bcl-2-Associated X Protein
"bcl-2-Associated X Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the Bcl-2 protein family and homologous partner of C-BCL-2 PROTO-ONCOGENE PROTEIN. It regulates the release of CYTOCHROME C and APOPTOSIS INDUCING FACTOR from the MITOCHONDRIA. Several isoforms of BCL2-associated X protein occur due to ALTERNATIVE SPLICING of the mRNA for this protein.
| Descriptor ID |
D051028
|
| MeSH Number(s) |
D12.644.360.075.718.400 D12.776.476.075.718.400
|
| Concept/Terms |
bcl-2-Associated X Protein- bcl-2-Associated X Protein
- Protein, bcl-2-Associated X
- X Protein, bcl-2-Associated
- bcl 2 Associated X Protein
- Bax Apoptosis Regulator Protein
- Bax Protein
- bcl2-Associated X Protein
- bcl2 Associated X Protein
|
Below are MeSH descriptors whose meaning is more general than "bcl-2-Associated X Protein".
Below are MeSH descriptors whose meaning is more specific than "bcl-2-Associated X Protein".
This graph shows the total number of publications written about "bcl-2-Associated X Protein" by people in this website by year, and whether "bcl-2-Associated X Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2000 | 0 | 4 | 4 |
| 2002 | 0 | 4 | 4 |
| 2003 | 0 | 3 | 3 |
| 2004 | 0 | 2 | 2 |
| 2006 | 0 | 2 | 2 |
| 2007 | 1 | 3 | 4 |
| 2008 | 0 | 6 | 6 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 1 | 2 |
| 2011 | 0 | 2 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 4 | 4 |
| 2016 | 1 | 1 | 2 |
| 2017 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "bcl-2-Associated X Protein" by people in Profiles.
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EZH2 activates Wnt/ß-catenin signaling in human uterine fibroids, which is inhibited by the natural compound methyl jasmonate. F S Sci. 2023 08; 4(3):239-256.
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Muscone suppresses myocardial ischemia damage by regulating PI3K/Akt signaling pathway. Biochim Biophys Acta Mol Basis Dis. 2022 12 01; 1868(12):166539.
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Regulatory variants in TCF7L2 are associated with thoracic aortic aneurysm. Am J Hum Genet. 2021 09 02; 108(9):1578-1589.
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A Zombie LIF Gene in Elephants Is Upregulated by TP53 to Induce Apoptosis in Response to DNA Damage. Cell Rep. 2018 08 14; 24(7):1765-1776.
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Conserved salt-bridge competition triggered by phosphorylation regulates the protein interactome. Proc Natl Acad Sci U S A. 2017 12 19; 114(51):13453-13458.
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The functional domains for Bax?2 aggregate-mediated caspase 8-dependent cell death. Exp Cell Res. 2017 10 15; 359(2):342-355.
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Pancreatic ß-Cell Death due to Pdx-1 Deficiency Requires Multi-BH Domain Protein Bax but Not Bak. J Biol Chem. 2016 Jun 24; 291(26):13529-34.
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A High-Throughput Cell-Based Screen Identified a 2-[(E)-2-Phenylvinyl]-8-Quinolinol Core Structure That Activates p53. PLoS One. 2016; 11(4):e0154125.
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An interconnected hierarchical model of cell death regulation by the BCL-2 family. Nat Cell Biol. 2015 Oct; 17(10):1270-81.
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P38a MAPK underlies muscular dystrophy and myofiber death through a Bax-dependent mechanism. Hum Mol Genet. 2014 Oct 15; 23(20):5452-63.