"Poly(A)-Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins that bind to the 3' polyadenylated region of MRNA. When complexed with RNA the proteins serve an array of functions such as stabilizing the 3' end of RNA, promoting poly(A) synthesis and stimulating mRNA translation.
- Poly(A)-Binding Proteins
- Poly(A)-Binding Protein
- Poly A-Binding Proteins
- Poly A Binding Proteins
- Poly(A)+ mRNA Binding Protein
- Poly A-Binding Protein
- Poly A Binding Protein
Below are MeSH descriptors whose meaning is more general than "Poly(A)-Binding Proteins".
Below are MeSH descriptors whose meaning is more specific than "Poly(A)-Binding Proteins".
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Below are the most recent publications written about "Poly(A)-Binding Proteins" by people in Profiles.
Chaperones directly and efficiently disperse stress-triggered biomolecular condensates. Mol Cell. 2022 02 17; 82(4):741-755.e11.
TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics. Neuron. 2017 Aug 16; 95(4):808-816.e9.
Stress-Triggered Phase Separation Is an Adaptive, Evolutionarily Tuned Response. Cell. 2017 03 09; 168(6):1028-1040.e19.
Post-transcriptional processing of cellular RNAs in herpes simplex virus-infected cells. Biochem Soc Trans. 2004 Nov; 32(Pt 5):697-701.
Herpes simplex virus 1 induces cytoplasmic accumulation of TIA-1/TIAR and both synthesis and cytoplasmic accumulation of tristetraprolin, two cellular proteins that bind and destabilize AU-rich RNAs. J Virol. 2004 Aug; 78(16):8582-92.
Cytotoxicity and apoptosis in human renal allografts: identification, distribution, and quantitation of cells with a cytotoxic granule protein GMP-17 (TIA-1) and cells with fragmented nuclear DNA. Lab Invest. 1997 May; 76(5):639-49.