 24(2):159-68.
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Seo JH, Suenaga A, Hatakeyama M, Taiji M, Imamoto A. Structural and functional basis of a role for CRKL in a fibroblast growth factor 8-induced feed-forward loop. Mol Cell Biol. 2009 Jun; 29(11):3076-87.
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Birukova AA, Zagranichnaya T, Alekseeva E, Bokoch GM, Birukov KG. Epac/Rap and PKA are novel mechanisms of ANP-induced Rac-mediated pulmonary endothelial barrier protection. J Cell Physiol. 2008 Jun; 215(3):715-24.
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Birukova AA, Malyukova I, Mikaelyan A, Fu P, Birukov KG. Tiam1 and betaPIX mediate Rac-dependent endothelial barrier protective response to oxidized phospholipids. J Cell Physiol. 2007 Jun; 211(3):608-17.
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