bcl-2 Homologous Antagonist-Killer Protein
"bcl-2 Homologous Antagonist-Killer Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multi-domain mitochondrial membrane protein and member of the bcl-2 Protein family. Bak protein interacts with TUMOR SUPPRESSOR PROTEIN P53 and promotes APOPTOSIS.
|bcl-2 Homologous Antagonist-Killer Protein
- bcl-2 Homologous Antagonist-Killer Protein
- bcl 2 Homologous Antagonist Killer Protein
- bcl2 Homologous Antagonist-Killer Protein
- bcl2 Homologous Antagonist Killer Protein
- Bak Protein
Below are MeSH descriptors whose meaning is more general than "bcl-2 Homologous Antagonist-Killer Protein".
Below are MeSH descriptors whose meaning is more specific than "bcl-2 Homologous Antagonist-Killer Protein".
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Below are the most recent publications written about "bcl-2 Homologous Antagonist-Killer Protein" by people in Profiles.
A Zombie LIF Gene in Elephants Is Upregulated by TP53 to Induce Apoptosis in Response to DNA Damage. Cell Rep. 2018 08 14; 24(7):1765-1776.
Pancreatic ?-Cell Death due to Pdx-1 Deficiency Requires Multi-BH Domain Protein Bax but Not Bak. J Biol Chem. 2016 Jun 24; 291(26):13529-34.
An interconnected hierarchical model of cell death regulation by the BCL-2 family. Nat Cell Biol. 2015 Oct; 17(10):1270-81.
Nuclear localization of the mitochondrial factor HIGD1A during metabolic stress. PLoS One. 2013; 8(4):e62758.
NF-?B controls energy homeostasis and metabolic adaptation by upregulating mitochondrial respiration. Nat Cell Biol. 2011 Aug 28; 13(10):1272-9.
Mitochondrial oxidant stress triggers cell death in simulated ischemia-reperfusion. Biochim Biophys Acta. 2011 Jul; 1813(7):1382-94.
BID, BIM, and PUMA are essential for activation of the BAX- and BAK-dependent cell death program. Science. 2010 Dec 03; 330(6009):1390-3.
Epithelial cell death is an important contributor to oxidant-mediated acute lung injury. Am J Respir Crit Care Med. 2011 Apr 15; 183(8):1043-54.
Blocking the mitochondrial apoptotic pathway preserves motor neuron viability and function in a mouse model of amyotrophic lateral sclerosis. J Clin Invest. 2010 Oct; 120(10):3673-9.
Stepwise activation of BAX and BAK by tBID, BIM, and PUMA initiates mitochondrial apoptosis. Mol Cell. 2009 Nov 13; 36(3):487-99.