T Cell Transcription Factor 1
"T Cell Transcription Factor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A TCF transcription factor that was originally identified as a DNA-binding protein that interacts with the enhancers of T-CELL RECEPTOR ALPHA GENES. It plays a role in T-LYMPHOCYTE development.
|T Cell Transcription Factor 1
- T Cell Transcription Factor 1
- TCF-1 Transcription Factor
- TCF 1 Transcription Factor
- Transcription Factor, TCF-1
- Transcription Factor 7
- T Cell Factor 1
Below are MeSH descriptors whose meaning is more general than "T Cell Transcription Factor 1".
Below are MeSH descriptors whose meaning is more specific than "T Cell Transcription Factor 1".
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Below are the most recent publications written about "T Cell Transcription Factor 1" by people in Profiles.
Tcf-1 protects anti-tumor TCR-engineered CD8+ T-cells from GzmB mediated self-destruction. Cancer Immunol Immunother. 2022 Dec; 71(12):2881-2898.
Wnt-?-catenin activation epigenetically reprograms Treg cells in inflammatory bowel disease and dysplastic progression. Nat Immunol. 2021 04; 22(4):471-484.
TCF1 links GIPR signaling to the control of beta cell function and survival. Nat Med. 2016 Jan; 22(1):84-90.
?-Catenin promotes colitis and colon cancer through imprinting of proinflammatory properties in T cells. Sci Transl Med. 2014 Feb 26; 6(225):225ra28.
?-Catenin induces T-cell transformation by promoting genomic instability. Proc Natl Acad Sci U S A. 2014 Jan 07; 111(1):391-6.
T-cell factor 1 is a gatekeeper for T-cell specification in response to Notch signaling. Proc Natl Acad Sci U S A. 2011 Dec 13; 108(50):20060-5.
Insights into the organization of dorsal spinal cord pathways from an evolutionarily conserved raldh2 intronic enhancer. Development. 2010 Feb; 137(3):507-18.
Beta-catenin/Tcf determines the outcome of thymic selection in response to alphabetaTCR signaling. J Immunol. 2009 Sep 15; 183(6):3873-84.