"NADPH Oxidase 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An NADPH oxidase that is expressed by PHAGOCYTES where it transfers electrons across the plasma membrane from cytosolic NADPH to molecular oxygen on the exterior. It regulates proton (H+) flux into resting phagocytes to control intracellular pH. Mutations in the CYBB gene are associated with X-LINKED CHRONIC GRANULOMATOUS DISEASE.
| Descriptor ID |
D000074662
|
| MeSH Number(s) |
D08.811.682.608.575.875 D12.776.331.894.875 D12.776.543.653.875
|
| Concept/Terms |
NADPH Oxidase 2- NADPH Oxidase 2
- Oxidase 2, NADPH
- Chronic Granulomatous Disease Protein
- GP91-PHOX Protein
- GP91 PHOX Protein
- CYBB Protein
- Cytochrome B-245 Beta Chain
- Cytochrome B 245 Beta Chain
- NOX2 Protein
|
Below are MeSH descriptors whose meaning is more general than "NADPH Oxidase 2".
Below are MeSH descriptors whose meaning is more specific than "NADPH Oxidase 2".
This graph shows the total number of publications written about "NADPH Oxidase 2" by people in this website by year, and whether "NADPH Oxidase 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2011 | 0 | 2 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 2 | 2 |
| 2014 | 0 | 2 | 2 |
| 2015 | 0 | 2 | 2 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 2 | 2 |
| 2018 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "NADPH Oxidase 2" by people in Profiles.
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X-linked Chronic Granulomatous Disease Presenting with Mediastinal Lipoblastoma and Adjacent Pneumonia. J Clin Immunol. 2021 11; 41(8):1969-1971.
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Attenuation of Oxidative Injury With Targeted Expression of NADPH Oxidase 2 Short Hairpin RNA Prevents Onset and Maintenance of Electrical Remodeling in the Canine Atrium: A Novel Gene Therapy Approach to Atrial Fibrillation. Circulation. 2020 09 29; 142(13):1261-1278.
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Transcriptional profiling identifies novel regulators of macrophage polarization. PLoS One. 2018; 13(12):e0208602.
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Dendritic Cells but Not Macrophages Sense Tumor Mitochondrial DNA for Cross-priming through Signal Regulatory Protein a Signaling. Immunity. 2017 08 15; 47(2):363-373.e5.
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Intermittent hypoxia causes NOX2-dependent remodeling of atrial connexins. BMC Cell Biol. 2017 01 17; 18(Suppl 1):7.
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Perivascular Mast Cells Govern Shear Stress-Induced Arteriogenesis by Orchestrating Leukocyte Function. Cell Rep. 2016 08 23; 16(8):2197-2207.
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Regulation of cellular oxidative stress and apoptosis by G protein-coupled receptor kinase-2; The role of NADPH oxidase 4. Cell Signal. 2016 Mar; 28(3):190-203.
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HIF-1a activation by intermittent hypoxia requires NADPH oxidase stimulation by xanthine oxidase. PLoS One. 2015; 10(3):e0119762.
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Sleep fragmentation in mice induces nicotinamide adenine dinucleotide phosphate oxidase 2-dependent mobilization, proliferation, and differentiation of adipocyte progenitors in visceral white adipose tissue. Sleep. 2014 May 01; 37(5):999-1009.
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Nicotinamide adenine dinucleotide phosphate oxidase is differentially regulated in normal myometrium versus leiomyoma. Reprod Sci. 2014 Sep; 21(9):1145-52.