"NADPH Oxidase 4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An NADPH oxidase that is strongly expressed in the kidney. It forms a complex with CYBA-P22PHOX and produces intracellular SUPEROXIDES that may regulate cellular signaling in APOPTOSIS; BONE RESORPTION; and NF-KAPPA B activation.
| Descriptor ID |
D000074663
|
| MeSH Number(s) |
D08.811.682.608.575.937 D12.776.331.894.937 D12.776.543.653.937
|
| Concept/Terms |
NADPH Oxidase 4- NADPH Oxidase 4
- Oxidase 4, NADPH
- Renal NAD(P)H Oxidase
- Nox4 Protein
- Renox NAD(P)H Oxidase
|
Below are MeSH descriptors whose meaning is more general than "NADPH Oxidase 4".
Below are MeSH descriptors whose meaning is more specific than "NADPH Oxidase 4".
This graph shows the total number of publications written about "NADPH Oxidase 4" by people in this website by year, and whether "NADPH Oxidase 4" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 2 | 2 |
| 2018 | 1 | 1 | 2 |
| 2020 | 1 | 1 | 2 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "NADPH Oxidase 4" by people in Profiles.
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miR-100a-5p-enriched exosomes derived from mesenchymal stem cells enhance the anti-oxidant effect in a Parkinson's disease model via regulation of Nox4/ROS/Nrf2 signaling. J Transl Med. 2023 10 24; 21(1):747.
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TLR4 activation induces inflammatory vascular permeability via Dock1 targeting and NOX4 upregulation. Biochim Biophys Acta Mol Basis Dis. 2022 12 01; 1868(12):166562.
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Lysine demethylase KDM6B regulates HIF-1a-mediated systemic and cellular responses to intermittent hypoxia. Physiol Genomics. 2021 09 01; 53(9):385-394.
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Hypoxia-inducible factor-1 mediates pancreatic ß-cell dysfunction by intermittent hypoxia. Am J Physiol Cell Physiol. 2020 11 01; 319(5):C922-C932.
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Immunotherapeutic Response in Tumors Is Affected by Microenvironmental ROS. Cancer Res. 2020 05 01; 80(9):1799-1800.
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ROS modifiers and NOX4 affect the expression of the survivin-associated radio-adaptive response. Free Radic Biol Med. 2018 08 01; 123:39-52.
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Endoplasmic Reticulum Protein TXNDC5 Augments Myocardial Fibrosis by Facilitating Extracellular Matrix Protein Folding and Redox-Sensitive Cardiac Fibroblast Activation. Circ Res. 2018 04 13; 122(8):1052-1068.
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Regulation of cellular oxidative stress and apoptosis by G protein-coupled receptor kinase-2; The role of NADPH oxidase 4. Cell Signal. 2016 Mar; 28(3):190-203.
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Regulation of mitochondrial oxidative stress by ß-arrestins in cultured human cardiac fibroblasts. Dis Model Mech. 2015 Dec; 8(12):1579-89.
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Nicotinamide adenine dinucleotide phosphate oxidase is differentially regulated in normal myometrium versus leiomyoma. Reprod Sci. 2014 Sep; 21(9):1145-52.