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Chin-Tu Chen

TitleAssociate Professor
InstitutionUniversity of Chicago
DepartmentRadiology
AddressChicago IL 60637
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    Collapse Overview 
    Collapse overview
    Dr. Chen's research interests, primarily in integrative multi-modality molecular imaging, cover a broad spectrum of imaging-centered topics including imaging physics and instrumentation, image reconstruction and processing, imaging tracers and probes development, physiological modeling, quantitative and intelligent image analysis, as well as applications of molecular imaging methods in a wide spectrum of biological and medical investigations, especially in cancer, brain disorders, cardiopulmonary diseases, and diabetes.


    Collapse Biography 
    Collapse education and training
    National Tsing-Hua University, Hsinchu, TaiwanBS06/1974Physics
    Northwester University, Evanston, IllinoisMS06/1978Physics
    The University of Chicago, Chicago, IllinoisPhD12/1986Medical Physics

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Brugarolas P, Sánchez-Rodríguez JE, Tsai HM, Basuli F, Cheng SH, Zhang X, Caprariello AV, Lacroix JJ, Freifelder R, Murali D, DeJesus O, Miller RH, Swenson RE, Chen CT, Herscovitch P, Reich DS, Bezanilla F, Popko B. Development of a PET radioligand for potassium channels to image CNS demyelination. Sci Rep. 2018 01 12; 8(1):607. PMID: 29330383.
      View in: PubMed
    2. Quigley BP, Smith CD, Cheng SH, Souris JS, Pelizzari CA, Chen CT, Lo LW, Reft CS, Wiersma RD, La Riviere PJ. Sensitivity evaluation and selective plane imaging geometry for x-ray-induced luminescence imaging. Med Phys. 2017 Oct; 44(10):5367-5377. PMID: 28703922.
      View in: PubMed
    3. Chen NT, Souris JS, Cheng SH, Chu CH, Wang YC, Konda V, Dougherty U, Bissonnette M, Mou CY, Chen CT, Lo LW. Lectin-functionalized mesoporous silica nanoparticles for endoscopic detection of premalignant colonic lesions. Nanomedicine. 2017 Aug; 13(6):1941-1952. PMID: 28363770.
      View in: PubMed
    4. Cheng SH, Yu D, Tsai HM, Morshed RA, Kanojia D, Lo LW, Leoni L, Govind Y, Zhang L, Aboody KS, Lesniak MS, Chen CT, Balyasnikova IV. Dynamic In Vivo SPECT Imaging of Neural Stem Cells Functionalized with Radiolabeled Nanoparticles for Tracking of Glioblastoma. J Nucl Med. 2016 Feb; 57(2):279-84. PMID: 26564318.
      View in: PubMed
    5. Lennon FE, Cianci GC, Cipriani NA, Hensing TA, Zhang HJ, Chen CT, Murgu SD, Vokes EE, Vannier MW, Salgia R. Lung cancer-a fractal viewpoint. Nat Rev Clin Oncol. 2015 Nov; 12(11):664-75. PMID: 26169924.
      View in: PubMed
    6. Souris JS, Cheng SH, Pelizzari C, Chen NT, La Riviere P, Chen CT, Lo LW. Radioluminescence characterization of in situ x-ray nanodosimeters: Potential real-time monitors and modulators of external beam radiation therapy. Appl Phys Lett. 2014 Nov 17; 105(20):203110. PMID: 25425747.
      View in: PubMed
    7. Makinen MW, Bamba R, Ikejimba L, Wietholt C, Chen CT, Conzen SD. The vanadyl chelate bis(acetylacetonato)oxovanadium(IV) increases the fractional uptake of 2-(fluorine-18)-2-deoxy-D-glucose by cultured human breast carcinoma cells. Dalton Trans. 2013 Sep 07; 42(33):11862-7. PMID: 23644715.
      View in: PubMed
    8. Cheng Y, Morshed R, Cheng SH, Tobias A, Auffinger B, Wainwright DA, Zhang L, Yunis C, Han Y, Chen CT, Lo LW, Aboody KS, Ahmed AU, Lesniak MS. Nanoparticle-programmed self-destructive neural stem cells for glioblastoma targeting and therapy. Small. 2013 Dec 20; 9(24):4123-9. PMID: 23873826.
      View in: PubMed
    9. Ryan JJ, Marsboom G, Fang YH, Toth PT, Morrow E, Luo N, Piao L, Hong Z, Ericson K, Zhang HJ, Han M, Haney CR, Chen CT, Sharp WW, Archer SL. PGC1a-mediated mitofusin-2 deficiency in female rats and humans with pulmonary arterial hypertension. Am J Respir Crit Care Med. 2013 Apr 15; 187(8):865-78. PMID: 23449689.
      View in: PubMed
    10. Souris JS, Hickson JA, Msezane L, Rinker-Schaeffer CW, Chen CT. Flexible peritoneal windows for quantitative fluorescence and bioluminescence preclinical imaging. Mol Imaging. 2013 Jan-Feb; 12(1):28-38. PMID: 23348789.
      View in: PubMed
    11. Marsboom G, Wietholt C, Haney CR, Toth PT, Ryan JJ, Morrow E, Thenappan T, Bache-Wiig P, Piao L, Paul J, Chen CT, Archer SL. Lung ¹8F-fluorodeoxyglucose positron emission tomography for diagnosis and monitoring of pulmonary arterial hypertension. Am J Respir Crit Care Med. 2012 Mar 15; 185(6):670-9. PMID: 22246173.
      View in: PubMed
    12. Liao S, Penney BC, Wroblewski K, Zhang H, Simon CA, Kampalath R, Shih MC, Shimada N, Chen S, Salgia R, Appelbaum DE, Suzuki K, Chen CT, Pu Y. Prognostic value of metabolic tumor burden on 18F-FDG PET in nonsurgical patients with non-small cell lung cancer. Eur J Nucl Med Mol Imaging. 2012 Jan; 39(1):27-38. PMID: 21946983.
      View in: PubMed
    13. Mathew B, Lennon FE, Siegler J, Mirzapoiazova T, Mambetsariev N, Sammani S, Gerhold LM, LaRiviere PJ, Chen CT, Garcia JG, Salgia R, Moss J, Singleton PA. The novel role of the mu opioid receptor in lung cancer progression: a laboratory investigation. Anesth Analg. 2011 Mar; 112(3):558-67. PMID: 21156980.
      View in: PubMed
    14. Mathew B, Huang Y, Jacobson JR, Berdyshev E, Gerhold LM, Wang T, Moreno-Vinasco L, Lang G, Zhao Y, Chen CT, LaRiviere PJ, Mauceri H, Sammani S, Husain AN, Dudek SM, Natarajan V, Lussier YA, Weichselbaum RR, Garcia JG. Simvastatin attenuates radiation-induced murine lung injury and dysregulated lung gene expression. Am J Respir Cell Mol Biol. 2011 Mar; 44(3):415-22. PMID: 20508068.
      View in: PubMed
    15. Souris JS, Lee CH, Cheng SH, Chen CT, Yang CS, Ho JA, Mou CY, Lo LW. Surface charge-mediated rapid hepatobiliary excretion of mesoporous silica nanoparticles. Biomaterials. 2010 Jul; 31(21):5564-74. PMID: 20417962.
      View in: PubMed
    16. Cho S, Bian J, Pelizzari CA, Chen CT, He TC, Pan X. Region-of-interest image reconstruction in circular cone-beam microCT. Med Phys. 2007 Dec; 34(12):4923-33. PMID: 18196817.
      View in: PubMed
    17. Kao CM, Pan X, Chen CT. An exact Fourier rebinning algorithm for 3D PET imaging using panel detectors. Phys Med Biol. 2004 Jun 07; 49(11):2407-23. PMID: 15248586.
      View in: PubMed
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