"CRISPR-Cas Systems" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Adaptive antiviral defense mechanisms, in archaea and bacteria, based on DNA repeat arrays called CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS (CRISPR elements) that function in conjunction with CRISPR-ASSOCIATED PROTEINS (Cas proteins). Several types have been distinguished, including Type I, Type II, and Type III, based on signature motifs of CRISPR-ASSOCIATED PROTEINS.
| Descriptor ID |
D064113
|
| MeSH Number(s) |
G05.308.203.374.394
|
| Concept/Terms |
CRISPR-Cas Systems- CRISPR-Cas Systems
- CRISPR Cas Systems
- CRISPR-Cas System
- System, CRISPR-Cas
- Systems, CRISPR-Cas
|
Below are MeSH descriptors whose meaning is more general than "CRISPR-Cas Systems".
Below are MeSH descriptors whose meaning is more specific than "CRISPR-Cas Systems".
This graph shows the total number of publications written about "CRISPR-Cas Systems" by people in this website by year, and whether "CRISPR-Cas Systems" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 1 | 1 | 2 |
| 2015 | 2 | 3 | 5 |
| 2016 | 2 | 5 | 7 |
| 2017 | 4 | 6 | 10 |
| 2018 | 4 | 4 | 8 |
| 2019 | 0 | 4 | 4 |
| 2020 | 1 | 5 | 6 |
| 2021 | 2 | 5 | 7 |
| 2022 | 2 | 2 | 4 |
| 2023 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "CRISPR-Cas Systems" by people in Profiles.
-
Neoantigen-targeted CD8+ T cell responses with PD-1 blockade therapy. Nature. 2023 Mar; 615(7953):697-704.
-
Non-viral precision T?cell receptor replacement for personalized cell therapy. Nature. 2023 Mar; 615(7953):687-696.
-
The potential of CRISPR-Cas9 prime editing for cardiovascular disease research and therapy. Curr Opin Cardiol. 2022 09 01; 37(5):413-418.
-
CASowary: CRISPR-Cas13 guide RNA predictor for transcript depletion. BMC Genomics. 2022 Mar 02; 23(1):172.
-
The SWI/SNF chromatin remodeling assemblies BAF and PBAF differentially regulate cell cycle exit and cellular invasion in vivo. PLoS Genet. 2022 01; 18(1):e1009981.
-
BAd-CRISPR: Inducible gene knockout in interscapular brown adipose tissue of adult mice. J Biol Chem. 2021 12; 297(6):101402.
-
TET2 and DNMT3A Mutations Exert Divergent Effects on DNA Repair and Sensitivity of Leukemia Cells to PARP Inhibitors. Cancer Res. 2021 10 01; 81(19):5089-5101.
-
Programmable technologies to manipulate gene expression at the RNA level. Curr Opin Chem Biol. 2021 10; 64:27-37.
-
A review on current diagnostic techniques for COVID-19. Expert Rev Mol Diagn. 2021 02; 21(2):141-160.
-
Targeting RLIP with CRISPR/Cas9 controls tumor growth. Carcinogenesis. 2021 02 11; 42(1):48-57.