"CRISPR-Cas Systems" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Adaptive antiviral defense mechanisms, in archaea and bacteria, based on DNA repeat arrays called CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS (CRISPR elements) that function in conjunction with CRISPR-ASSOCIATED PROTEINS (Cas proteins). Several types have been distinguished, including Type I, Type II, and Type III, based on signature motifs of CRISPR-ASSOCIATED PROTEINS.
| Descriptor ID |
D064113
|
| MeSH Number(s) |
G05.308.203.374.394
|
| Concept/Terms |
CRISPR-Cas Systems- CRISPR-Cas Systems
- CRISPR Cas Systems
- CRISPR-Cas System
- System, CRISPR-Cas
- Systems, CRISPR-Cas
|
Below are MeSH descriptors whose meaning is more general than "CRISPR-Cas Systems".
Below are MeSH descriptors whose meaning is more specific than "CRISPR-Cas Systems".
This graph shows the total number of publications written about "CRISPR-Cas Systems" by people in this website by year, and whether "CRISPR-Cas Systems" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 1 | 1 | 2 |
| 2015 | 2 | 3 | 5 |
| 2016 | 2 | 5 | 7 |
| 2017 | 5 | 7 | 12 |
| 2018 | 5 | 4 | 9 |
| 2019 | 0 | 5 | 5 |
| 2020 | 3 | 8 | 11 |
| 2021 | 2 | 6 | 8 |
| 2022 | 2 | 6 | 8 |
| 2023 | 4 | 4 | 8 |
| 2024 | 1 | 8 | 9 |
| 2025 | 2 | 7 | 9 |
| 2026 | 0 | 2 | 2 |
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Below are the most recent publications written about "CRISPR-Cas Systems" by people in Profiles.
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AI-guided CRISPR screening reveals therapeutic targets in psoriasis. Nat Commun. 2026 Jul 06; 17(1).
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Engineering a human-based translational activator for targeted protein expression restoration. Nucleic Acids Res. 2026 Feb 05; 54(4).
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Genome-wide CRISPR Screen Identifies Sec31A as a Key Regulator of Alpha Cell Survival. Nat Commun. 2025 Oct 15; 16(1):9159.
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In vivo CRISPR screens identify modifiers of CAR T cell function in myeloma. Nature. 2025 10; 646(8086):953-962.
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Mutations of schizophrenia risk gene SETD1A dysregulate synaptic function in human neurons. Mol Psychiatry. 2025 Dec; 30(12):5680-5693.
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A Genetically-Engineered Thyroid Gland Built for Selective Triiodothyronine Secretion. Int J Mol Sci. 2025 Jul 24; 26(15).
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High-precision cytosine base editors by evolving nucleic-acid-recognition hotspots in deaminase. Nat Biotechnol. 2026 Apr; 44(4):587-601.
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Charting the development and engineering of CRISPR base editors: lessons and inspirations. Cell Chem Biol. 2025 06 19; 32(6):789-808.
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Mitochondrial fatty acid synthesis and MECR regulate CD4+ T cell function and oxidative metabolism. J Immunol. 2025 May 01; 214(5):958-976.
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Herpesviruses mimic zygotic genome activation to promote viral replication. Nat Commun. 2025 Jan 16; 16(1):710.