"Clonal Anergy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Functional inactivation of T- or B-lymphocytes rendering them incapable of eliciting an immune response to antigen. This occurs through different mechanisms in the two kinds of lymphocytes and can contribute to SELF TOLERANCE.
| Descriptor ID |
D017635
|
| MeSH Number(s) |
G12.535.425.100
|
| Concept/Terms |
Clonal Anergy- Clonal Anergy
- Anergies, Clonal
- Anergy, Clonal
- Clonal Anergies
|
Below are MeSH descriptors whose meaning is more general than "Clonal Anergy".
Below are MeSH descriptors whose meaning is more specific than "Clonal Anergy".
This graph shows the total number of publications written about "Clonal Anergy" by people in this website by year, and whether "Clonal Anergy" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1996 | 3 | 0 | 3 |
| 1997 | 1 | 0 | 1 |
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2006 | 2 | 0 | 2 |
| 2008 | 1 | 1 | 2 |
| 2009 | 1 | 1 | 2 |
| 2012 | 2 | 0 | 2 |
| 2013 | 2 | 0 | 2 |
| 2017 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Clonal Anergy" by people in Profiles.
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Cbl-b deficiency prevents functional but not phenotypic T cell anergy. J Exp Med. 2021 07 05; 218(7).
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Transplantation tolerance: don't forget about the B cells. Clin Exp Immunol. 2017 08; 189(2):171-180.
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Loss of anergic B cells in prediabetic and new-onset type 1 diabetic patients. Diabetes. 2015 May; 64(5):1703-12.
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Conditional deletion of PTEN in peripheral T cells augments TCR-mediated activation but does not abrogate CD28 dependency or prevent anergy induction. J Immunol. 2013 Aug 15; 191(4):1677-85.
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Egr2-dependent gene expression profiling and ChIP-Seq reveal novel biologic targets in T cell anergy. Mol Immunol. 2013 Oct; 55(3-4):283-91.
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Engineering antigens for in situ erythrocyte binding induces T-cell deletion. Proc Natl Acad Sci U S A. 2013 Jan 02; 110(1):E60-8.
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Transcriptional regulator early growth response gene 2 (Egr2) is required for T cell anergy in vitro and in vivo. J Exp Med. 2012 Nov 19; 209(12):2157-63.
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FOXP3 inhibits activation-induced NFAT2 expression in T cells thereby limiting effector cytokine expression. J Immunol. 2009 Jul 15; 183(2):907-15.
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Endocytic sequestration of the B cell antigen receptor and toll-like receptor 9 in anergic cells. Proc Natl Acad Sci U S A. 2009 Apr 14; 106(15):6262-7.
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Functional anergy in a subpopulation of naive B cells from healthy humans that express autoreactive immunoglobulin receptors. J Exp Med. 2009 Jan 16; 206(1):139-51.