Cyclin-Dependent Kinase 9
"Cyclin-Dependent Kinase 9" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multifunctional CDC2 kinase-related kinase that plays roles in transcriptional elongation, CELL DIFFERENTIATION, and APOPTOSIS. It is found associated with CYCLIN T and is a component of POSITIVE TRANSCRIPTIONAL ELONGATION FACTOR B.
| Descriptor ID |
D042863
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| MeSH Number(s) |
D08.811.641.752 D08.811.913.696.620.682.700.646.500.500.750 D12.644.360.250.067.900 D12.776.167.200.067.900 D12.776.476.250.067.900 D12.776.930.955.500.500
|
| Concept/Terms |
Cyclin-Dependent Kinase 9- Cyclin-Dependent Kinase 9
- Cyclin Dependent Kinase 9
- PITALRE Kinase
- Cdk9 Protein Kinase
- CDK9 Kinase
- Cdc2-related Kinase PITALRE
- Cdc2 related Kinase PITALRE
- Kinase PITALRE, Cdc2-related
- PITALRE, Cdc2-related Kinase
|
Below are MeSH descriptors whose meaning is more general than "Cyclin-Dependent Kinase 9".
Below are MeSH descriptors whose meaning is more specific than "Cyclin-Dependent Kinase 9".
This graph shows the total number of publications written about "Cyclin-Dependent Kinase 9" by people in this website by year, and whether "Cyclin-Dependent Kinase 9" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2018 | 1 | 1 | 2 |
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Below are the most recent publications written about "Cyclin-Dependent Kinase 9" by people in Profiles.
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Targeting CDK9 Reactivates Epigenetically Silenced Genes in Cancer. Cell. 2018 11 15; 175(5):1244-1258.e26.
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RNA cytosine methylation and methyltransferases mediate chromatin organization and 5-azacytidine response and resistance in leukaemia. Nat Commun. 2018 03 21; 9(1):1163.
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Role of cdk9 in the optimization of expression of the genes regulated by ICP22 of herpes simplex virus 1. J Virol. 2008 Nov; 82(21):10591-9.
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The carboxyl-terminal domain of RNA polymerase II is phosphorylated by a complex containing cdk9 and infected-cell protein 22 of herpes simplex virus 1. J Virol. 2005 Jun; 79(11):6757-62.