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Weixin Tang

TitleAssistant Professor
InstitutionUniversity of Chicago
DepartmentChemistry
AddressChicago IL 60637
Email
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Wu Y, Xiao YL, Tang W. High-precision cytosine base editors by evolving nucleic-acid-recognition hotspots in deaminase. Nat Biotechnol. 2026 Apr; 44(4):587-601. PMID: 40624252; PMCID: PMC12240478.
      Citations: 4     Fields:    Translation:HumansCells
    2. Zou S, Sun Y, Tang W. Charting the development and engineering of CRISPR base editors: lessons and inspirations. Cell Chem Biol. 2025 06 19; 32(6):789-808. PMID: 40480225; PMCID: PMC12239427.
      Citations: 4     Fields:    Translation:HumansCells
    3. Yan H, Tan X, Zou S, Sun Y, Ke A, Tang W. Assessing and engineering the IscB-?RNA system for programmed genome editing. Nat Chem Biol. 2024 Dec; 20(12):1617-1628. PMID: 38977787; PMCID: PMC12213078.
      Citations: 20     Fields:    Translation:HumansCells
    4. Yan H, Tang W. Programmed RNA editing with an evolved bacterial adenosine deaminase. Nat Chem Biol. 2024 Oct; 20(10):1361-1370. PMID: 38969862; PMCID: PMC12090699.
      Citations: 6     Fields:    Translation:HumansCells
    5. Xiao YL, Wu Y, Tang W. An adenine base editor variant expands context compatibility. Nat Biotechnol. 2024 Sep; 42(9):1442-1453. PMID: 38168987.
      Citations: 22     Fields:    Translation:HumansCells
    6. Wu T, Liu C, Zou S, Lyu R, Yang B, Yan H, Zhao M, Tang W. Author Correction: An engineered hypercompact CRISPR-Cas12f system with boosted gene-editing activity. Nat Chem Biol. 2024 Jan; 20(1):129. PMID: 38040979.
      Citations:    Fields:    
    7. Wu T, Liu C, Zou S, Lyu R, Yang B, Yan H, Zhao M, Tang W. An engineered hypercompact CRISPR-Cas12f system with boosted gene-editing activity. Nat Chem Biol. 2023 11; 19(11):1384-1393. PMID: 37400536; PMCID: PMC10625714.
      Citations: 49     Fields:    Translation:HumansAnimals
    8. Xiao YL, Liu S, Ge R, Wu Y, He C, Chen M, Tang W. Transcriptome-wide profiling and quantification of N6-methyladenosine by enzyme-assisted adenosine deamination. Nat Biotechnol. 2023 07; 41(7):993-1003. PMID: 36593412; PMCID: PMC10625715.
      Citations: 99     Fields:    Translation:AnimalsCells
    9. Tang W, Bobeica SC, Wang L, van der Donk WA. CylA is a sequence-specific protease involved in toxin biosynthesis. J Ind Microbiol Biotechnol. 2019 Mar; 46(3-4):537-549. PMID: 30484123; PMCID: PMC6450559.
      Citations: 15     Fields:    Translation:Cells
    10. Hu JH, Miller SM, Geurts MH, Tang W, Chen L, Sun N, Zeina CM, Gao X, Rees HA, Lin Z, Liu DR. Evolved Cas9 variants with broad PAM compatibility and high DNA specificity. Nature. 2018 04 05; 556(7699):57-63. PMID: 29512652; PMCID: PMC5951633.
      Citations: 824     Fields:    Translation:HumansCells
    11. Tang W, Liu DR. Rewritable multi-event analog recording in bacterial and mammalian cells. Science. 2018 Apr 13; 360(6385). PMID: 29449507; PMCID: PMC5898985.
      Citations: 113     Fields:    Translation:HumansCells
    12. Tang W, Hu JH, Liu DR. Aptazyme-embedded guide RNAs enable ligand-responsive genome editing and transcriptional activation. Nat Commun. 2017 Jun 28; 8:15939. PMID: 28656978; PMCID: PMC5493748.
      Citations: 88     Fields:    Translation:HumansCells
    13. Tang W, Thibodeaux GN, van der Donk WA. The Enterococcal Cytolysin Synthetase Coevolves with Substrate for Stereoselective Lanthionine Synthesis. ACS Chem Biol. 2016 09 16; 11(9):2438-46. PMID: 27348535; PMCID: PMC5289929.
      Citations: 16     Fields:    Translation:Cells
    14. Tang W, Dong SH, Repka LM, He C, Nair SK, van der Donk WA. Applications of the class II lanthipeptide protease LicP for sequence-specific, traceless peptide bond cleavage. Chem Sci. 2015 Nov 01; 6(11):6270-6279. PMID: 30090246; PMCID: PMC6054071.
      Citations: 13     
    15. Dong SH, Tang W, Lukk T, Yu Y, Nair SK, van der Donk WA. The enterococcal cytolysin synthetase has an unanticipated lipid kinase fold. Elife. 2015 Jul 30; 4. PMID: 26226635; PMCID: PMC4550811.
      Citations: 51     Fields:    Translation:HumansCells
    16. Tang W, Houk KN, van der Donk WA, Jiménez-Osés G. Substrate control in stereoselective lanthionine biosynthesis. Nat Chem. 2015 Jan; 7(1):57-64. PMID: 25515891; PMCID: PMC4270103.
      Citations: 57     Fields:    Translation:Cells
    17. Tang W, van der Donk WA. The sequence of the enterococcal cytolysin imparts unusual lanthionine stereochemistry. Nat Chem Biol. 2013 Mar; 9(3):157-9. PMID: 23314913; PMCID: PMC3578037.
      Citations: 63     Fields:    Translation:Cells
    18. Tang W, van der Donk WA. Structural characterization of four prochlorosins: a novel class of lantipeptides produced by planktonic marine cyanobacteria. Biochemistry. 2012 May 29; 51(21):4271-9. PMID: 22574919; PMCID: PMC3361976.
      Citations: 62     Fields:    Translation:Cells
    19. Garg N, Tang W, Goto Y, Nair SK, van der Donk WA. Lantibiotics from Geobacillus thermodenitrificans. Proc Natl Acad Sci U S A. 2012 Apr 03; 109(14):5241-6. PMID: 22431611; PMCID: PMC3325677.
      Citations: 81     Fields:    Translation:Cells
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