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Graeme Bell

TitleProfessor
InstitutionUniversity of Chicago
DepartmentMedicine-Endocrinology
AddressChicago IL 60637
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    Collapse Overview 
    Collapse overview
    Dr. Bell's research program focuses on the genetics of diabetes and other metabolic disorders.

    Collapse Biography 
    Collapse education and training
    University of Calgary, Calgary, CanadaB.Sc.06/1968Zoology
    University of Calgary, Calgary, CanadaM.Sc.06/1971Biology
    University of California San Francisco, San FranciscoPh.D.01/1977Biochemistry
    Collapse awards and honors
    2016 - PresKovler Family Distinguished Service Professor, The University of Chicago
    1998National Academy of Medicine
    2008American Academy of Arts and Sciences
    2011Fellow of the American Association of the Advancement of Science
    2012Manpei Suzuki International Prize for Diabetes Research
    2013The Banting Medal for Scientific Achievement of the American Diabetes Association

    Collapse Research 
    Collapse research activities and funding
    R01GM114289     (KREITMAN, MARTIN E)Apr 1, 2015 - Dec 31, 2018
    NIH
    A Fly Model of Complex Protein Misfolding Disease
    Role: Co-Principal Investigator
    R01DK093972     (NOBREGA, MARCELO A.)Sep 25, 2012 - Jul 31, 2015
    NIH
    Functional follow-up of the association between TCF7L2 and T2D
    Role: Co-Principal Investigator
    R01DK068766     (BELL, GRAEME I)Jul 1, 2004 - Jun 30, 2007
    NIH
    Transcriptional Regulatory Networks in Pancreatic Islets
    Role: Principal Investigator
    P30DK020595     (BELL, GRAEME I)Dec 1, 1996 - Mar 31, 2023
    NIH
    Diabetes Research and Training Center
    Role: Principal Investigator
    R01DK047486     (BELL, GRAEME I)Sep 30, 1993 - Aug 31, 2006
    NIH
    GENES FOR NON-INSULIN-DEPENDENT DIABETES MELLITUS
    Role: Principal Investigator
    R01DK046627     (BELL, GRAEME I)May 1, 1993 - Apr 30, 1998
    NIH
    GENES RESPONSIBLE IN INSULIN-DEPENDENT DIABETES MELLITUS
    Role: Principal Investigator
    P01DK044840     (BELL, GRAEME I)May 1, 1992 - Nov 30, 2003
    NIH
    MOLECULAR MECHANISMS/BETA CELL DYSFUNCTION IN DIABETES
    Role: Principal Investigator
    P60DK020595     (BELL, GRAEME I)Sep 1, 1977 - Feb 28, 2013
    NIH
    Diabetes Research and Training Center
    Role: Principal Investigator
    T32DK007011     (BELL, GRAEME I;MIRMIRA, RAGHAVENDRA G)Jul 1, 1975 - Jun 30, 2026
    NIH
    Integrated Clinical and Basic Endocrinology Research
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Bowden TL, Letourneau-Freiberg LR, Kandasamy B, Sanyoura M, Tian P, Harris AG, Bell GI, Philipson LH, Naylor RN, Greeley SAW. Insight on Diagnosis and Treatment From Over a Decade of Research Through the University of Chicago Monogenic Diabetes Registry. Front Clin Diabetes Healthc. 2021 Nov; 2. PMID: 36330312; PMCID: PMC9629510.
      Citations: 3     
    2. De Franco E, Ye H, Park SY, Bell GI, Hattersley AT, Støy J. In celebration of a century with insulin - Update of insulin gene mutations in diabetes. Mol Metab. 2021 10; 52:101280. PMID: 34174481; PMCID: PMC8513141.
      Citations: 10     Fields:    Translation:HumansCells
    3. Flannick J, Mercader JM, Fuchsberger C, Udler MS, Mahajan A, Wessel J, Teslovich TM, Caulkins L, Koesterer R, Blackwell TW, Boerwinkle E, Brody JA, Chen L, Chen S, Correa A, Cortes M, DeFronzo RA, Dolan L, Drews KL, Elliott A, Floyd JS, Gabriel S, Garay-Sevilla ME, Gross M, Han S, Heard-Costa NL, Jackson AU, Kang HM, Kelsey M, Kim BJ, Koistinen HA, Kuusisto J, Leader JB, Linneberg A, Liu CT, Liu J, Manning AK, Marcketta A, Malacara-Hernandez JM, Matsuo K, Mayer-Davis E, Mohlke KL, Morrison AC, Ndungu A, Ng MCY, O'Dushlaine C, Payne AJ, Pihoker C, Broad Genomics Platform, Post WS, Preuss M, Psaty BM, Vasan RS, Rayner NW, Reiner AP, Revilla-Monsalve C, Robertson NR, Santoro N, Schurmann C, So WY, Stringham HM, Tam CHT, Thameem F, Tomlinson B, Torres JM, Tracy RP, van Dam RM, Vujkovic M, Wang S, Welch RP, Witte DR, Wong TY, Atzmon G, Barzilai N, Blangero J, Bonnycastle LL, Bowden DW, Chambers JC, Chan E, Cheng CY, Cho YS, Collins FS, de Vries PS, Duggirala R, Glaser B, Gonzalez ME, Kooner JS, Kwak SH, Laakso M, Lehman DM, Spector TD, Tai ES, Tuomi T, Tuomilehto J, Wilson JG, Aguilar-Salinas CA, Bottinger E, Burke B, Carey DJ, Chan JCN, Frossard P, Heckbert SR, Hwang MY, Kim YJ, Kirchner HL, Lee JY, Lee J, Loos RJF, Ma RCW, Morris AD, O'Donnell CJ, Palmer CNA, Pankow J, Park KS, Rasheed A, Saleheen D, Sim X, Small KS, Teo YY, Haiman C, Hanis CL, Henderson BE, Dewey FE, Baras A, Lange L, Grarup N, Hansen T, Pedersen O, Zeitler P, Dabelea D, Abecasis G, Bell GI, Cox NJ, Seielstad M, Sladek R, Meigs JB, Rich SS, Rotter JI, DiscovEHR Collaboration, CHARGE, LuCamp, ProDiGY, GoT2D, ESP, SIGMA-T2D, T2D-GENES, AMP-T2D-GENES, Altshuler D, Scott LJ, Morris AP, Florez JC, McCarthy MI, Boehnke M, Barajas-Olmos F, Centeno-Cruz F, Contreras-Cubas C, Córdova E, García-Ortiz H, Jørgensen ME, Lyssenko V, Martínez-Hernández A, Mendoza-Caamal E, Soberón X, Strom TM, Gonzalez C, Groop L, Nilsson P, Dupuis J, Orozco L, Tusié-Luna T, Gieger C, Meitinger T, Strauch K, Burtt NP. Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls. Nature. 2019 06; 570(7759):71-76. PMID: 31118516; PMCID: PMC6699738.
      Citations: 137     Fields:    Translation:HumansAnimals
    4. Petty LE, Highland HM, Gamazon ER, Hu H, Karhade M, Chen HH, de Vries PS, Grove ML, Aguilar D, Bell GI, Huff CD, Hanis CL, Doddapaneni H, Munzy DM, Gibbs RA, Ma J, Parra EJ, Arking DE, Barbeira A, Im HK, Morrison AC, Boerwinkle E, Below JE, Cruz M, Valladares-Salgado A. Functionally oriented analysis of cardiometabolic traits in a trans-ethnic sample. Hum Mol Genet. 2019 04 01; 28(7):1212-1224. PMID: 30624610; PMCID: PMC6423424.
      Citations: 9     Fields:    Translation:HumansCells
    5. Collins J, Simpson KMJ, Bell G, Durrheim DN, Hill-Cawthorne GA, Hope K, Howard P, Kohlenberg T, Lawrence K, Lilly K, Porigneaux P, Sintchenko V, Wang Q, Ward MP, Wiethoelter A, Mor SM, Flint J. A One Health investigation of Salmonella enterica serovar Wangata in north-eastern New South Wales, Australia, 2016-2017. Epidemiol Infect. 2019 01; 147:e150. PMID: 30869062; PMCID: PMC6518825.
      Citations: 7     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    6. Goel V, Islam MS, Yunus M, Ali MT, Khan AF, Alam N, Faruque ASG, Bell G, Sobsey M, Emch M. Deep tubewell microbial water quality and access in arsenic mitigation programs in rural Bangladesh. Sci Total Environ. 2019 Apr 01; 659:1577-1584. PMID: 31096367; PMCID: PMC6724724.
      Citations: 2     Fields:    Translation:HumansPHPublic Health
    7. Walker AV, Gelb LD, Barry GE, Subanajouy P, Poudel A, Hara M, Veryovkin IV, Bell GI, Hanley L. Femtosecond laser desorption ionization mass spectrometry imaging and multivariate analysis of lipids in pancreatic tissue. Biointerphases. 2018 04 02; 13(3):03B416. PMID: 29609468; PMCID: PMC5880676.
      Citations: 4     Fields:    Translation:Humans
    8. Chen H, Cade BE, Gleason KJ, Bjonnes AC, Stilp AM, Sofer T, Conomos MP, Ancoli-Israel S, Arens R, Azarbarzin A, Bell GI, Below JE, Chun S, Evans DS, Ewert R, Frazier-Wood AC, Gharib SA, Hagen EW, Heinzer R, Hillman DR, Johnson WC, Kutalik Z, Lane JM, Larkin EK, Lee SK, Liang J, Loredo JS, Mukherjee S, Palmer LJ, Papanicolaou GJ, Peppard PE, Post WS, Ramos AR, Rice K, Rotter JI, Sands SA, Shah NA, Shin C, Stone KL, Stubbe B, Sul JH, Tafti M, Taylor KD, Teumer A, Thornton TA, Tranah GJ, Wang C, Wang H, Warby SC, Wellman DA, Zee PC, Hanis CL, Laurie CC, Gottlieb DJ, Patel SR, Zhu X, Sunyaev SR, Saxena R, Lin X, Redline S, Haba-Rubio J, Penzel T. Multiethnic Meta-Analysis Identifies RAI1 as a Possible Obstructive Sleep Apnea-related Quantitative Trait Locus in Men. Am J Respir Cell Mol Biol. 2018 03; 58(3):391-401. PMID: 29077507; PMCID: PMC5854957.
      Citations: 33     Fields:    Translation:Humans
    9. Flannick J, Fuchsberger C, Mahajan A, Teslovich TM, Agarwala V, Gaulton KJ, Caulkins L, Koesterer R, Ma C, Moutsianas L, McCarthy DJ, Rivas MA, Perry JRB, Sim X, Blackwell TW, Robertson NR, Rayner NW, Cingolani P, Locke AE, Tajes JF, Highland HM, Dupuis J, Chines PS, Lindgren CM, Hartl C, Jackson AU, Chen H, Huyghe JR, van de Bunt M, Pearson RD, Kumar A, Grarup N, Stringham HM, Gamazon ER, Lee J, Chen Y, Scott RA, Below JE, Chen P, Huang J, Go MJ, Stitzel ML, Pasko D, Parker SCJ, Varga TV, Green T, Beer NL, Day-Williams AG, Ferreira T, Fingerlin T, Horikoshi M, Hu C, Huh I, Ikram MK, Kim BJ, Kim Y, Kim YJ, Kwon MS, Lee J, Lee S, Lin KH, Maxwell TJ, Nagai Y, Wang X, Welch RP, Yoon J, Zhang W, Barzilai N, Voight BF, Han BG, Jenkinson CP, Kuulasmaa T, Kuusisto J, Manning A, Ng MCY, Palmer ND, Balkau B, Abboud HE, Boeing H, Giedraitis V, Prabhakaran D, Gottesman O, Scott J, Carey J, Kwan P, Grant G, Smith JD, Neale BM, Purcell S, Butterworth AS, Howson JMM, Lee HM, Lu Y, Kwak SH, Zhao W, Danesh J, Lam VKL, Park KS, Saleheen D, So WY, Tam CHT, Afzal U, Aguilar D, Arya R, Aung T, Chan E, Navarro C, Cheng CY, Palli D, Correa A, Curran JE, Rybin D, Farook VS, Fowler SP, Freedman BI, Griswold M, Hale DE, Hicks PJ, Khor CC, Kumar S, Lehne B, Lim WY, Liu J, Loh M, Musani SK, Puppala S, Scott WR, Tan ST, Taylor HA, Thameem F, Wilson G, Wong TY, Levy JC, Mangino M, Bonnycastle LL, Schwarzmayr T, Surdulescu GL, Herder C, Groves CJ, Wieland T, Bork-Jensen J, Brandslund I, Christensen C, Koistinen HA, Doney ASF, Kinnunen L, Farmer AJ, Hakaste L, Hodgkiss D, Kravic J, Lyssenko V, Hollensted M, Ladenvall C, Justesen JM, Kriebel J, Rathmann W, Lannfelt L, Lauritzen T, Narisu N, Linneberg A, Melander O, Milani L, Neville M, Orho-Melander M, Qi L, Qi Q, Roden M, Rolandsson O, Swift A, Rosengren AH, Stirrups K, Wood AR, Mihailov E, Blancher C, Carneiro MO, Maguire J, Poplin R, Shakir K, Fennell T, DePristo M, Deloukas P, Gjesing AP, Jun G, Nilsson P, Murphy J, Onofrio R, Thorand B, Hansen T, Meisinger C, Hu FB, Isomaa B, Karpe F, Liang L, Peters A, Huth C, O'Rahilly SP, Palmer CNA, Pedersen O, Rauramaa R, Tuomilehto J, Salomaa V, Watanabe RM, Bergman RN, Bharadwaj D, Bottinger EP, Cho YS, Chandak GR, Chan JCN, Chia KS, Daly MJ, Ebrahim SB, Langenberg C, Elliott P, Jablonski KA, Lehman DM, Jia W, Ma RCW, Pollin TI, Sandhu M, Tandon N, Froguel P, Teo YY, Zeggini E, Loos RJF, Small KS, Ried JS, DeFronzo RA, Grallert H, Glaser B, Metspalu A, Wareham NJ, Walker M, Banks E, Gieger C, Ingelsson E, Im HK, Illig T, Franks PW, Buck G, Trakalo J, Buck D, Prokopenko I, Lind L, Farjoun Y, Owen KR, Gloyn AL, Strauch K, Tuomi T, Kooner JS, Lee JY, Park T, Donnelly P, Morris AD, Hattersley AT, Bowden DW, Collins FS, Atzmon G, Chambers JC, Spector TD, Laakso M, Strom TM, Bell GI, Blangero J, Duggirala R, Tai ES, McVean G, Hanis CL, Wilson JG, Seielstad M, Frayling TM, Meigs JB, Cox NJ, Sladek R, Lander ES, Gabriel S, Mohlke KL, Meitinger T, Groop L, Abecasis G, Scott LJ, Morris AP, Kang HM, Altshuler D, Florez JC, Boehnke M, McCarthy MI, Müller-Nurasyid M, Stancáková A, Thuillier D, Yengo L, Njølstad PR, Fadista J, Esko T, Jørgensen ME, Jørgensen T, Käräjämäki A, de Angelis MH, Syvänen AC, Barroso I, Mägi R, Burtt NP. Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. Sci Data. 2018 01 23; 5:180002. PMID: 29360107; PMCID: PMC5779067.
      Citations: 1     Fields:    
    10. Jun G, Manning A, Almeida M, Zawistowski M, Wood AR, Teslovich TM, Fuchsberger C, Feng S, Gaulton KJ, Dyer T, Blackwell TW, Chen H, Chines PS, Choi S, Churchhouse C, Fontanillas P, King R, Lee S, Lincoln SE, Trubetskoy V, DePristo M, Fingerlin T, Grossman R, Grundstad J, Heath A, Kim J, Kim YJ, Laramie J, Lee J, Li H, Liu X, Livne O, Locke AE, Maller J, Morris AP, Pollin TI, Ragona D, Reich D, Rivas MA, Scott LJ, Sim X, Tearle RG, Teo YY, Williams AL, Curran JE, Peralta J, Akolkar B, Bell GI, Cox NJ, Florez JC, Hanis CL, McKeon C, Mohlke KL, Seielstad M, Wilson JG, Atzmon G, Below JE, Nicolae DL, Lehman D, Park T, Won S, Altshuler D, McCarthy MI, Duggirala R, Boehnke M, Frayling TM, Blangero J, Cingolani P, Mazur A, Zöllner S, Burtt NP, Dupuis J, Sladek R, Abecasis GR. Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees. Proc Natl Acad Sci U S A. 2018 01 09; 115(2):379-384. PMID: 29279374; PMCID: PMC5777025.
      Citations: 21     Fields:    Translation:Humans
    11. Flannick J, Fuchsberger C, Mahajan A, Teslovich TM, Agarwala V, Gaulton KJ, Caulkins L, Koesterer R, Ma C, Moutsianas L, McCarthy DJ, Rivas MA, Perry JRB, Sim X, Blackwell TW, Robertson NR, Rayner NW, Cingolani P, Locke AE, Tajes JF, Highland HM, Dupuis J, Chines PS, Lindgren CM, Hartl C, Jackson AU, Chen H, Huyghe JR, van de Bunt M, Pearson RD, Kumar A, Grarup N, Stringham HM, Gamazon ER, Lee J, Chen Y, Scott RA, Below JE, Chen P, Huang J, Go MJ, Stitzel ML, Pasko D, Parker SCJ, Green T, Beer NL, Day-Williams AG, Ferreira T, Fingerlin T, Horikoshi M, Hu C, Huh I, Ikram MK, Kim BJ, Kim Y, Kim YJ, Kwon MS, Lee J, Lee S, Lin KH, Maxwell TJ, Wang X, Welch RP, Yoon J, Zhang W, Barzilai N, Voight BF, Han BG, Jenkinson CP, Kuulasmaa T, Kuusisto J, Manning A, Ng MCY, Palmer ND, Balkau B, Abboud HE, Boeing H, Giedraitis V, Prabhakaran D, Gottesman O, Scott J, Carey J, Kwan P, Grant G, Smith JD, Neale BM, Purcell S, Butterworth AS, Howson JMM, Lee HM, Lu Y, Kwak SH, Zhao W, Danesh J, Lam VKL, Park KS, Saleheen D, So WY, Tam CHT, Afzal U, Aguilar D, Arya R, Aung T, Chan E, Navarro C, Cheng CY, Palli D, Correa A, Curran JE, Rybin D, Farook VS, Fowler SP, Freedman BI, Griswold M, Hale DE, Hicks PJ, Khor CC, Kumar S, Lehne B, Lim WY, Liu J, Loh M, Musani SK, Puppala S, Scott WR, Tan ST, Taylor HA, Thameem F, Wilson G, Wong TY, Levy JC, Mangino M, Bonnycastle LL, Surdulescu GL, Groves CJ, Bork-Jensen J, Brandslund I, Christensen C, Koistinen HA, Doney ASF, Kinnunen L, Farmer AJ, Hakaste L, Hodgkiss D, Hollensted M, Justesen JM, Lannfelt L, Lauritzen T, Narisu N, Linneberg A, Milani L, Neville M, Qi L, Qi Q, Swift A, Stirrups K, Wood AR, Mihailov E, Blancher C, Carneiro MO, Maguire J, Poplin R, Shakir K, Fennell T, DePristo M, Deloukas P, Gjesing AP, Jun G, Murphy J, Onofrio R, Hansen T, Hu FB, Karpe F, Liang L, Peters A, O'Rahilly SP, Palmer CNA, Pedersen O, Rauramaa R, Tuomilehto J, Salomaa V, Watanabe RM, Bergman RN, Bharadwaj D, Bottinger EP, Cho YS, Chandak GR, Chan JC, Chia KS, Daly MJ, Ebrahim SB, Langenberg C, Elliott P, Jablonski KA, Lehman DM, Jia W, Ma RCW, Pollin TI, Sandhu M, Tandon N, Froguel P, Teo YY, Zeggini E, Loos RJF, Small KS, DeFronzo RA, Glaser B, Metspalu A, Wareham NJ, Walker M, Banks E, Ingelsson E, Im HK, Buck G, Trakalo J, Buck D, Prokopenko I, Lind L, Farjoun Y, Owen KR, Gloyn AL, Tuomi T, Kooner JS, Lee JY, Park T, Donnelly P, Morris AD, Hattersley AT, Bowden DW, Collins FS, Atzmon G, Chambers JC, Spector TD, Laakso M, Bell GI, Blangero J, Duggirala R, Tai ES, McVean G, Hanis CL, Wilson JG, Seielstad M, Frayling TM, Meigs JB, Cox NJ, Lander ES, Gabriel S, Mohlke KL, Abecasis G, Scott LJ, Morris AP, Kang HM, Altshuler D, Florez JC, Boehnke M, McCarthy MI, Müller-Nurasyid M, Varga TV, Nagai Y, Stancáková A, Thuillier D, Yengo L, Njølstad PR, Schwarzmayr T, Fadista J, Herder C, Wieland T, Esko T, Kravic J, Lyssenko V, Jørgensen ME, Jørgensen T, Ladenvall C, Käräjämäki A, Kriebel J, Rathmann W, Melander O, Orho-Melander M, Roden M, Rolandsson O, Rosengren AH, de Angelis MH, Nilsson P, Thorand B, Meisinger C, Isomaa B, Huth C, Syvänen AC, Barroso I, Ried JS, Grallert H, Gieger C, Illig T, Franks PW, Mägi R, Strauch K, Strom TM, Sladek R, Meitinger T, Groop L, Burtt NP. Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. Sci Data. 2017 12 19; 4:170179. PMID: 29257133; PMCID: PMC5735917.
      Citations: 17     Fields:    Translation:Humans
    12. Mercader JM, Liao RG, Bell AD, Dymek Z, Estrada K, Tukiainen T, Jablonski KA, Hanson RL, Walford GA, Moran I, Chen L, Agarwala V, Caulkins L, Puppala S, Fontanillas P, Williams AL, Hartl C, Ripke S, Diabetes Prevention Program Research Group, Tooley K, Lane J, Henderson BE, Wilkens LR, Le Marchand L, Harden M, Broad Genomics Platform, Gabriel S, T2D-GENES Consortium, Abboud HE, Cortes ML, Curran JE, Jenkinson CP, DeFronzo RA, Lehman DM, Hanis CL, Bell GI, Boehnke M, Blangero J, Duggirala R, Saxena R, MacArthur D, Ferrer J, McCarroll SA, Torrents D, Knowler WC, Baier LJ, Burtt N, Haiman CA, Flannick J, Jacobs SBR, Altshuler D, Florez JC, SIGMA T2D Genetics Consortium, Huerta-Chagoya A, Moreno-Macías H, Ordoñez-Sánchez ML, Rodríguez-Guillen R, Rodríguez-Torres M, Segura-Kato Y, García-Ortiz H, Centeno-Cruz F, Barajas-Olmos F, Bonàs-Guarch S, Zerrweck C, Martínez-Hernández A, Córdova EJ, Mendoza-Caamal E, Contreras-Cubas C, González-Villalpando ME, Cruz-Bautista I, Muñoz-Hernández L, Gómez-Velasco D, Alvirde U, Arellano-Campos O, Riba L, Revilla-Monsalve C, Islas-Andrade S, Soberon X, González-Villalpando C, Aguilar-Salinas CA, Tusié-Luna T, Orozco L. A Loss-of-Function Splice Acceptor Variant in IGF2 Is Protective for Type 2 Diabetes. Diabetes. 2017 11; 66(11):2903-2914. PMID: 28838971; PMCID: PMC5652606.
      Citations: 22     Fields:    Translation:HumansCells
    13. Park SY, Bell GI, Støy J, Olsen J, Gregersen S, Hjørringgaard CU. In vivo measurement and biological characterisation of the diabetes-associated mutant insulin p.R46Q (GlnB22-insulin). Diabetologia. 2017 08; 60(8):1423-1431. PMID: 28478482; PMCID: PMC8785399.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    14. Manning A, Highland HM, Gasser J, Sim X, Tukiainen T, Fontanillas P, Grarup N, Rivas MA, Mahajan A, Locke AE, Cingolani P, Pers TH, Brown AA, Wu Y, Flannick J, Fuchsberger C, Gamazon ER, Gaulton KJ, Im HK, Teslovich TM, Blackwell TW, Bork-Jensen J, Chen Y, Green T, Hartl C, Kang HM, Kumar A, Ma C, Moutsianas L, Pearson RD, Perry JRB, Rayner NW, Robertson NR, Scott LJ, van de Bunt M, Eriksson JG, Jula A, Koskinen S, Palotie A, Raitakari OT, Jacobs SBR, Wessel J, Chu AY, Scott RA, Goodarzi MO, Blancher C, Buck G, Buck D, Chines PS, Gabriel S, Gjesing AP, Groves CJ, Hollensted M, Huyghe JR, Jackson AU, Jun G, Justesen JM, Mangino M, Murphy J, Neville M, Onofrio R, Small KS, Stringham HM, Trakalo J, Banks E, Carey J, Carneiro MO, DePristo M, Farjoun Y, Fennell T, Goldstein JI, Grant G, Maguire J, Neale BM, Poplin R, Purcell S, Shakir K, Smith JD, Lindstrom J, Brandslund I, Christensen C, Surdulescu GL, Lakka TA, Doney ASF, Wareham NJ, Langenberg C, Farook VS, Thameem F, Puppala S, Kumar S, Lehman DM, Jenkinson CP, Curran JE, Hale DE, Fowler SP, Arya R, DeFronzo RA, Abboud HE, Hicks PJ, Palmer ND, Ng MCY, Bowden DW, Freedman BI, Milani L, Mihailov E, Metspalu A, Narisu N, Kinnunen L, Bonnycastle LL, Swift A, Pasko D, Wood AR, Pollin TI, Barzilai N, Atzmon G, Glaser B, Thorand B, Peters A, Liang L, Kriebel J, Grallert H, Lannfelt L, Musani SK, Griswold M, Taylor HA, Wilson G, Correa A, Oksa H, Scott WR, Afzal U, Tan ST, Loh M, Chambers JC, Sehmi J, Kooner JS, Lehne B, Cho YS, Lee JY, Han BG, Qi Q, Qi L, Huang J, Hu FB, Below JE, Aguilar D, Wong TY, Liu J, Khor CC, Chia KS, Lim WY, Cheng CY, Chan E, Tai ES, Aung T, Linneberg A, Lauritzen T, Deloukas P, Stirrups KE, Owen KR, Farmer AJ, Frayling TM, O'Rahilly SP, Walker M, Levy JC, Hodgkiss D, Hattersley AT, Kuulasmaa T, Bharadwaj D, Chan J, Chandak GR, Daly MJ, Donnelly PJ, Ebrahim SB, Elliott P, Fingerlin T, Froguel P, Hu C, Jia W, Ma RCW, McVean G, Park T, Prabhakaran D, Sandhu M, Scott J, Tandon N, Teo YY, Zeggini E, Watanabe RM, Koistinen HA, Kesaniemi YA, Uusitupa M, Spector TD, Salomaa V, Rauramaa R, Palmer CNA, Prokopenko I, Morris AD, Bergman RN, Collins FS, Lind L, Ingelsson E, Tuomilehto J, Karpe F, Hansen T, Pedersen O, Kuusisto J, Bell GI, Blangero J, Cox NJ, Duggirala R, Seielstad M, Wilson JG, Dupuis J, Ripatti S, Hanis CL, Florez JC, Mohlke KL, Meigs JB, Laakso M, Morris AP, Boehnke M, Altshuler D, McCarthy MI, Gloyn AL, Lindgren CM, Viñuela A, Burtt NP, Ladenvall C, Lehtimäki T, Hrabé de Angelis M, Schwarzmayr T, Strom TM, Wieland T, Nilsson P, Varga TV, Franks PW, Rolandsson O, Rosengren AH, Syvänen AC, Esko T, Mägi R, Fadista J, Strauch K, Roden M, Müller-Nurasyid M, Illig T, Gieger C, Meisinger C, Käräjämäki A, Melander O, Orho-Melander M, Isomaa B, Meitinger T, Tuomi T, Hakaste L, Kravic J, Jørgensen ME, Stancáková A, Barroso I, Sladek R, Groop L, Jørgensen T, Abecasis G. A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk. Diabetes. 2017 07; 66(7):2019-2032. PMID: 28341696; PMCID: PMC5482074.
      Citations: 28     Fields:    Translation:Humans
    15. Cade BE, Chen H, Stilp AM, Gleason KJ, Sofer T, Ancoli-Israel S, Arens R, Bell GI, Below JE, Bjonnes AC, Chun S, Conomos MP, Evans DS, Johnson WC, Frazier-Wood AC, Lane JM, Larkin EK, Loredo JS, Post WS, Ramos AR, Rice K, Rotter JI, Shah NA, Stone KL, Taylor KD, Thornton TA, Tranah GJ, Wang C, Zee PC, Hanis CL, Sunyaev SR, Patel SR, Laurie CC, Zhu X, Saxena R, Lin X, Redline S. Genetic Associations with Obstructive Sleep Apnea Traits in Hispanic/Latino Americans. Am J Respir Crit Care Med. 2016 Oct 01; 194(7):886-897. PMID: 26977737; PMCID: PMC5074655.
      Citations: 61     Fields:    
    16. Fuchsberger C, Flannick J, Teslovich TM, Mahajan A, Agarwala V, Gaulton KJ, Ma C, Fontanillas P, Moutsianas L, McCarthy DJ, Rivas MA, Perry JRB, Sim X, Blackwell TW, Robertson NR, Rayner NW, Cingolani P, Locke AE, Tajes JF, Highland HM, Dupuis J, Chines PS, Lindgren CM, Hartl C, Jackson AU, Chen H, Huyghe JR, van de Bunt M, Pearson RD, Kumar A, Grarup N, Stringham HM, Gamazon ER, Lee J, Chen Y, Scott RA, Below JE, Chen P, Huang J, Go MJ, Stitzel ML, Pasko D, Parker SCJ, Green T, Beer NL, Day-Williams AG, Ferreira T, Fingerlin T, Horikoshi M, Hu C, Huh I, Ikram MK, Kim BJ, Kim Y, Kim YJ, Kwon MS, Lee J, Lee S, Lin KH, Maxwell TJ, Wang X, Welch RP, Yoon J, Zhang W, Barzilai N, Voight BF, Han BG, Jenkinson CP, Kuulasmaa T, Kuusisto J, Manning A, Ng MCY, Palmer ND, Balkau B, Abboud HE, Boeing H, Giedraitis V, Prabhakaran D, Gottesman O, Scott J, Carey J, Kwan P, Grant G, Smith JD, Neale BM, Purcell S, Butterworth AS, Howson JMM, Lee HM, Lu Y, Kwak SH, Zhao W, Danesh J, Lam VKL, Park KS, Saleheen D, So WY, Tam CHT, Afzal U, Aguilar D, Arya R, Aung T, Chan E, Navarro C, Cheng CY, Palli D, Correa A, Curran JE, Rybin D, Farook VS, Fowler SP, Freedman BI, Griswold M, Hale DE, Hicks PJ, Khor CC, Kumar S, Lehne B, Lim WY, Liu J, van der Schouw YT, Loh M, Musani SK, Puppala S, Scott WR, Tan ST, Taylor HA, Thameem F, Wilson G, Wong TY, Levy JC, Mangino M, Bonnycastle LL, Surdulescu GL, Groves CJ, Bork-Jensen J, Brandslund I, Christensen C, Koistinen HA, Doney ASF, Kinnunen L, Farmer AJ, Hakaste L, Hodgkiss D, Hollensted M, Justesen JM, Kriebel J, Lannfelt L, Lauritzen T, Narisu N, Linneberg A, Milani L, Neville M, Qi L, Qi Q, Swift A, Stirrups K, Wood AR, Mihailov E, Blancher C, Carneiro MO, Maguire J, Poplin R, Shakir K, Fennell T, DePristo M, Deloukas P, Gjesing AP, Jun G, Murphy J, Onofrio R, Thorand B, Hansen T, Meisinger C, Hu FB, Karpe F, Liang L, Peters A, Huth C, O'Rahilly SP, Palmer CNA, Pedersen O, Rauramaa R, Tuomilehto J, Salomaa V, Watanabe RM, Bergman RN, Bharadwaj D, Bottinger EP, Cho YS, Chandak GR, Chan JCN, Chia KS, Daly MJ, Ebrahim SB, Langenberg C, Elliott P, Jablonski KA, Lehman DM, Jia W, Ma RCW, Pollin TI, Sandhu M, Tandon N, Froguel P, Teo YY, Zeggini E, Loos RJF, Small KS, DeFronzo RA, Grallert H, Glaser B, Metspalu A, Wareham NJ, Walker M, Banks E, Ingelsson E, Im HK, Buck G, Trakalo J, Buck D, Prokopenko I, Lind L, Farjoun Y, Owen KR, Gloyn AL, Tuomi T, Kooner JS, Lee JY, Park T, Donnelly P, Morris AD, Hattersley AT, Bowden DW, Collins FS, Atzmon G, Chambers JC, Spector TD, Laakso M, Bell GI, Blangero J, Duggirala R, Tai ES, McVean G, Hanis CL, Wilson JG, Seielstad M, Frayling TM, Meigs JB, Cox NJ, Lander ES, Gabriel S, Mohlke KL, Abecasis G, Florez JC, Scott LJ, Morris AP, Kang HM, Boehnke M, Altshuler D, McCarthy MI, Müller-Nurasyid M, Varga TV, Nagai Y, Stancáková A, Thuillier D, Yengo L, Njølstad PR, Schwarzmayr T, Fadista J, Herder C, Wieland T, Esko T, Kravic J, Lyssenko V, Jørgensen ME, Jørgensen T, Ladenvall C, Käräjämäki A, Rathmann W, Melander O, Orho-Melander M, Roden M, Rolandsson O, Rosengren AH, de Angelis MH, Nilsson P, Isomaa B, Syvänen AC, Barroso I, Ried JS, Gieger C, Illig T, Franks PW, Mägi R, Strauch K, Strom TM, Sladek R, Burtt NP, Meitinger T, Groop L. The genetic architecture of type 2 diabetes. Nature. 2016 08 04; 536(7614):41-47. PMID: 27398621; PMCID: PMC5034897.
      Citations: 513     Fields:    Translation:Humans
    17. Hanis CL, Redline S, Cade BE, Bell GI, Cox NJ, Below JE, Brown EL, Aguilar D. Beyond type 2 diabetes, obesity and hypertension: an axis including sleep apnea, left ventricular hypertrophy, endothelial dysfunction, and aortic stiffness among Mexican Americans in Starr County, Texas. Cardiovasc Diabetol. 2016 Jun 08; 15:86. PMID: 27266869; PMCID: PMC4897940.
      Citations: 24     Fields:    Translation:Humans
    18. Horikoshi M, Wiltshire S, Huyghe JR, Mahajan A, Asimit JL, Ferreira T, Locke AE, Robertson NR, Wang X, Sim X, Fujita H, Hara K, Young R, Zhang W, Choi S, Chen H, Kaur I, Takeuchi F, Fontanillas P, Yengo L, Below JE, Tam CH, Wu Y, Altshuler D, Bell GI, Blangero J, Duggirala R, Florez JC, Hanis CL, Seielstad M, Atzmon G, Chan JC, Ma RC, Froguel P, Wilson JG, Bharadwaj D, Dupuis J, Meigs JB, Cho YS, Park T, Kooner JS, Chambers JC, Saleheen D, Kadowaki T, Tai ES, Mohlke KL, Cox NJ, Zeggini E, Kato N, Teo YY, Boehnke M, McCarthy MI, Morris AP, T2D-GENES Consortium, Pasquali L, Thuillier D, Abecasis G, Burtt NP, Ferrer J. Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms. Hum Mol Genet. 2016 05 15; 25(10):2070-2081. PMID: 26911676; PMCID: PMC5062576.
      Citations: 10     Fields:    Translation:Humans
    19. Hara M, Fowler JL, Bell GI, Philipson LH. Resting beta-cells - A functional reserve? Diabetes Metab. 2016 Jun; 42(3):157-61. PMID: 26827115.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    20. Brown EL, Below JE, Fischer RS, Essigmann HT, Hu H, Huff C, Robinson DA, Petty LE, Aguilar D, Bell GI, Hanis CL. Genome-Wide Association Study of Staphylococcus aureus Carriage in a Community-Based Sample of Mexican-Americans in Starr County, Texas. PLoS One. 2015; 10(11):e0142130. PMID: 26569114; PMCID: PMC4646511.
      Citations: 12     Fields:    Translation:HumansCells
    21. Carmody D, Park SY, Ye H, Perrone ME, Alkorta-Aranburu G, Highland HM, Hanis CL, Philipson LH, Bell GI, Greeley SA. Continued lessons from the INS gene: an intronic mutation causing diabetes through a novel mechanism. J Med Genet. 2015 Sep; 52(9):612-6. PMID: 26101329; PMCID: PMC4744477.
      Citations: 15     Fields:    Translation:Humans
    22. Fahrmann J, Grapov D, Yang J, Hammock B, Fiehn O, Bell GI, Hara M. Systemic alterations in the metabolome of diabetic NOD mice delineate increased oxidative stress accompanied by reduced inflammation and hypertriglyceremia. Am J Physiol Endocrinol Metab. 2015 Jun 01; 308(11):E978-89. PMID: 25852003; PMCID: PMC4451288.
      Citations: 26     Fields:    Translation:AnimalsCells
    23. Mahajan A, Sim X, Ng HJ, Manning A, Rivas MA, Highland HM, Locke AE, Grarup N, Im HK, Flannick J, Fontanillas P, Fuchsberger C, Gaulton KJ, Teslovich TM, Rayner NW, Robertson NR, Beer NL, Rundle JK, Bork-Jensen J, Blancher C, Buck D, Buck G, Gabriel S, Gjesing AP, Groves CJ, Hollensted M, Huyghe JR, Jackson AU, Jun G, Justesen JM, Mangino M, Murphy J, Neville M, Onofrio R, Small KS, Stringham HM, Trakalo J, Abecasis G, Bell GI, Blangero J, Cox NJ, Duggirala R, Hanis CL, Seielstad M, Wilson JG, Christensen C, Brandslund I, Rauramaa R, Surdulescu GL, Doney AS, Lannfelt L, Linneberg A, Kuusisto J, Uusitupa M, Salomaa V, Spector TD, Morris AD, Palmer CN, Collins FS, Mohlke KL, Bergman RN, Ingelsson E, Lind L, Tuomilehto J, Hansen T, Watanabe RM, Prokopenko I, Dupuis J, Karpe F, Laakso M, Pedersen O, Florez JC, Morris AP, Altshuler D, Meigs JB, Boehnke M, McCarthy MI, Lindgren CM, Gloyn AL, T2D-GENES consortium and GoT2D consortium, Cingolani P, Ladenvall C, Burtt NP, Syvänen AC, Isomaa B, Tuomi T, Jørgensen ME, Jørgensen T, Groop L. Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus. PLoS Genet. 2015 Jan; 11(1):e1004876. PMID: 25625282; PMCID: PMC4307976.
      Citations: 60     Fields:    Translation:HumansPHPublic Health
    24. Philipson LH, Bell G, Polonsky KS. Donald F. Steiner MD, 1930-2014: discoverer of proinsulin. Proc Natl Acad Sci U S A. 2015 Jan 27; 112(4):940-1. PMID: 25561547; PMCID: PMC4313841.
      Citations:    Fields:    
    25. Bailey KA, Savic D, Zielinski M, Park SY, Wang LJ, Witkowski P, Brady M, Hara M, Bell GI, Nobrega MA. Evidence of non-pancreatic beta cell-dependent roles of Tcf7l2 in the regulation of glucose metabolism in mice. Hum Mol Genet. 2015 Mar 15; 24(6):1646-54. PMID: 25398947; PMCID: PMC4381752.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    26. SIGMA Type 2 Diabetes Consortium, Estrada K, Aukrust I, Mercader JM, Walford G, Flannick J, Williams AL, Henderson E, Wilkens LR, Le Marchand L, Najmi LA, Jacobs SB, Fennell T, Gabriel S, Fontanillas P, Hanis CL, Lehman DM, Jenkinson CP, Abboud HE, Bell GI, Cortes ML, Boehnke M, Haiman CA, Altshuler D, Florez JC, MacArthur DG, Bjørkhaug L, Burtt NP, García-Ortiz H, Huerta-Chagoya A, Moreno-Macías H, Gómez-Vázquez MJ, Fernandez-Lopez JC, Martínez-Hernández A, Jiménez-Morales S, Centeno-Cruz F, Mendoza-Caamal E, Revilla-Monsalve C, Islas-Andrade S, Córdova EJ, Soberón X, González-Villalpando ME, Arellano-Campos O, Ordóñez-Sánchez ML, Rodríguez-Torres M, Rodríguez-Guillén R, Riba L, González-Villalpando C, Orozco L, Tusié-Luna T, Aguilar-Salinas CA, Njølstad PR. Association of a low-frequency variant in HNF1A with type 2 diabetes in a Latino population. JAMA. 2014 Jun 11; 311(22):2305-14. PMID: 24915262; PMCID: PMC4425850.
      Citations: 116     Fields:    Translation:Humans
    27. Ren D, Sun J, Wang C, Ye H, Mao L, Cheng EH, Bell GI, Polonsky KS. Role of BH3-only molecules Bim and Puma in ß-cell death in Pdx1 deficiency. Diabetes. 2014 Aug; 63(8):2744-50. PMID: 24658302; PMCID: PMC4113059.
      Citations: 14     Fields:    Translation:AnimalsCells
    28. DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium, Asian Genetic Epidemiology Network Type 2 Diabetes (AGEN-T2D) Consortium, South Asian Type 2 Diabetes (SAT2D) Consortium, Mexican American Type 2 Diabetes (MAT2D) Consortium, Type 2 Diabetes Genetic Exploration by Nex-generation sequencing in muylti-Ethnic Samples (T2D-GENES, Mahajan A, Go MJ, Zhang W, Below JE, Gaulton KJ, Ferreira T, Horikoshi M, Johnson AD, Ng MC, Prokopenko I, Saleheen D, Wang X, Zeggini E, Abecasis GR, Adair LS, Almgren P, Atalay M, Aung T, Baldassarre D, Balkau B, Bao Y, Barnett AH, Barroso I, Basit A, Been LF, Beilby J, Bell GI, Benediktsson R, Bergman RN, Boehm BO, Boerwinkle E, Bonnycastle LL, Cai Q, Campbell H, Carey J, Cauchi S, Caulfield M, Chan JC, Chang LC, Chang TJ, Chang YC, Charpentier G, Chen CH, Chen H, Chen YT, Chia KS, Chidambaram M, Chines PS, Cho NH, Cho YM, Chuang LM, Collins FS, Cornelis MC, Couper DJ, Crenshaw AT, van Dam RM, Danesh J, Das D, de Faire U, Dedoussis G, Deloukas P, Dimas AS, Dina C, Doney AS, Donnelly PJ, Dorkhan M, van Duijn C, Edkins S, Elliott P, Emilsson V, Erbel R, Eriksson JG, Escobedo J, Esko T, Eury E, Florez JC, Fontanillas P, Forouhi NG, Forsen T, Fox C, Fraser RM, Frayling TM, Froguel P, Frossard P, Gao Y, Gertow K, Gieger C, Gigante B, Grallert H, Grant GB, Grrop LC, Groves CJ, Grundberg E, Guiducci C, Hamsten A, Han BG, Hara K, Hassanali N, Hattersley AT, Hayward C, Hedman AK, Herder C, Hofman A, Holmen OL, Hovingh K, Hreidarsson AB, Hu C, Hu FB, Hui J, Humphries SE, Hunt SE, Hunter DJ, Hveem K, Hydrie ZI, Ikegami H, Illig T, Ingelsson E, Islam M, Isomaa B, Jackson AU, Jafar T, James A, Jia W, Jonsson A, Jowett JB, Kadowaki T, Kang HM, Kanoni S, Kao WH, Kathiresan S, Kato N, Katulanda P, Keinanen-Kiukaanniemi KM, Kelly AM, Khan H, Khaw KT, Khor CC, Kim HL, Kim S, Kim YJ, Kinnunen L, Klopp N, Kong A, Kowlessur S, Kraft P, Kravic J, Kristensen MM, Krithika S, Kumar A, Kumate J, Kuusisto J, Kwak SH, Laakso M, Lagou V, Lakka TA, Langenberg C, Langford C, Lawrence R, Leander K, Lee JM, Lee NR, Li M, Li X, Li Y, Liang J, Liju S, Lim WY, Lind L, Lindgren CM, Lindholm E, Liu CT, Liu JJ, Long J, Loos RJ, Lu W, Luan J, Lyssenko V, Ma RC, Maeda S, Matthews DR, Meigs JB, Melander O, Metspalu A, Meyer J, Mirza G, Mihailov E, Moebus S, Mohan V, Mohlke KL, Morris AD, Musk B, Nakamura J, Nakashima E, Navarro P, Ng PK, Nica AC, Nilsson PM, Ohnaka K, Ong TH, Owen KR, Palmer CN, Pankow JS, Park KS, Parkin M, Pechlivanis S, Pedersen NL, Peltonen L, Perry JR, Peters A, Pinidiyapathirage JM, Platou CG, Potter S, Price JF, Qi L, Radha V, Rallidis L, Rasheed A, Rathman W, Rauramaa R, Raychaudhuri S, Rayner NW, Rees SD, Rehnberg E, Ripatti S, Robertson N, Roden M, Rossin EJ, Rudan I, Rybin D, Saaristo TE, Salomaa V, Saltevo J, Samuel M, Sanghera DK, Saramies J, Scott J, Scott LJ, Scott RA, Sehmi J, Sennblad B, Shah N, Shah S, Shera AS, Shu XO, Shuldiner AR, Sigurdsson G, Sijbrands E, Silveira A, Sim X, Sivapalaratnam S, Small KS, So WY, Stefansson K, Steinbach G, Steinthorsdottir V, Stirrups K, Strawbridge RJ, Stringham HM, Sun Q, Suo C, Takayanagi R, Takeuchi F, Tay WT, Teslovich TM, Thorand B, Thorleifsson G, Thorsteinsdottir U, Tikkanen E, Trakalo J, Tremoli E, Trip MD, Tsai FJ, Tuomi T, Tuomilehto J, Uitterlinden AG, Valladares-Salgado A, Vedantam S, Veglia F, Voight BF, Wang C, Wareham NJ, Wennauer R, Wickremasinghe AR, Wilsgaard T, Wilson JF, Wiltshire S, Winckler W, Wong TY, Wood AR, Wu JY, Wu Y, Yamamoto K, Yamauchi T, Yang M, Yengo L, Yokota M, Young R, Zabaneh D, Zhang F, Zhang R, Zheng W, Zimmet PZ, Altshuler D, Bowden DW, Cho YS, Cox NJ, Cruz M, Hanis CL, Kooner J, Lee JY, Seielstad M, Teo YY, Boehnke M, Parra EJ, Chambers JC, Tai ES, McCarthy MI, Morris AP, Burtt N, Dupuis J, Jöckel KH, Korpi-Hyövälti E, Lobbens S, Mägi R, Männisto S, Mühleisen TW, Müller-Nurasyid M, Njølstad I, Nöthen MM, Segrè AV, Stancáková A, et al. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet. 2014 Mar; 46(3):234-44. PMID: 24509480; PMCID: PMC3969612.
      Citations: 562     Fields:    Translation:Humans
    29. Park SY, Ludwig MZ, Tamarina NA, He BZ, Carl SH, Dickerson DA, Barse L, Arun B, Williams CL, Miles CM, Philipson LH, Steiner DF, Bell GI, Kreitman M. Genetic complexity in a Drosophila model of diabetes-associated misfolded human proinsulin. Genetics. 2014 Feb; 196(2):539-55. PMID: 24281154; PMCID: PMC3914625.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    30. He BZ, Ludwig MZ, Dickerson DA, Barse L, Arun B, Jiang P, Park SY, Tamarina NA, Selleck SB, Wittkopp PJ, Bell GI, Kreitman M, Vilhjálmsson BJ. Effect of genetic variation in a Drosophila model of diabetes-associated misfolded human proinsulin. Genetics. 2014 Feb; 196(2):557-67. PMID: 24281155; PMCID: PMC3914626.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    31. Shalev SA, Tenenbaum-Rakover Y, Horovitz Y, Paz VP, Ye H, Carmody D, Highland HM, Boerwinkle E, Hanis CL, Muzny DM, Gibbs RA, Bell GI, Philipson LH, Greeley SA. Microcephaly, epilepsy, and neonatal diabetes due to compound heterozygous mutations in IER3IP1: insights into the natural history of a rare disorder. Pediatr Diabetes. 2014 May; 15(3):252-6. PMID: 24138066; PMCID: PMC3994177.
      Citations: 15     Fields:    Translation:Humans
    32. Naylor RN, John PM, Winn AN, Carmody D, Greeley SA, Philipson LH, Bell GI, Huang ES. Cost-effectiveness of MODY genetic testing: translating genomic advances into practical health applications. Diabetes Care. 2014; 37(1):202-9. PMID: 24026547; PMCID: PMC3867988.
      Citations: 51     Fields:    Translation:Humans
    33. Gillespie JR, Bush JR, Bell GI, Aubrey LA, Dupuis H, Ferron M, Kream B, DiMattia G, Patel S, Woodgett JR, Karsenty G, Hess DA, Beier F. GSK-3ß function in bone regulates skeletal development, whole-body metabolism, and male life span. Endocrinology. 2013 Oct; 154(10):3702-18. PMID: 23904355; PMCID: PMC5053811.
      Citations: 16     Fields:    Translation:AnimalsCells
    34. Yin H, Park SY, Wang XJ, Misawa R, Grossman EJ, Tao J, Zhong R, Witkowski P, Bell GI, Chong AS. Enhancing pancreatic Beta-cell regeneration in vivo with pioglitazone and alogliptin. PLoS One. 2013; 8(6):e65777. PMID: 23762423; PMCID: PMC3675063.
      Citations: 5     Fields:    Translation:AnimalsCells
    35. Ogata M, Awaji T, Iwasaki N, Fujimaki R, Takizawa M, Maruyama K, Bell GI, Iwamoto Y, Uchigata Y. Localization of hepatocyte nuclear factor-4a in the nucleolus and nucleus is regulated by its C-terminus. J Diabetes Investig. 2012 Oct 18; 3(5):449-56. PMID: 24843605; PMCID: PMC4019245.
      Citations: 3     Fields:    
    36. Savic D, Park SY, Bailey KA, Bell GI, Nobrega MA. In vitro scan for enhancers at the TCF7L2 locus. Diabetologia. 2013 Jan; 56(1):121-5. PMID: 23011354; PMCID: PMC3525810.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    37. Johansson S, Irgens H, Chudasama KK, Molnes J, Aerts J, Roque FS, Jonassen I, Levy S, Lima K, Knappskog PM, Bell GI, Molven A, Njølstad PR. Exome sequencing and genetic testing for MODY. PLoS One. 2012; 7(5):e38050. PMID: 22662265; PMCID: PMC3360646.
      Citations: 42     Fields:    Translation:Humans
    38. Savic D, Bell GI, Nobrega MA. An in vivo cis-regulatory screen at the type 2 diabetes associated TCF7L2 locus identifies multiple tissue-specific enhancers. PLoS One. 2012; 7(5):e36501. PMID: 22590553; PMCID: PMC3349716.
      Citations: 11     Fields:    Translation:AnimalsCells
    39. Chong AS, Bell GI. Three Strikes and You're Cured. Sci Transl Med. 2012 May 09; 4(133):133fs12. PMID: 22572878.
      Citations:    Fields:    Translation:HumansAnimals
    40. Bell GI, Putman DM, Hughes-Large JM, Hess DA. Intrapancreatic delivery of human umbilical cord blood aldehyde dehydrogenase-producing cells promotes islet regeneration. Diabetologia. 2012 Jun; 55(6):1755-60. PMID: 22434536.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    41. Greeley SA, Naylor RN, Philipson LH, Bell GI. Neonatal diabetes: an expanding list of genes allows for improved diagnosis and treatment. Curr Diab Rep. 2011 Dec; 11(6):519-32. PMID: 21993633; PMCID: PMC3226065.
      Citations: 48     Fields:    Translation:Humans
    42. Boodram LG, Miyake K, Hayes MG, Bell GI, Cockburn BN. Association of the KCNJ11 variant E23K with type 2 diabetes in Indo-Trinidadians. West Indian Med J. 2011 Dec; 60(6):604-7. PMID: 22512215.
      Citations: 2     Fields:    Translation:Humans
    43. Fajans SS, Bell GI. MODY: history, genetics, pathophysiology, and clinical decision making. Diabetes Care. 2011 Aug; 34(8):1878-84. PMID: 21788644; PMCID: PMC3142024.
      Citations: 117     Fields:    Translation:Humans
    44. Savic D, Ye H, Aneas I, Park SY, Bell GI, Nobrega MA. Alterations in TCF7L2 expression define its role as a key regulator of glucose metabolism. Genome Res. 2011 Sep; 21(9):1417-25. PMID: 21673050; PMCID: PMC3166827.
      Citations: 77     Fields:    Translation:HumansAnimalsCells
    45. Below JE, Gamazon ER, Morrison JV, Konkashbaev A, Pluzhnikov A, McKeigue PM, Parra EJ, Elbein SC, Hallman DM, Nicolae DL, Bell GI, Cruz M, Cox NJ, Hanis CL. Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals. Diabetologia. 2011 Aug; 54(8):2047-55. PMID: 21647700; PMCID: PMC3761075.
      Citations: 67     Fields:    Translation:Humans
    46. Naylor RN, Greeley SA, Bell GI, Philipson LH. Genetics and pathophysiology of neonatal diabetes mellitus. J Diabetes Investig. 2011 Jun 05; 2(3):158-69. PMID: 24843477; PMCID: PMC4014912.
      Citations: 30     Fields:    
    47. Lipton RB, Drum ML, Danielson KK, Greeley SA, Bell GI, Hagopian WA. Onset features and subsequent clinical evolution of childhood diabetes over several years. Pediatr Diabetes. 2011 Jun; 12(4 Pt 1):326-34. PMID: 21426455; PMCID: PMC3103597.
      Citations: 4     Fields:    Translation:HumansCells
    48. Lipton RB, Drum M, Greeley SA, Danielson KK, Bell GI, Hagopian WA. HLA-DQ haplotypes differ by ethnicity in patients with childhood-onset diabetes. Pediatr Diabetes. 2011 Jun; 12(4 Pt 2):388-95. PMID: 21418452; PMCID: PMC3406606.
      Citations: 7     Fields:    Translation:Humans
    49. Greeley SA, John PM, Winn AN, Ornelas J, Lipton RB, Philipson LH, Bell GI, Huang ES. The cost-effectiveness of personalized genetic medicine: the case of genetic testing in neonatal diabetes. Diabetes Care. 2011 Mar; 34(3):622-7. PMID: 21273495; PMCID: PMC3041194.
      Citations: 39     Fields:    Translation:Humans
    50. Fu YP, Hallman DM, Gonzalez VH, Klein BE, Klein R, Hayes MG, Cox NJ, Bell GI, Hanis CL. Identification of Diabetic Retinopathy Genes through a Genome-Wide Association Study among Mexican-Americans from Starr County, Texas. J Ophthalmol. 2010; 2010. PMID: 20871662; PMCID: PMC2939442.
      Citations: 52     
    51. Steiner DF, Park SY, Ye H, Philipson LH, Bell GI, Støy J. Clinical and molecular genetics of neonatal diabetes due to mutations in the insulin gene. Rev Endocr Metab Disord. 2010 Sep; 11(3):205-15. PMID: 20938745; PMCID: PMC2974937.
      Citations: 65     Fields:    Translation:HumansAnimalsCells
    52. Grossman E, Tao J, Wilson R, Park SY, Bell G, Chong A. Seeing is believing: how the MIP-luc mouse can advance the field of islet transplantation and ß-cell regeneration. Islets. 2010 Jul-Aug; 2(4):261-2. PMID: 21099322.
      Citations: 2     Fields:    Translation:AnimalsCells
    53. Cheverud JM, Fawcett GL, Jarvis JP, Norgard EA, Pavlicev M, Pletscher LS, Polonsky KS, Ye H, Bell GI, Semenkovich CF. Calpain-10 is a component of the obesity-related quantitative trait locus Adip1. J Lipid Res. 2010 May; 51(5):907-13. PMID: 20388922; PMCID: PMC2853458.
      Citations: 18     Fields:    Translation:Animals
    54. Greeley SA, Tucker SE, Naylor RN, Bell GI, Philipson LH. Neonatal diabetes mellitus: a model for personalized medicine. Trends Endocrinol Metab. 2010 Aug; 21(8):464-72. PMID: 20434356; PMCID: PMC2914172.
      Citations: 28     Fields:    Translation:HumansAnimals
    55. Fajans SS, Bell GI, Paz VP, Below JE, Cox NJ, Martin C, Thomas IH, Chen M. Obesity and hyperinsulinemia in a family with pancreatic agenesis and MODY caused by the IPF1 mutation Pro63fsX60. Transl Res. 2010 Jul; 156(1):7-14. PMID: 20621032; PMCID: PMC2904650.
      Citations: 18     Fields:    Translation:Humans
    56. Greeley SA, Tucker SE, Worrell HI, Skowron KB, Bell GI, Philipson LH. Update in neonatal diabetes. Curr Opin Endocrinol Diabetes Obes. 2010 Feb; 17(1):13-9. PMID: 19952737.
      Citations: 21     Fields:    Translation:HumansCells
    57. Grossman EJ, Lee DD, Tao J, Wilson RA, Park SY, Bell GI, Chong AS. Glycemic control promotes pancreatic beta-cell regeneration in streptozotocin-induced diabetic mice. PLoS One. 2010 Jan 18; 5(1):e8749. PMID: 20090914; PMCID: PMC2807460.
      Citations: 20     Fields:    Translation:Animals
    58. Park SY, Ye H, Steiner DF, Bell GI. Mutant proinsulin proteins associated with neonatal diabetes are retained in the endoplasmic reticulum and not efficiently secreted. Biochem Biophys Res Commun. 2010 Jan 15; 391(3):1449-54. PMID: 20034470; PMCID: PMC2817945.
      Citations: 59     Fields:    Translation:HumansAnimalsCells
    59. Rajan S, Eames SC, Park SY, Labno C, Bell GI, Prince VE, Philipson LH. In vitro processing and secretion of mutant insulin proteins that cause permanent neonatal diabetes. Am J Physiol Endocrinol Metab. 2010 Mar; 298(3):E403-10. PMID: 19952343; PMCID: PMC2838531.
      Citations: 52     Fields:    Translation:HumansAnimalsCells
    60. Villareal DT, Robertson H, Bell GI, Patterson BW, Tran H, Wice B, Polonsky KS. TCF7L2 variant rs7903146 affects the risk of type 2 diabetes by modulating incretin action. Diabetes. 2010 Feb; 59(2):479-85. PMID: 19934000; PMCID: PMC2809956.
      Citations: 67     Fields:    Translation:HumansCells
    61. Steiner DF, Park SY, Philipson LH, Bell GI, Støy J. A brief perspective on insulin production. Diabetes Obes Metab. 2009 Nov; 11 Suppl 4:189-96. PMID: 19817801.
      Citations: 45     Fields:    Translation:HumansCells
    62. Johnson JD, Otani K, Bell GI, Polonsky KS. Impaired insulin secretion in transgenic mice over-expressing calpastatin in pancreatic ß-cells. Islets. 2009 Nov-Dec; 1(3):242-8. PMID: 21099278; PMCID: PMC3044710.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    63. Kawai T, Ng MC, Hayes MG, Yoshiuchi I, Tsuchiya T, Robertson H, Cox NJ, Polonsky KS, Bell GI, Ehrmann DA. Variation in the perilipin gene (PLIN) affects glucose and lipid metabolism in non-Hispanic white women with and without polycystic ovary syndrome. Diabetes Res Clin Pract. 2009 Dec; 86(3):186-92. PMID: 19782423; PMCID: PMC2794304.
      Citations: 7     Fields:    Translation:Humans
    64. Bell G. The oligogenic view of adaptation. Cold Spring Harb Symp Quant Biol. 2009; 74:139-44. PMID: 19667015.
      Citations: 9     Fields:    Translation:Animals
    65. Villareal DT, Koster JC, Robertson H, Akrouh A, Miyake K, Bell GI, Patterson BW, Nichols CG, Polonsky KS. Kir6.2 variant E23K increases ATP-sensitive K+ channel activity and is associated with impaired insulin release and enhanced insulin sensitivity in adults with normal glucose tolerance. Diabetes. 2009 Aug; 58(8):1869-78. PMID: 19491206; PMCID: PMC2712777.
      Citations: 40     Fields:    Translation:Humans
    66. Park SY, Bell GI. Noninvasive monitoring of changes in pancreatic beta-cell mass by bioluminescent imaging in MIP-luc transgenic mice. Horm Metab Res. 2009 Jan; 41(1):1-4. PMID: 18949679; PMCID: PMC2610407.
      Citations: 11     Fields:    Translation:AnimalsCells
    67. Greeley SA, Paz VP, Ye H, Pastore AN, Skowron KB, Lipton RB, Cogen FR, Bell GI, Philipson LH, United States Neonatal Diabetes Working Group, Støy J. Diagnosis and treatment of neonatal diabetes: a United States experience. Pediatr Diabetes. 2008 Oct; 9(5):450-9. PMID: 18662362; PMCID: PMC2574846.
      Citations: 46     Fields:    Translation:Humans
    68. Molven A, Ringdal M, Raeder H, Lipkind GM, Steiner DF, Philipson LH, Bergmann I, Aarskog D, Undlien DE, Joner G, Norwegian Childhood Diabetes Study Group, Bell GI, Nordbø AM, Støy J, Søvik O, Njølstad PR. Mutations in the insulin gene can cause MODY and autoantibody-negative type 1 diabetes. Diabetes. 2008 Apr; 57(4):1131-5. PMID: 18192540.
      Citations: 87     Fields:    Translation:Humans
    69. Edghill EL, Flanagan SE, Patch AM, Boustred C, Parrish A, Shields B, Shepherd MH, Hussain K, Kapoor RR, Malecki M, MacDonald MJ, Steiner DF, Philipson LH, Bell GI, Neonatal Diabetes International Collaborative Group, Hattersley AT, Ellard S, Støy J. Insulin mutation screening in 1,044 patients with diabetes: mutations in the INS gene are a common cause of neonatal diabetes but a rare cause of diabetes diagnosed in childhood or adulthood. Diabetes. 2008 Apr; 57(4):1034-42. PMID: 18162506; PMCID: PMC7611804.
      Citations: 156     Fields:    Translation:Humans
    70. Norton L, Parr T, Chokkalingam K, Bardsley RG, Ye H, Bell GI, Pelsers MM, van Loon LJ, Tsintzas K. Calpain-10 gene and protein expression in human skeletal muscle: effect of acute lipid-induced insulin resistance and type 2 diabetes. J Clin Endocrinol Metab. 2008 Mar; 93(3):992-8. PMID: 18089694; PMCID: PMC2729205.
      Citations: 4     Fields:    Translation:Humans
    71. Hara M, Shen J, Pugh W, Polonsky KS, Le Beau MM, Bell GI. Sustained expression of hepatocyte nuclear factor-6 leads to loss of pancreatic beta-cells by apoptosis. Exp Clin Endocrinol Diabetes. 2007 Nov; 115(10):654-61. PMID: 18058600.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    72. Fajans SS, Bell GI. Macrosomia and neonatal hypoglycaemia in RW pedigree subjects with a mutation (Q268X) in the gene encoding hepatocyte nuclear factor 4alpha (HNF4A). Diabetologia. 2007 Dec; 50(12):2600-1. PMID: 17891372.
      Citations: 15     Fields:    Translation:Humans
    73. Edghill EL, Flanagan SE, Ye H, Paz VP, Pluzhnikov A, Below JE, Hayes MG, Cox NJ, Lipkind GM, Lipton RB, Greeley SA, Patch AM, Ellard S, Steiner DF, Hattersley AT, Philipson LH, Bell GI, Neonatal Diabetes International Collaborative Group, Støy J. Insulin gene mutations as a cause of permanent neonatal diabetes. Proc Natl Acad Sci U S A. 2007 Sep 18; 104(38):15040-4. PMID: 17855560; PMCID: PMC1986609.
      Citations: 245     Fields:    Translation:HumansCells
    74. Hayes MG, Pluzhnikov A, Miyake K, Sun Y, Ng MC, Roe CA, Below JE, Nicolae RI, Konkashbaev A, Bell GI, Cox NJ, Hanis CL. Identification of type 2 diabetes genes in Mexican Americans through genome-wide association studies. Diabetes. 2007 Dec; 56(12):3033-44. PMID: 17846124.
      Citations: 61     Fields:    Translation:Humans
    75. Tsuchiya T, Schwarz PE, Bosque-Plata LD, Geoffrey Hayes M, Dina C, Froguel P, Wayne Towers G, Fischer S, Temelkova-Kurktschiev T, Rietzsch H, Graessler J, Selisko T, Schulze J, Julius U, Hanefeld M, Weedon MN, Evans JC, Frayling TM, Hattersley AT, Orho-Melander M, Groop L, Malecki MT, Hansen T, Pedersen O, Fingerlin TE, Boehnke M, Hanis CL, Cox NJ, Bell GI, Vcelák J, Palyzová D, Bendlová B. Association of the calpain-10 gene with type 2 diabetes in Europeans: results of pooled and meta-analyses. Mol Genet Metab. 2006 Sep-Oct; 89(1-2):174-84. PMID: 16837224.
      Citations: 24     Fields:    Translation:Humans
    76. Odili S, Zelent D, Buettger C, Kwagh J, Stanley C, de Beaufort C, Bell GI, Han Y, Grimsby J, Taub R, Molven A, Matschinsky FM, Sagen JV, Bjørkhaug L, Dahl-Jørgensen K, Søvik O, Njølstad PR. From clinicogenetic studies of maturity-onset diabetes of the young to unraveling complex mechanisms of glucokinase regulation. Diabetes. 2006 Jun; 55(6):1713-22. PMID: 16731834.
      Citations: 43     Fields:    Translation:HumansCells
    77. Hathout E, Mace J, Bell GI, Njølstad PR. Treatment of hyperglycemia in a 7-year-old child diagnosed with neonatal diabetes. Diabetes Care. 2006 Jun; 29(6):1458. PMID: 16732049.
      Citations: 2     Fields:    Translation:Humans
    78. Salmenniemi U, Ruotsalainen E, Kuusisto J, Vauhkonen I, Kainulainen S, Ng MC, Cox NJ, Bell GI, Laakso M, Pihlajamäki J, Vänttinen M. Common polymorphisms of calpain-10 are associated with abdominal obesity in subjects at high risk of type 2 diabetes. Diabetologia. 2006 Jul; 49(7):1560-6. PMID: 16752174.
      Citations: 6     Fields:    Translation:Humans
    79. Odom DT, Dowell RD, Jacobsen ES, Nekludova L, Rolfe PA, Danford TW, Gifford DK, Fraenkel E, Bell GI, Young RA. Core transcriptional regulatory circuitry in human hepatocytes. Mol Syst Biol. 2006; 2:2006.0017. PMID: 16738562; PMCID: PMC1681491.
      Citations: 109     Fields:    Translation:HumansCells
    80. Fajans SS, Bell GI. Phenotypic heterogeneity between different mutations of MODY subtypes and within MODY pedigrees. Diabetologia. 2006 May; 49(5):1106-8. PMID: 16502298.
      Citations: 14     Fields:    Translation:Humans
    81. Hayes MG, del Bosque-Plata L, Tsuchiya T, Hanis CL, Bell GI, Cox NJ. Patterns of linkage disequilibrium in the type 2 diabetes gene calpain-10. Diabetes. 2005 Dec; 54(12):3573-6. PMID: 16306378.
      Citations: 3     Fields:    Translation:Humans
    82. Park SY, Wang X, Chen Z, Powers AC, Magnuson MA, Head WS, Piston DW, Bell GI. Optical imaging of pancreatic beta cells in living mice expressing a mouse insulin I promoter-firefly luciferase transgene. Genesis. 2005 Oct; 43(2):80-6. PMID: 16108006.
      Citations: 32     Fields:    Translation:AnimalsCells
    83. Ng MC, Miyake K, So WY, Poon EW, Lam VK, Li JK, Cox NJ, Bell GI, Chan JC. The linkage and association of the gene encoding upstream stimulatory factor 1 with type 2 diabetes and metabolic syndrome in the Chinese population. Diabetologia. 2005 Oct; 48(10):2018-24. PMID: 16132950.
      Citations: 23     Fields:    Translation:Humans
    84. Grasberger H, Bell GI. Subcellular recruitment by TSG118 and TSPYL implicates a role for zinc finger protein 106 in a novel developmental pathway. Int J Biochem Cell Biol. 2005 Jul; 37(7):1421-37. PMID: 15833274.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    85. Wang CZ, Wang Y, Di A, Magnuson MA, Ye H, Roe MW, Nelson DJ, Bell GI, Philipson LH. 5-amino-imidazole carboxamide riboside acutely potentiates glucose-stimulated insulin secretion from mouse pancreatic islets by KATP channel-dependent and -independent pathways. Biochem Biophys Res Commun. 2005 May 20; 330(4):1073-9. PMID: 15823553.
      Citations: 21     Fields:    Translation:AnimalsCells
    86. Cockburn BN, Bermano G, Boodram LL, Teelucksingh S, Tsuchiya T, Mahabir D, Allan AB, Stein R, Docherty K, Bell GI. Gene symbol: IPF1. Disease: MODY 4. Hum Genet. 2005 May; 116(6):538. PMID: 15991313.
      Citations: 3     Fields:    Translation:Humans
    87. Iwasaki N, Horikawa Y, Tsuchiya T, Kitamura Y, Nakamura T, Tanizawa Y, Oka Y, Hara K, Kadowaki T, Awata T, Honda M, Yamashita K, Oda N, Yu L, Yamada N, Ogata M, Kamatani N, Iwamoto Y, Del Bosque-Plata L, Hayes MG, Cox NJ, Bell GI. Genetic variants in the calpain-10 gene and the development of type 2 diabetes in the Japanese population. J Hum Genet. 2005; 50(2):92-98. PMID: 15696376.
      Citations: 4     Fields:    Translation:Humans
    88. Gunawardana SC, Hara M, Bell GI, Head WS, Magnuson MA, Piston DW. Imaging Beta cell development in real-time using pancreatic explants from mice with green fluorescent protein-labeled pancreatic Beta cells. In Vitro Cell Dev Biol Anim. 2005 Jan-Feb; 41(1-2):7-11. PMID: 15926862.
      Citations: 2     Fields:    Translation:Animals
    89. Grasberger H, Ye H, Mashima H, Bell GI. Dual promoter structure of ZFP106: regulation by myogenin and nuclear respiratory factor-1. Gene. 2005 Jan 03; 344:143-59. PMID: 15656981.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    90. Xie JT, Mehendale SR, Li X, Quigg R, Wang X, Wang CZ, Wu JA, Aung HH, A Rue P, Bell GI, Yuan CS. Anti-diabetic effect of ginsenoside Re in ob/ob mice. Biochim Biophys Acta. 2005 Jun 10; 1740(3):319-25. PMID: 15949698.
      Citations: 54     Fields:    Translation:Animals
    91. Ng MC, So WY, Lam VK, Cockram CS, Bell GI, Cox NJ, Chan JC. Genome-wide scan for metabolic syndrome and related quantitative traits in Hong Kong Chinese and confirmation of a susceptibility locus on chromosome 1q21-q25. Diabetes. 2004 Oct; 53(10):2676-83. PMID: 15448100.
      Citations: 41     Fields:    Translation:HumansCells
    92. Raeder H, Hathout E, Shehadeh N, Gudmundsson K, Baevre H, Abuelo D, Phornphutkul C, Molnes J, Bell GI, Gloyn AL, Hattersley AT, Molven A, Sagen JV, Søvik O, Njølstad PR. Permanent neonatal diabetes due to mutations in KCNJ11 encoding Kir6.2: patient characteristics and initial response to sulfonylurea therapy. Diabetes. 2004 Oct; 53(10):2713-8. PMID: 15448106.
      Citations: 116     Fields:    Translation:Humans
    93. Bell G, Dickson U, Arana A, Robinson D, Marshall C, Morton N. Remifentanil vs fentanyl/morphine for pain and stress control during pediatric cardiac surgery. Paediatr Anaesth. 2004 Oct; 14(10):856-60. PMID: 15385015.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    94. Moran NF, Poole K, Bell G, Solomon J, Kendall S, McCarthy M, McCormick D, Nashef L, Sander J, Shorvon SD. Epilepsy in the United Kingdom: seizure frequency and severity, anti-epileptic drug utilization and impact on life in 1652 people with epilepsy. Seizure. 2004 Sep; 13(6):425-33. PMID: 15276147.
      Citations: 33     Fields:    Translation:Humans
    95. Alcoser SY, Hara M, Bell GI, Ehrmann DA. Association of the (AU)AT-rich element polymorphism in PPP1R3 with hormonal and metabolic features of polycystic ovary syndrome. J Clin Endocrinol Metab. 2004 Jun; 89(6):2973-6. PMID: 15181086.
      Citations: 1     Fields:    Translation:HumansCells
    96. Ng MC, So WY, Cox NJ, Lam VK, Cockram CS, Critchley JA, Bell GI, Chan JC. Genome-wide scan for type 2 diabetes loci in Hong Kong Chinese and confirmation of a susceptibility locus on chromosome 1q21-q25. Diabetes. 2004 Jun; 53(6):1609-13. PMID: 15161769.
      Citations: 26     Fields:    Translation:HumansCells
    97. Johnson JD, Han Z, Otani K, Ye H, Zhang Y, Wu H, Horikawa Y, Misler S, Bell GI, Polonsky KS. RyR2 and calpain-10 delineate a novel apoptosis pathway in pancreatic islets. J Biol Chem. 2004 Jun 04; 279(23):24794-802. PMID: 15044459.
      Citations: 50     Fields:    Translation:HumansAnimalsCells
    98. Otani K, Han DH, Ford EL, Garcia-Roves PM, Ye H, Horikawa Y, Bell GI, Holloszy JO, Polonsky KS. Calpain system regulates muscle mass and glucose transporter GLUT4 turnover. J Biol Chem. 2004 May 14; 279(20):20915-20. PMID: 15014085.
      Citations: 19     Fields:    Translation:HumansAnimals
    99. Odom DT, Zizlsperger N, Gordon DB, Bell GW, Rinaldi NJ, Murray HL, Volkert TL, Rolfe PA, Gifford DK, Fraenkel E, Bell GI, Young RA, Schreiber J. Control of pancreas and liver gene expression by HNF transcription factors. Science. 2004 Feb 27; 303(5662):1378-81. PMID: 14988562; PMCID: PMC3012624.
      Citations: 561     Fields:    Translation:HumansCells
    100. del Bosque-Plata L, Aguilar-Salinas CA, Hanis CL, Tsuchiya T, Yoshiuchi I, Cox NJ, Bell GI, Tusié-Luna MT, Ramírez-Jiménez S, Rodríguez-Torres M, Aurón-Gómez M, Ramírez E, Velasco-Pérez ML, Ramírez-Silva A, Gómez-Pérez F. Association of the calpain-10 gene with type 2 diabetes mellitus in a Mexican population. Mol Genet Metab. 2004 Feb; 81(2):122-6. PMID: 14741193.
      Citations: 13     Fields:    Translation:Humans
    101. Cox NJ, Hayes MG, Roe CA, Tsuchiya T, Bell GI. Linkage of calpain 10 to type 2 diabetes: the biological rationale. Diabetes. 2004 Feb; 53 Suppl 1:S19-25. PMID: 14749261.
      Citations: 16     Fields:    Translation:Humans
    102. Cockburn BN, Bermano G, Boodram LL, Teelucksingh S, Tsuchiya T, Mahabir D, Allan AB, Stein R, Docherty K, Bell GI. Insulin promoter factor-1 mutations and diabetes in Trinidad: identification of a novel diabetes-associated mutation (E224K) in an Indo-Trinidadian family. J Clin Endocrinol Metab. 2004 Feb; 89(2):971-8. PMID: 14764823.
      Citations: 17     Fields:    Translation:HumansCells
    103. Martin IM, Ghani A, Bell G, Kinghorn G, Ison CA. Persistence of two genotypes of Neisseria gonorrhoeae during transmission. J Clin Microbiol. 2003 Dec; 41(12):5609-14. PMID: 14662949; PMCID: PMC308993.
      Citations: 7     Fields:    Translation:HumansCells
    104. Weedon MN, Schwarz PE, Horikawa Y, Iwasaki N, Illig T, Holle R, Rathmann W, Selisko T, Schulze J, Owen KR, Evans J, Del Bosque-Plata L, Hitman G, Walker M, Levy JC, Sampson M, Bell GI, McCarthy MI, Hattersley AT, Frayling TM. Meta-analysis and a large association study confirm a role for calpain-10 variation in type 2 diabetes susceptibility. Am J Hum Genet. 2003 Nov; 73(5):1208-12. PMID: 14574648; PMCID: PMC1180500.
      Citations: 45     Fields:    Translation:Humans
    105. So WY, Ng MC, Horikawa Y, Li JK, Ma RC, Bell GI, Chan JC, Njølstad PR. Genetic variants of hepatocyte nuclear factor-1beta in Chinese young-onset diabetic patients with nephropathy. J Diabetes Complications. 2003 Nov-Dec; 17(6):369-73. PMID: 14583183.
      Citations: 1     Fields:    Translation:Humans
    106. Naoumova RP, Bonney SA, Eichenbaum-Voline S, Patel HN, Jones B, Jones EL, Amey J, Colilla S, Neuwirth CK, Allotey R, Seed M, Betteridge DJ, Galton DJ, Cox NJ, Bell GI, Scott J, Shoulders CC. Confirmed locus on chromosome 11p and candidate loci on 6q and 8p for the triglyceride and cholesterol traits of combined hyperlipidemia. Arterioscler Thromb Vasc Biol. 2003 Nov 01; 23(11):2070-7. PMID: 14500288.
      Citations: 10     Fields:    Translation:HumansCells
    107. Zhou YP, Sreenan S, Pan CY, Currie KP, Bindokas VP, Horikawa Y, Lee JP, Ostrega D, Ahmed N, Baldwin AC, Cox NJ, Fox AP, Miller RJ, Bell GI, Polonsky KS. A 48-hour exposure of pancreatic islets to calpain inhibitors impairs mitochondrial fuel metabolism and the exocytosis of insulin. Metabolism. 2003 May; 52(5):528-34. PMID: 12759879.
      Citations: 16     Fields:    Translation:AnimalsCells
    108. Polonsky KS, Bell GI. Organ alchemy: producing insulin in the liver. Nat Med. 2003 May; 9(5):504-5. PMID: 12724755.
      Citations:    Fields:    Translation:AnimalsCells
    109. Aguilar-Salinas CA, Riba L, Zentella-Dehesa A, Rull J, Cox NJ, Bell GI, Canizales-Quinteros S, Reyes-Rodríguez E, Rodríguez-Torres M, Ramírez-Jiménez S, Huertas-Vázquez A, Fragoso-Ontiveros V, Ventura-Gallegos JL, Vega-Hernández G, López-Estrada A, Aurón-Gómez M, Gómez-Pérez F, Tusié-Luna MT. Locus on chromosome 6p linked to elevated HDL cholesterol serum levels and to protection against premature atherosclerosis in a kindred with familial hypercholesterolemia. Circ Res. 2003 Mar 21; 92(5):569-76. PMID: 12609970.
      Citations: 8     Fields:    Translation:HumansCells
    110. Iwasaki N, Cox NJ, Wang YQ, Schwarz PE, Bell GI, Honda M, Imura M, Ogata M, Saito M, Kamatani N, Iwamoto Y. Mapping genes influencing type 2 diabetes risk and BMI in Japanese subjects. Diabetes. 2003 Jan; 52(1):209-13. PMID: 12502515.
      Citations: 22     Fields:    Translation:Humans
    111. Berglund L, Jensen JN, Hansen L, Borch-Johnsen K, Horikawa Y, Mashima H, Lithell H, Cox NJ, Hansen T, Bell GI, Pedersen O, Berglund L, Jensen JN, Hansen L, Borch-Johnsen K, Horikawa Y, Mashima H, Lithell H, Cox NJ, Hansen T, Bell GI, Pedersen O. Variants within the calpain-10 gene on chromosome 2q37 (NIDDM1) and relationships to type 2 diabetes, insulin resistance, and impaired acute insulin secretion among Scandinavian Caucasians. Diabetes. 2002 Dec; 51(12):3561-7. PMID: 12453914.
      Citations: 22     Fields:    Translation:HumansCells
    112. Hara M, Wang X, Kawamura T, Bindokas VP, Dizon RF, Alcoser SY, Magnuson MA, Bell GI, Hara M, Wang X, Kawamura T, Bindokas VP, Dizon RF, Alcoser SY, Magnuson MA, Bell GI. Transgenic mice with green fluorescent protein-labeled pancreatic beta -cells. Am J Physiol Endocrinol Metab. 2003 Jan; 284(1):E177-83. PMID: 12388130.
      Citations: 177     Fields:    Translation:AnimalsCells
    113. Ehrmann DA, Tang X, Yoshiuchi I, Cox NJ, Bell GI. Relationship of insulin receptor substrate-1 and -2 genotypes to phenotypic features of polycystic ovary syndrome. J Clin Endocrinol Metab. 2002 Sep; 87(9):4297-300. PMID: 12213887.
      Citations: 19     Fields:    Translation:HumansCells
    114. Haddad L, Evans JC, Gharani N, Robertson C, Rush K, Wiltshire S, Frayling TM, Wilkin TJ, Demaine A, Millward A, Hattersley AT, Conway G, Cox NJ, Bell GI, Franks S, McCarthy MI, Haddad L, Evans JC, Gharani N, Robertson C, Rush K, Wiltshire S, Frayling TM, Wilkin TJ, Demaine A, Millward A, Hattersley AT, Conway G, Cox NJ, Bell GI, Franks S, McCarthy MI. Variation within the type 2 diabetes susceptibility gene calpain-10 and polycystic ovary syndrome. J Clin Endocrinol Metab. 2002 Jun; 87(6):2606-10. PMID: 12050223.
      Citations: 14     Fields:    Translation:Humans
    115. Ehrmann DA, Schwarz PE, Hara M, Tang X, Horikawa Y, Imperial J, Bell GI, Cox NJ. Relationship of calpain-10 genotype to phenotypic features of polycystic ovary syndrome. J Clin Endocrinol Metab. 2002 Apr; 87(4):1669-73. PMID: 11932299.
      Citations: 19     Fields:    Translation:Humans
    116. Joost HG, Bell GI, Best JD, Birnbaum MJ, Charron MJ, Chen YT, Doege H, James DE, Lodish HF, Moley KH, Moley JF, Mueckler M, Rogers S, Seino S, Thorens B, Schürmann A. Nomenclature of the GLUT/SLC2A family of sugar/polyol transport facilitators. Am J Physiol Endocrinol Metab. 2002 Apr; 282(4):E974-6. PMID: 11882521.
      Citations: 119     Fields:    
    117. Ogata M, Awaji T, Iwasaki N, Miyazaki S, Bell GI, Iwamoto Y. Nuclear translocation of SHP and visualization of interaction with HNF-4alpha in living cells. Biochem Biophys Res Commun. 2002 Mar 22; 292(1):8-12. PMID: 11890664.
      Citations: 5     Fields:    Translation:AnimalsCells
    118. Fullerton SM, Bartoszewicz A, Ybazeta G, Horikawa Y, Bell GI, Kidd KK, Cox NJ, Hudson RR, Di Rienzo A. Geographic and haplotype structure of candidate type 2 diabetes susceptibility variants at the calpain-10 locus. Am J Hum Genet. 2002 May; 70(5):1096-106. PMID: 11891618; PMCID: PMC447588.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    119. Jeon JY, Weiss CB, Steadward RD, Ryan E, Burnham RS, Bell G, Chilibeck P, Wheeler GD. Improved glucose tolerance and insulin sensitivity after electrical stimulation-assisted cycling in people with spinal cord injury. Spinal Cord. 2002 Mar; 40(3):110-7. PMID: 11859437.
      Citations: 30     Fields:    Translation:Humans
    120. Forsythe SM, Kogut PC, McConville JF, Fu Y, McCauley JA, Halayko AJ, Liu HW, Kao A, Fernandes DJ, Bellam S, Fuchs E, Sinha S, Bell GI, Camoretti-Mercado B, Solway J. Structure and transcription of the human m3 muscarinic receptor gene. Am J Respir Cell Mol Biol. 2002 Mar; 26(3):298-305. PMID: 11867338.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    121. Lynn S, Evans JC, White C, Frayling TM, Hattersley AT, Turnbull DM, Horikawa Y, Cox NJ, Bell GI, Walker M. Variation in the calpain-10 gene affects blood glucose levels in the British population. Diabetes. 2002 Jan; 51(1):247-50. PMID: 11756349.
      Citations: 19     Fields:    Translation:Humans
    122. Bell GI, Polonsky KS. Diabetes mellitus and genetically programmed defects in beta-cell function. Nature. 2001 Dec 13; 414(6865):788-91. PMID: 11742410.
      Citations: 161     Fields:    Translation:HumansAnimals
    123. Fajans SS, Bell GI, Polonsky KS, Fajans SS, Bell GI, Polonsky KS. Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young. N Engl J Med. 2001 Sep 27; 345(13):971-80. PMID: 11575290.
      Citations: 276     Fields:    Translation:Humans
    124. Sreenan SK, Zhou YP, Otani K, Hansen PA, Currie KP, Pan CY, Lee JP, Ostrega DM, Pugh W, Horikawa Y, Cox NJ, Hanis CL, Burant CF, Fox AP, Bell GI, Polonsky KS, Sreenan SK, Zhou YP, Otani K, Hansen PA, Currie KP, Pan CY, Lee JP, Ostrega DM, Pugh W, Horikawa Y, Cox NJ, Hanis CL, Burant CF, Fox AP, Bell GI, Polonsky KS. Calpains play a role in insulin secretion and action. Diabetes. 2001 Sep; 50(9):2013-20. PMID: 11522666.
      Citations: 45     Fields:    Translation:AnimalsCells
    125. Evans JC, Frayling TM, Cassell PG, Saker PJ, Hitman GA, Walker M, Levy JC, O'Rahilly S, Rao PV, Bennett AJ, Jones EC, Menzel S, Prestwich P, Simecek N, Wishart M, Dhillon R, Fletcher C, Millward A, Demaine A, Wilkin T, Horikawa Y, Cox NJ, Bell GI, Ellard S, McCarthy MI, Hattersley AT, Evans JC, Frayling TM, Cassell PG, Saker PJ, Hitman GA, Walker M, Levy JC, O'Rahilly S, Rao PV, Bennett AJ, Jones EC, Menzel S, Prestwich P, Simecek N, Wishart M, Dhillon R, Fletcher C, Millward A, Demaine A, Wilkin T, Horikawa Y, Cox NJ, Bell GI, Ellard S, McCarthy MI, Hattersley AT. Studies of association between the gene for calpain-10 and type 2 diabetes mellitus in the United Kingdom. Am J Hum Genet. 2001 Sep; 69(3):544-52. PMID: 11481585; PMCID: PMC1235484.
      Citations: 38     Fields:    Translation:Humans
    126. Massa O, Barbetti F, Undlien DE, Shiota C, Magnuson MA, Molven A, Matschinsky FM, Bell GI, Njølstad PR, Søvik O, Cuesta-Muñoz A, Bjørkhaug L. Neonatal diabetes mellitus due to complete glucokinase deficiency. N Engl J Med. 2001 May 24; 344(21):1588-92. PMID: 11372010.
      Citations: 113     Fields:    Translation:Humans
    127. Yang X, Pratley RE, Baier LJ, Horikawa Y, Bell GI, Bogardus C, Permana PA. Reduced skeletal muscle calpain-10 transcript level is due to a cumulative decrease in major isoforms. Mol Genet Metab. 2001 May; 73(1):111-3. PMID: 11350192.
      Citations: 7     Fields:    Translation:HumansCells
    128. del Bosque-Plata L, Lin J, Horikawa Y, Schwarz PE, Cox NJ, Iwasaki N, Ogata M, Iwamoto Y, German MS, Bell GI. Mutations in the coding region of the neurogenin 3 gene (NEUROG3) are not a common cause of maturity-onset diabetes of the young in Japanese subjects. Diabetes. 2001 Mar; 50(3):694-6. PMID: 11246894.
      Citations: 6     Fields:    Translation:HumansCells
    129. Hara M, Wang X, Paz VP, Iwasaki N, Honda M, Iwamoto Y, Bell GI. Identification of three missense mutations in the peroxisome proliferator-activated receptor alpha gene in Japanese subjects with maturity-onset diabetes of the young. J Hum Genet. 2001; 46(5):285-8. PMID: 11355020.
      Citations: 3     Fields:    Translation:Humans
    130. Moore GE, Abu-Amero SN, Bell G, Wakeling EL, Kingsnorth A, Stanier P, Jauniaux E, Bennett ST. Evidence that insulin is imprinted in the human yolk sac. Diabetes. 2001 Jan; 50(1):199-203. PMID: 11147788.
      Citations: 25     Fields:    Translation:Humans
    131. Poole K, Moran N, Bell G, Solomon J, Kendall S, McCarthy M, McCormick D, Nashef L, Johnson A, Sander J, Shorvon S. Patients' perspectives on services for epilepsy: a survey of patient satisfaction, preferences and information provision in 2394 people with epilepsy. Seizure. 2000 Dec; 9(8):551-8. PMID: 11162752.
      Citations: 13     Fields:    Translation:Humans
    132. Moran N, Poole K, Bell G, Solomon J, Kendall S, McCarthy M, McCormick D, Nashef L, Johnson A, Sander J, Shorvon S. NHS services for epilepsy from the patient's perspective: a survey of primary, secondary and tertiary care access throughout the UK. Seizure. 2000 Dec; 9(8):559-65. PMID: 11162753.
      Citations: 3     Fields:    Translation:Humans
    133. Buckling A, Kassen R, Bell G, Rainey PB. Disturbance and diversity in experimental microcosms. Nature. 2000 Dec 21-28; 408(6815):961-4. PMID: 11140680.
      Citations: 60     Fields:    Translation:Cells
    134. Ward H, Ison CA, Day SE, Martin I, Ghani AC, Garnett GP, Bell G, Kinghorn G, Weber JN. A prospective social and molecular investigation of gonococcal transmission. Lancet. 2000 Nov 25; 356(9244):1812-7. PMID: 11117914.
      Citations: 14     Fields:    Translation:HumansCellsPHPublic Health
    135. Horikawa Y, Horikawa Y, Cox NJ, Iwasaki N, Ogata M, Iwamoto Y, Schwitzgebel V, German MS, Bell GI. beta-cell transcription factors and diabetes: no evidence for diabetes-associated mutations in the gene encoding the basic helix-loop-helix transcription factor neurogenic differentiation 4 (NEUROD4) in Japanese patients with MODY. Diabetes. 2000 Nov; 49(11):1955-7. PMID: 11078465.
      Citations: 1     Fields:    Translation:HumansCells
    136. Horikawa Y, Oda N, Cox NJ, Li X, Orho-Melander M, Hara M, Hinokio Y, Lindner TH, Mashima H, Schwarz PE, del Bosque-Plata L, Horikawa Y, Oda Y, Yoshiuchi I, Colilla S, Polonsky KS, Wei S, Concannon P, Iwasaki N, Schulze J, Baier LJ, Bogardus C, Groop L, Boerwinkle E, Hanis CL, Bell GI. Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus. Nat Genet. 2000 Oct; 26(2):163-75. PMID: 11017071.
      Citations: 316     Fields:    Translation:HumansCells
    137. Baier LJ, Permana PA, Yang X, Pratley RE, Hanson RL, Shen GQ, Mott D, Knowler WC, Cox NJ, Horikawa Y, Oda N, Bell GI, Bogardus C. A calpain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance. J Clin Invest. 2000 Oct; 106(7):R69-73. PMID: 11018080; PMCID: PMC387246.
      Citations: 67     Fields:    Translation:Humans
    138. Eeckhoute J, Suaud L, Briche I, Furuta H, Bell GI, Formstecher P, Laine B. Functional properties of the R154X HNF-4alpha protein generated by a mutation associated with maturity-onset diabetes of the young, type 1. FEBS Lett. 2000 Aug 11; 479(1-2):41-5. PMID: 10940385.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    139. Kassen R, Buckling A, Bell G, Rainey PB. Diversity peaks at intermediate productivity in a laboratory microcosm. Nature. 2000 Aug 03; 406(6795):508-12. PMID: 10952310.
      Citations: 62     Fields:    Translation:Cells
    140. Hara M, Wang X, Paz VP, Cox NJ, Iwasaki N, Ogata M, Iwamoto Y, Bell GI. No diabetes-associated mutations in the coding region of the hepatocyte nuclear factor-4gamma gene (HNF4G) in Japanese patients with MODY. Diabetologia. 2000 Aug; 43(8):1064-9. PMID: 10990086.
      Citations: 2     Fields:    Translation:HumansCells
    141. Ng MC, Li JK, So WY, Critchley JA, Cockram CS, Bell GI, Chan JC. Nature or nurture: an insightful illustration from a Chinese family with hepatocyte nuclear factor-1 alpha diabetes (MODY3) Diabetologia. 2000 Jun; 43(6):816-8. PMID: 10907130.
      Citations: 4     Fields:    Translation:Humans
    142. Bell GI, Molven A, Bjørkhaug L, Søvik O, Njølstad PR. A simple test for the high-frequency P291fsinsC mutation in the HNF1 alpha/MODY3 gene. Diabetologia. 2000 Jun; 43(6):818-9. PMID: 10907131.
      Citations: 1     Fields:    Translation:HumansCells
    143. Ilag LL, Tabaei BP, Herman WH, Zawacki CM, D'Souza E, Bell GI, Fajans SS. Reduced pancreatic polypeptide response to hypoglycemia and amylin response to arginine in subjects with a mutation in the HNF-4alpha/MODY1 gene. Diabetes. 2000 Jun; 49(6):961-8. PMID: 10866048.
      Citations: 3     Fields:    Translation:Humans
    144. Johnson P, Duncan K, Blunt S, Bell G, Ali Z, Cox P, Moore GE. Apparent confined placental mosaicism of trisomy 16 and multiple fetal anomalies: case report. Prenat Diagn. 2000 May; 20(5):417-21. PMID: 10820412.
      Citations: 3     Fields:    Translation:HumansCells
    145. Bell G, Ménoret A. Purification of multiple heat shock proteins from a single tumor sample. J Immunol Methods. 2000 Apr 03; 237(1-2):119-30. PMID: 10725457.
      Citations: 7     Fields:    Translation:Animals
    146. Moore GE, Ruangvutilert P, Chatzimeletiou K, Bell G, Chen CK, Johnson P, Harper JC. Examination of trisomy 13, 18 and 21 foetal tissues at different gestational ages using FISH. Eur J Hum Genet. 2000 Mar; 8(3):223-8. PMID: 10780789.
      Citations:    Fields:    Translation:HumansCells
    147. Bingham C, Ellard S, Allen L, Bulman M, Shepherd M, Frayling T, Berry PJ, Clark PM, Lindner T, Bell GI, Ryffel GU, Nicholls AJ, Hattersley AT. Abnormal nephron development associated with a frameshift mutation in the transcription factor hepatocyte nuclear factor-1 beta. Kidney Int. 2000 Mar; 57(3):898-907. PMID: 10720943.
      Citations: 41     Fields:    Translation:HumansCells
    148. Hinokio Y, Horikawa Y, Furuta H, Cox NJ, Iwasaki N, Honda M, Ogata M, Iwamoto Y, Bell GI. Beta-cell transcription factors and diabetes: no evidence for diabetes-associated mutations in the hepatocyte nuclear factor-3beta gene (HNF3B) in Japanese patients with maturity-onset diabetes of the young. Diabetes. 2000 Feb; 49(2):302-5. PMID: 10868948.
      Citations: 1     Fields:    Translation:Humans
    149. Kong A, Frigge M, Bell GI, Lander ES, Daly MJ, Cox NJ. Diabetes, dependence, asymptotics, selection and significance. Nat Genet. 1997 Oct; 17(2):148. PMID: 9326932.
      Citations: 3     Fields:    Translation:Humans
    150. Lindner T, Gragnoli C, Furuta H, Cockburn BN, Petzold C, Rietzsch H, Weiss U, Schulze J, Bell GI. Hepatic function in a family with a nonsense mutation (R154X) in the hepatocyte nuclear factor-4alpha/MODY1 gene. J Clin Invest. 1997 Sep 15; 100(6):1400-5. PMID: 9294105; PMCID: PMC508318.
      Citations: 18     Fields:    Translation:HumansCells
    151. Cockburn BN, Ostrega DM, Sturis J, Kubstrup C, Polonsky KS, Bell GI. Changes in pancreatic islet glucokinase and hexokinase activities with increasing age, obesity, and the onset of diabetes. Diabetes. 1997 Sep; 46(9):1434-9. PMID: 9287043.
      Citations: 12     Fields:    Translation:AnimalsCells
    152. Chien EK, Tokuyama Y, Rouard M, Phillippe M, Bell GI. Identification of gestationally regulated genes in rat myometrium by use of messenger ribonucleic acid differential display. Am J Obstet Gynecol. 1997 Sep; 177(3):645-52. PMID: 9322637.
      Citations: 3     Fields:    Translation:AnimalsCells
    153. Iwasaki N, Oda N, Ogata M, Hara M, Hinokio Y, Oda Y, Yamagata K, Kanematsu S, Ohgawara H, Omori Y, Bell GI. Mutations in the hepatocyte nuclear factor-1alpha/MODY3 gene in Japanese subjects with early- and late-onset NIDDM. Diabetes. 1997 Sep; 46(9):1504-8. PMID: 9287053.
      Citations: 13     Fields:    Translation:Humans
    154. Chien EK, Hara M, Rouard M, Yano H, Phillippe M, Polonsky KS, Bell GI. Increase in serum leptin and uterine leptin receptor messenger RNA levels during pregnancy in rats. Biochem Biophys Res Commun. 1997 Aug 18; 237(2):476-80. PMID: 9268737.
      Citations: 7     Fields:    Translation:Animals
    155. Zeyl C, Bell G. The advantage of sex in evolving yeast populations. Nature. 1997 Jul 31; 388(6641):465-8. PMID: 9242403.
      Citations: 42     Fields:    Translation:Animals
    156. Ren J, Bell G, Coy DH, Brunicardi FC. Activation of human somatostatin receptor type 2 causes inhibition of cell growth in transfected HEK293 but not in transfected CHO cells. J Surg Res. 1997 Jul 15; 71(1):13-8. PMID: 9271272.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    157. Lindner T, Gragnoli C, Schulze J, Rietzsch H, Petzold C, Cox NJ, Bell GI, Schröder HE. The 31-cM region of chromosome 11 including the obesity gene tubby and ATP-sensitive potassium channel genes, SUR1 and Kir6.2, does not contain a major susceptibility locus for NIDDM in 127 non-Hispanic white affected sibships. Diabetes. 1997 Jul; 46(7):1227-9. PMID: 9200660.
      Citations: 2     Fields:    Translation:HumansCells
    158. Hromas R, Gray PW, Chantry D, Godiska R, Krathwohl M, Fife K, Bell GI, Takeda J, Aronica S, Gordon M, Cooper S, Broxmeyer HE, Klemsz MJ. Cloning and characterization of exodus, a novel beta-chemokine. Blood. 1997 May 01; 89(9):3315-22. PMID: 9129037.
      Citations: 47     Fields:    Translation:HumansCells
    159. Hansen T, Eiberg H, Rouard M, Vaxillaire M, Rasmussen SK, Fridberg M, Urhammer SA, Holst JJ, Almind K, Echwald SM, Hansen L, Bell GI, Pedersen O, Møller AM. Novel MODY3 mutations in the hepatocyte nuclear factor-1alpha gene: evidence for a hyperexcitability of pancreatic beta-cells to intravenous secretagogues in a glucose-tolerant carrier of a P447L mutation. Diabetes. 1997 Apr; 46(4):726-30. PMID: 9075819.
      Citations: 20     Fields:    Translation:Humans
    160. Vaxillaire M, Rouard M, Yamagata K, Oda N, Kaisaki PJ, Boriraj VV, Chevre JC, Boccio V, Cox RD, Lathrop GM, Dussoix P, Philippe J, Timsit J, Charpentier G, Velho G, Bell GI, Froguel P. Identification of nine novel mutations in the hepatocyte nuclear factor 1 alpha gene associated with maturity-onset diabetes of the young (MODY3). Hum Mol Genet. 1997 Apr; 6(4):583-6. PMID: 9097962.
      Citations: 26     Fields:    Translation:Humans
    161. Urhammer SA, Rasmussen SK, Kaisaki PJ, Oda N, Yamagata K, Fridberg M, Hansen L, Hansen T, Bell GI, Pedersen O, Møller AM. Genetic variation in the hepatocyte nuclear factor-1 alpha gene in Danish Caucasians with late-onset NIDDM. Diabetologia. 1997 Apr; 40(4):473-5. PMID: 9112026.
      Citations: 6     Fields:    Translation:HumansCells
    162. Bell GI, Jurka J. The length distribution of perfect dimer repetitive DNA is consistent with its evolution by an unbiased single-step mutation process. J Mol Evol. 1997 Apr; 44(4):414-21. PMID: 9089081.
      Citations: 22     Fields:    Translation:AnimalsCells
    163. Frayling TM, Bulamn MP, Ellard S, Appleton M, Dronsfield MJ, Mackie AD, Baird JD, Kaisaki PJ, Yamagata K, Bell GI, Bain SC, Hattersley AT. Mutations in the hepatocyte nuclear factor-1alpha gene are a common cause of maturity-onset diabetes of the young in the U.K. Diabetes. 1997 Apr; 46(4):720-5. PMID: 9075818.
      Citations: 29     Fields:    Translation:Humans
    164. Kaisaki PJ, Menzel S, Lindner T, Oda N, Rjasanowski I, Sahm J, Meincke G, Schulze J, Schmechel H, Petzold C, Ledermann HM, Sachse G, Boriraj VV, Menzel R, Kerner W, Turner RC, Yamagata K, Bell GI. Mutations in the hepatocyte nuclear factor-1alpha gene in MODY and early-onset NIDDM: evidence for a mutational hotspot in exon 4. Diabetes. 1997 Mar; 46(3):528-35. PMID: 9032114.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    165. Burnham R, Martin T, Stein R, Bell G, MacLean I, Steadward R. Skeletal muscle fibre type transformation following spinal cord injury. Spinal Cord. 1997 Feb; 35(2):86-91. PMID: 9044514.
      Citations: 61     Fields:    Translation:HumansCellsCTClinical Trials
    166. Vaxillaire M, Pardini VC, Timsit J, Passa P, Deschamps I, Robert JJ, Weber IT, Marotta D, Pilkis SJ, Lipkind GM, Bell GI, Froguel P, Velho G, Blanché H, Bellanné-Chantelot C. Identification of 14 new glucokinase mutations and description of the clinical profile of 42 MODY-2 families. Diabetologia. 1997 Feb; 40(2):217-24. PMID: 9049484.
      Citations: 58     Fields:    Translation:Humans
    167. Yamagata K, Oda N, Kaisaki PJ, Menzel S, Furuta H, Vaxillaire M, Southam L, Cox RD, Lathrop GM, Boriraj VV, Chen X, Cox NJ, Oda Y, Yano H, Le Beau MM, Yamada S, Nishigori H, Takeda J, Fajans SS, Hattersley AT, Iwasaki N, Hansen T, Pedersen O, Polonsky KS, Bell GI, et al. Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3) Nature. 1996 Dec 05; 384(6608):455-8. PMID: 8945470.
      Citations: 295     Fields:    Translation:HumansAnimalsCells
    168. Yamagata K, Furuta H, Oda N, Kaisaki PJ, Menzel S, Cox NJ, Fajans SS, Signorini S, Stoffel M, Bell GI. Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young (MODY1) Nature. 1996 Dec 05; 384(6608):458-60. PMID: 8945471.
      Citations: 329     Fields:    Translation:Humans
    169. Semina EV, Datson NA, Leysens NJ, Zabel BU, Carey JC, Bell GI, Bitoun P, Lindgren C, Stevenson T, Frants RR, van Ommen G, Murray JC. Exclusion of epidermal growth factor and high-resolution physical mapping across the Rieger syndrome locus. Am J Hum Genet. 1996 Dec; 59(6):1288-96. PMID: 8940274; PMCID: PMC1914874.
      Citations: 5     Fields:    Translation:HumansCells
    170. Wasserman D, Hoekstra JH, Tolia V, Taylor CJ, Kirschner BS, Takeda J, Bell GI, Taub R, Rand EB. Molecular analysis of the fructose transporter gene (GLUT5) in isolated fructose malabsorption. J Clin Invest. 1996 Nov 15; 98(10):2398-402. PMID: 8941659; PMCID: PMC507692.
      Citations: 24     Fields:    Translation:Humans
    171. Byrne MM, Sturis J, Menzel S, Yamagata K, Fajans SS, Dronsfield MJ, Bain SC, Hattersley AT, Velho G, Froguel P, Bell GI, Polonsky KS. Altered insulin secretory responses to glucose in diabetic and nondiabetic subjects with mutations in the diabetes susceptibility gene MODY3 on chromosome 12. Diabetes. 1996 Nov; 45(11):1503-10. PMID: 8866553.
      Citations: 58     Fields:    Translation:HumansCells
    172. Ghani AC, Ison CA, Ward H, Garnett GP, Bell G, Kinghorn GR, Weber J, Day S. Sexual partner networks in the transmission of sexually transmitted diseases. An analysis of gonorrhea cases in Sheffield, UK. Sex Transm Dis. 1996 Nov-Dec; 23(6):498-503. PMID: 8946636.
      Citations: 11     Fields:    Translation:HumansCellsPHPublic Health
    173. Hino A, Tokuyama Y, Weir B, Takeda J, Yano H, Bell GI, Macdonald RL. Changes in endothelial nitric oxide synthase mRNA during vasospasm after subarachnoid hemorrhage in monkeys. Neurosurgery. 1996 Sep; 39(3):562-7; discussion 567-8. PMID: 8875487.
      Citations: 17     Fields:    Translation:Animals
    174. Fajans SS, Bell GI, Bowden DW, Halter JB, Polonsky KS. Maturity onset diabetes of the young (MODY). Diabet Med. 1996 Sep; 13(9 Suppl 6):S90-5. PMID: 8894490.
      Citations: 4     Fields:    Translation:HumansCells
    175. Capra F, Veglia F, Ferrari M, Xiang KS, Bell GI, Baroni MG, Galton DJ, Weaver JU, Hitman GA, Kopelman PG, Mohan V, Viswanathan M, Pontiroli AE. Genetic contribution of polymorphism of the GLUT1 and GLUT4 genes to the susceptibility to type 2 (non-insulin-dependent) diabetes mellitus in different populations. Acta Diabetol. 1996 Sep; 33(3):193-7. PMID: 8904924.
      Citations: 7     Fields:    Translation:Humans
    176. Furuta H, Nishi S, Le Beau MM, Fernald AA, Yano H, Bell GI. Sequence of human hexokinase III cDNA and assignment of the human hexokinase III gene (HK3) to chromosome band 5q35.2 by fluorescence in situ hybridization. Genomics. 1996 Aug 15; 36(1):206-9. PMID: 8812439.
      Citations: 7     Fields:    Translation:HumansCells
    177. Bell G, Green DM, Zeyl C. Sex and the spread of retrotransposon Ty3 in experimental populations of Saccharomyces cerevisiae. Genetics. 1996 Aug; 143(4):1567-77. PMID: 8844146; PMCID: PMC1207421.
      Citations: 19     Fields:    Translation:AnimalsCells
    178. Glaum SR, Hara M, Bindokas VP, Lee CC, Polonsky KS, Bell GI, Miller RJ. Leptin, the obese gene product, rapidly modulates synaptic transmission in the hypothalamus. Mol Pharmacol. 1996 Aug; 50(2):230-5. PMID: 8700128.
      Citations: 23     Fields:    Translation:AnimalsCells
    179. Hino A, Tokuyama Y, Kobayashi M, Yano M, Weir B, Takeda J, Wang X, Bell GI, Macdonald RL. Increased expression of endothelin B receptor mRNA following subarachnoid hemorrhage in monkeys. J Cereb Blood Flow Metab. 1996 Jul; 16(4):688-97. PMID: 8964809.
      Citations: 7     Fields:    Translation:AnimalsCells
    180. Hanis CL, Boerwinkle E, Chakraborty R, Ellsworth DL, Concannon P, Stirling B, Morrison VA, Wapelhorst B, Spielman RS, Gogolin-Ewens KJ, Shepard JM, Williams SR, Risch N, Hinds D, Iwasaki N, Ogata M, Omori Y, Petzold C, Rietzch H, Schulze J, Cox NJ, Menzel S, Boriraj VV, Chen X, Lim LR, Lindner T, Mereu LE, Wang YQ, Xiang K, Yamagata K, Yang Y, Bell GI, Schröder HE. A genome-wide search for human non-insulin-dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2. Nat Genet. 1996 Jun; 13(2):161-6. PMID: 8640221.
      Citations: 118     Fields:    Translation:HumansCells
    181. Yamagata K, Takeda J, Menzel S, Chen X, Eng S, Lim LR, Concannon P, Hanis CL, Spielman RS, Cox NJ, Bell GI. Searching for NIDDM susceptibility genes: studies of genes with triplet repeats expressed in skeletal muscle. Diabetologia. 1996 Jun; 39(6):725-30. PMID: 8781769.
      Citations:    Fields:    Translation:HumansCells
    182. Miller RJ, Bell GI. JAK/STAT eats the fat. Trends Neurosci. 1996 May; 19(5):159-61. PMID: 8723197.
      Citations: 5     Fields:    Translation:Animals
    183. Stoffel M, Le Beau MM, Espinosa R, Bohlander SF, Le Paslier D, Cohen D, Xiang KS, Cox NJ, Fajans SS, Bell GI. A yeast artificial chromosome-based map of the region of chromosome 20 containing the diabetes-susceptibility gene, MODY1, and a myeloid leukemia related gene. Proc Natl Acad Sci U S A. 1996 Apr 30; 93(9):3937-41. PMID: 8632993; PMCID: PMC39463.
      Citations: 6     Fields:    Translation:HumansCells
    184. DeLisle S, Blondel O, Longo FJ, Schnabel WE, Bell GI, Welsh MJ. Expression of inositol 1,4,5-trisphosphate receptors changes the Ca2+ signal of Xenopus oocytes. Am J Physiol. 1996 Apr; 270(4 Pt 1):C1255-61. PMID: 8928753.
      Citations: 16     Fields:    Translation:AnimalsCells
    185. Tokuyama Y, Fan Z, Furuta H, Makielski JC, Polonsky KS, Bell GI, Yano H. Rat inwardly rectifying potassium channel Kir6.2: cloning electrophysiological characterization, and decreased expression in pancreatic islets of male Zucker diabetic fatty rats. Biochem Biophys Res Commun. 1996 Mar 27; 220(3):532-8. PMID: 8607800.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    186. Polonsky KS, Sturis J, Bell GI. Seminars in Medicine of the Beth Israel Hospital, Boston. Non-insulin-dependent diabetes mellitus - a genetically programmed failure of the beta cell to compensate for insulin resistance. N Engl J Med. 1996 Mar 21; 334(12):777-83. PMID: 8592553.
      Citations: 101     Fields:    Translation:HumansAnimals
    187. Gambino V, Menzel S, Trabb JB, Xiang KS, Lindner T, Chen E, Mereu LE, Furuta H, Iwasaki N, Kawamura M, Omori Y, Rietzsch H, Schulze J, Concannon P, Hanis CL, Spielman RS, Yamagata K, Cox NJ, Bell GI, Louït A, Schröder HE. An approach for identifying simple sequence repeat DNA polymorphisms near cloned cDNAs and genes. Linkage studies of the islet amyloid polypeptide/amylin and liver glycogen synthase genes and NIDDM. Diabetes. 1996 Mar; 45(3):291-4. PMID: 8593932.
      Citations: 2     Fields:    Translation:HumansCells
    188. Reardon DB, Wood SL, Brautigan DL, Bell GI, Dent P, Sturgill TW. Activation of a protein tyrosine phosphatase and inactivation of Raf-1 by somatostatin. Biochem J. 1996 Mar 01; 314 ( Pt 2):401-4. PMID: 8670047; PMCID: PMC1217062.
      Citations: 7     Fields:    Translation:AnimalsCells
    189. Lane RH, Flozak AS, Ogata ES, Bell GI, Simmons RA. Altered hepatic gene expression of enzymes involved in energy metabolism in the growth-retarded fetal rat. Pediatr Res. 1996 Mar; 39(3):390-4. PMID: 8929856.
      Citations: 26     Fields:    Translation:AnimalsCells
    190. Bell GI. Evolution of simple sequence repeats. Comput Chem. 1996 Mar; 20(1):41-8. PMID: 8867840.
      Citations: 6     Fields:    Translation:HumansCells
    191. Iwasaki N, Kawamura M, Yamagata K, Cox NJ, Karibe S, Ohgawara H, Inagaki N, Seino S, Bell GI, Omori Y. Identification of microsatellite markers near the human genes encoding the beta-cell ATP-sensitive K+ channel and linkage studies with NIDDM in Japanese. Diabetes. 1996 Feb; 45(2):267-9. PMID: 8549873.
      Citations: 3     Fields:    Translation:HumansCells
    192. Becker TC, Noel RJ, Johnson JH, Lynch RM, Hirose H, Tokuyama Y, Bell GI, Newgard CB. Differential effects of overexpressed glucokinase and hexokinase I in isolated islets. Evidence for functional segregation of the high and low Km enzymes. J Biol Chem. 1996 Jan 05; 271(1):390-4. PMID: 8550593.
      Citations: 21     Fields:    Translation:AnimalsCells
    193. Roe MW, Worley JF, Tokuyama Y, Philipson LH, Sturis J, Tang J, Dukes ID, Bell GI, Polonsky KS. NIDDM is associated with loss of pancreatic beta-cell L-type Ca2+ channel activity. Am J Physiol. 1996 Jan; 270(1 Pt 1):E133-40. PMID: 8772485.
      Citations: 16     Fields:    Translation:AnimalsCells
    194. Bell GI, Pilkis SJ, Weber IT, Polonsky KS. Glucokinase mutations, insulin secretion, and diabetes mellitus. Annu Rev Physiol. 1996; 58:171-86. PMID: 8815790.
      Citations: 24     Fields:    Translation:HumansAnimals
    195. Tokuyama Y, Sturis J, DePaoli AM, Takeda J, Stoffel M, Tang J, Sun X, Polonsky KS, Bell GI. Evolution of beta-cell dysfunction in the male Zucker diabetic fatty rat. Diabetes. 1995 Dec; 44(12):1447-57. PMID: 7589853.
      Citations: 78     Fields:    Translation:AnimalsCells
    196. Lehto M, Huang X, Davis EM, Le Beau MM, Laurila E, Eriksson KF, Bell GI, Groop L. Human hexokinase II gene: exon-intron organization, mutation screening in NIDDM, and its relationship to muscle hexokinase activity. Diabetologia. 1995 Dec; 38(12):1466-74. PMID: 8786021.
      Citations: 3     Fields:    Translation:HumansCells
    197. Stirling B, Cox NJ, Bell GI, Hanis CL, Spielman RS, Concannon P. Linkage studies in NIDDM with markers near the sulphonylurea receptor gene. Diabetologia. 1995 Dec; 38(12):1479-81. PMID: 8786023.
      Citations: 3     Fields:    Translation:HumansCells
    198. Zhang Y, Warren-Perry M, Saker PJ, Hattersley AT, Mackie AD, Baird JD, Greenwood RH, Stoffel M, Bell GI, Turner RC. Candidate gene studies in pedigrees with maturity-onset diabetes of the young not linked with glucokinase. Diabetologia. 1995 Sep; 38(9):1055-60. PMID: 8591819.
      Citations: 2     Fields:    Translation:HumansCells
    199. Takeda J, Espinosa R, Eng S, Le Beau MM, Bell GI. Chromosomal assignment and tissue distribution of novel expressed sequence tags from a human pancreatic islet cDNA library. Genomics. 1995 Sep 01; 29(1):276-81. PMID: 8530086.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    200. Stoffel M, Fernald AA, Le Beau MM, Bell GI. Assignment of the gastric inhibitory polypeptide receptor gene (GIPR) to chromosome bands 19q13.2-q13.3 by fluorescence in situ hybridization. Genomics. 1995 Aug 10; 28(3):607-9. PMID: 7490109.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    201. Stirling B, Cox NJ, Bell GI, Hanis CL, Spielman RS, Concannon P. Identification of microsatellite markers near the human ob gene and linkage studies in NIDDM-affected sib pairs. Diabetes. 1995 Aug; 44(8):999-1001. PMID: 7622007.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    202. Reisine T, Bell GI. Molecular properties of somatostatin receptors. Neuroscience. 1995 Aug; 67(4):777-90. PMID: 7675204.
      Citations: 35     Fields:    Translation:Animals
    203. Reisine T, Bell GI. Molecular biology of somatostatin receptors. Endocr Rev. 1995 Aug; 16(4):427-42. PMID: 8521788.
      Citations: 97     Fields:    Translation:HumansAnimalsCells
    204. Stoffel M, Tokuyama Y, Trabb JB, German MS, Tsaar ML, Jan LY, Polonsky KS, Bell GI. Cloning of rat KATP-2 channel and decreased expression in pancreatic islets of male Zucker diabetic fatty rats. Biochem Biophys Res Commun. 1995 Jul 26; 212(3):894-9. PMID: 7626127.
      Citations: 5     Fields:    Translation:AnimalsCells
    205. Stoffel M, Stein R, Wright CV, Espinosa R, Le Beau MM, Bell GI. Localization of human homeodomain transcription factor insulin promoter factor 1 (IPF1) to chromosome band 13q12.1. Genomics. 1995 Jul 01; 28(1):125-6. PMID: 7590740.
      Citations: 7     Fields:    Translation:HumansCells
    206. el-Maghrabi MR, Lange AJ, Jiang W, Yamagata K, Stoffel M, Takeda J, Fernald AA, Le Beau MM, Bell GI, Baker L, et al. Human fructose-1,6-bisphosphatase gene (FBP1): exon-intron organization, localization to chromosome bands 9q22.2-q22.3, and mutation screening in subjects with fructose-1,6-bisphosphatase deficiency. Genomics. 1995 Jun 10; 27(3):520-5. PMID: 7558035.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    207. Tokuyama Y, Hara M, Jones EM, Fan Z, Bell GI. Cloning of rat and mouse P2Y purinoceptors. Biochem Biophys Res Commun. 1995 Jun 06; 211(1):211-8. PMID: 7779087.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    208. Byrne MM, Sturis J, Fajans SS, Ortiz FJ, Stoltz A, Stoffel M, Smith MJ, Bell GI, Halter JB, Polonsky KS. Altered insulin secretory responses to glucose in subjects with a mutation in the MODY1 gene on chromosome 20. Diabetes. 1995 Jun; 44(6):699-704. PMID: 7789636.
      Citations: 36     Fields:    Translation:HumansCells
    209. Rowe RE, Wapelhorst B, Bell GI, Risch N, Spielman RS, Concannon P. Linkage and association between insulin-dependent diabetes mellitus (IDDM) susceptibility and markers near the glucokinase gene on chromosome 7. Nat Genet. 1995 Jun; 10(2):240-2. PMID: 7663523.
      Citations: 6     Fields:    Translation:HumansCells
    210. Zhang Y, Warren-Perry M, Sakura H, Adelman J, Stoffel M, Bell GI, Ashcroft FM, Turner RC. No evidence for mutations in a putative beta-cell ATP-sensitive K+ channel subunit in MODY, NIDDM, or GDM. Diabetes. 1995 May; 44(5):597-600. PMID: 7729622.
      Citations: 3     Fields:    Translation:Humans
    211. Takeda J, Fernald AA, Yamagata K, Le Beau MM, Bell GI. Localization of human somatostatin receptor 5 gene (SSTR5) to chromosome band 16p13.3 by fluorescence in situ hybridization. Genomics. 1995 Apr 10; 26(3):638-9. PMID: 7607700.
      Citations: 3     Fields:    Translation:HumansCells
    212. Blondel O, Bell GI, Seino S. Inositol 1,4,5-trisphosphate receptors, secretory granules and secretion in endocrine and neuroendocrine cells. Trends Neurosci. 1995 Apr; 18(4):157-61. PMID: 7778186.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    213. Page RC, Hattersley AT, Levy JC, Barrow B, Patel P, Lo D, Wainscoat JS, Permutt MA, Bell GI, Turner RC. Clinical characteristics of subjects with a missense mutation in glucokinase. Diabet Med. 1995 Mar; 12(3):209-17. PMID: 7758256.
      Citations: 11     Fields:    Translation:Humans
    214. Hoyer D, Bell GI, Berelowitz M, Epelbaum J, Feniuk W, Humphrey PP, O'Carroll AM, Patel YC, Schonbrunn A, Taylor JE, et al. Classification and nomenclature of somatostatin receptors. Trends Pharmacol Sci. 1995 Mar; 16(3):86-8. PMID: 7792934.
      Citations: 121     Fields:    Translation:Cells
    215. Iwasaki N, Ohgawara H, Nagahara H, Kawamura M, Bell GI, Omori Y. Characterization of Japanese families with early-onset type 2 (non-insulin dependent) diabetes mellitus and screening for mutations in the glucokinase and mitochondrial tRNA(Leu(UUR)) genes. Acta Diabetol. 1995 Mar; 32(1):17-22. PMID: 7542040.
      Citations: 2     Fields:    Translation:HumansCells
    216. Saint-Laurent N, Bertrand V, Reisine T, O'Carroll AM, Bell GI, Schally AV, Vaysse N, Susini C, Buscail L, Estève JP. Inhibition of cell proliferation by the somatostatin analogue RC-160 is mediated by somatostatin receptor subtypes SSTR2 and SSTR5 through different mechanisms. Proc Natl Acad Sci U S A. 1995 Feb 28; 92(5):1580-4. PMID: 7878022; PMCID: PMC42563.
      Citations: 56     Fields:    Translation:AnimalsCells
    217. Wilson BD, Ollmann MM, Kang L, Stoffel M, Bell GI, Barsh GS. Structure and function of ASP, the human homolog of the mouse agouti gene. Hum Mol Genet. 1995 Feb; 4(2):223-30. PMID: 7757071.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    218. Shimada F, Makino H, Iwaoka H, Miyamoto S, Hashimoto N, Kanatsuka A, Bell GI, Yoshida S. Identification of two novel amino acid polymorphisms in beta-cell/liver (GLUT2) glucose transporter in Japanese subjects. Diabetologia. 1995 Feb; 38(2):211-5. PMID: 7713316.
      Citations: 2     Fields:    Translation:HumansCells
    219. Xiang K, Wu S, Wang Y, Sun D, Zhang R, Xu J, Huang Q, Karam JH, Bell GI. The population association of glucokinase gene with type 2 (noninsulin-dependent) diabetes mellitus in Chinese. Chin Med J (Engl). 1995 Jan; 108(1):5-9. PMID: 7712840.
      Citations:    Fields:    Translation:HumansCells
    220. Jones EM, Fernald A, Bell GI, Le Beau MM. Assignment of SLC6A9 to human chromosome band 1p33 by in situ hybridization. Cytogenet Cell Genet. 1995; 71(3):211. PMID: 7587377.
      Citations: 3     Fields:    Translation:HumansCells
    221. Delesque N, Buscail L, Rauly I, Zeggari M, Saint-Laurent N, Bell GI, Schally AV, Vaysse N, Susini C, Estève JP. A tyrosine phosphatase is associated with the somatostatin receptor. Ciba Found Symp. 1995; 190:187-96; discussion 196-203. PMID: 7587647.
      Citations:    Fields:    Translation:AnimalsCells
    222. Bell GI, Yasuda K, Kong H, Law SF, Raynor K, Reisine T. Molecular biology of somatostatin receptors. Ciba Found Symp. 1995; 190:65-79; discussion 80-8. PMID: 7587653.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    223. Wapelhorst B, Bell GI, Risch N, Spielman RS, Concannon P. Linkage and association studies in insulin-dependent diabetes with a new dinucleotide repeat polymorphism at the GAD65 locus. Autoimmunity. 1995; 21(2):127-30. PMID: 8679901.
      Citations: 1     Fields:    Translation:HumansCells
    224. Tallent M, Dichter MA, Bell GI, Reisine T. The cloned kappa opioid receptor couples to an N-type calcium current in undifferentiated PC-12 cells. Neuroscience. 1994 Dec; 63(4):1033-40. PMID: 7700508.
      Citations: 28     Fields:    Translation:AnimalsCells
    225. DePaoli AM, Bell GI, Stoffel M. G protein-activated inwardly rectifying potassium channel (GIRK1/KGA) mRNA in adult rat heart and brain by in situ hybridization histochemistry. Mol Cell Neurosci. 1994 Dec; 5(6):515-22. PMID: 7704424.
      Citations: 9     Fields:    Translation:AnimalsCells
    226. German MS, Wang J, Fernald AA, Espinosa R, Le Beau MM, Bell GI. Localization of the genes encoding two transcription factors, LMX1 and CDX3, regulating insulin gene expression to human chromosomes 1 and 13. Genomics. 1994 Nov 15; 24(2):403-4. PMID: 7698771.
      Citations: 22     Fields:    Translation:HumansCells
    227. Blondel O, Bell GI, Moody M, Miller RJ, Gibbons SJ. Creation of an inositol 1,4,5-trisphosphate-sensitive Ca2+ store in secretory granules of insulin-producing cells. J Biol Chem. 1994 Nov 04; 269(44):27167-70. PMID: 7961623.
      Citations: 19     Fields:    Translation:AnimalsCells
    228. Stoffel M, Espinosa R, Trabb JB, Le Beau MM, Bell GI. Human type I pituitary adenylate cyclase activating polypeptide receptor (ADCYAP1R): localization to chromosome band 7p14 and integration into the cytogenetic, physical, and genetic map of chromosome 7. Genomics. 1994 Oct; 23(3):697-9. PMID: 7851900.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    229. Jones EM, Menzel S, Espinosa R, Le Beau MM, Bell GI, Takeda J. Localization of the gene encoding a neutral amino acid transporter-like protein to human chromosome band 19q13.3 and characterization of a simple sequence repeat DNA polymorphism. Genomics. 1994 Sep 15; 23(2):490-1. PMID: 7835902.
      Citations: 3     Fields:    Translation:HumansCells
    230. Pilkis SJ, Weber IT, Harrison RW, Bell GI. Glucokinase: structural analysis of a protein involved in susceptibility to diabetes. J Biol Chem. 1994 Sep 02; 269(35):21925-8. PMID: 8071309.
      Citations: 20     Fields:    Translation:HumansCells
    231. Raynor K, Kong H, Hines J, Kong G, Benovic J, Yasuda K, Bell GI, Reisine T. Molecular mechanisms of agonist-induced desensitization of the cloned mouse kappa opioid receptor. J Pharmacol Exp Ther. 1994 Sep; 270(3):1381-6. PMID: 7932192.
      Citations: 8     Fields:    Translation:AnimalsCells
    232. Kong H, Raynor K, Yano H, Takeda J, Bell GI, Reisine T. Agonists and antagonists bind to different domains of the cloned kappa opioid receptor. Proc Natl Acad Sci U S A. 1994 Aug 16; 91(17):8042-6. PMID: 8058754; PMCID: PMC44541.
      Citations: 9     Fields:    Translation:AnimalsCells
    233. Blondel O, Moody MM, Depaoli AM, Sharp AH, Ross CA, Swift H, Bell GI. Localization of inositol trisphosphate receptor subtype 3 to insulin and somatostatin secretory granules and regulation of expression in islets and insulinoma cells. Proc Natl Acad Sci U S A. 1994 Aug 02; 91(16):7777-81. PMID: 7914371; PMCID: PMC44485.
      Citations: 25     Fields:    Translation:AnimalsCells
    234. DePaoli AM, Hurley KM, Yasada K, Reisine T, Bell G. Distribution of kappa opioid receptor mRNA in adult mouse brain: an in situ hybridization histochemistry study. Mol Cell Neurosci. 1994 Aug; 5(4):327-35. PMID: 7804602.
      Citations: 46     Fields:    Translation:Animals
    235. Theveniau MA, Yasuda K, Bell GI, Reisine T. Immunological detection of isoforms of the somatostatin receptor subtype, SSTR2. J Neurochem. 1994 Aug; 63(2):447-55. PMID: 7518495.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    236. Takeda J, Mesonero J, Chantret I, Dussaulx E, Bell GI, Brot-Laroche E, Mahraoui L. Regulation of expression of the human fructose transporter (GLUT5) by cyclic AMP. Biochem J. 1994 Jul 01; 301 ( Pt 1):169-75. PMID: 8037665; PMCID: PMC1137157.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    237. St Charles R, Harrison RW, Bell GI, Pilkis SJ, Weber IT. Molecular model of human beta-cell glucokinase built by analogy to the crystal structure of yeast hexokinase B. Diabetes. 1994 Jun; 43(6):784-91. PMID: 8194664.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    238. Sturis J, Kurland IJ, Byrne MM, Mosekilde E, Froguel P, Pilkis SJ, Bell GI, Polonsky KS. Compensation in pancreatic beta-cell function in subjects with glucokinase mutations. Diabetes. 1994 May; 43(5):718-23. PMID: 8168650.
      Citations: 12     Fields:    Translation:HumansCells
    239. Stoffel M, Espinosa R, Powell KL, Philipson LH, Le Beau MM, Bell GI. Human G-protein-coupled inwardly rectifying potassium channel (GIRK1) gene (KCNJ3): localization to chromosome 2 and identification of a simple tandem repeat polymorphism. Genomics. 1994 May 01; 21(1):254-6. PMID: 8088798.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    240. Yano H, Philipson LH, Kugler JL, Tokuyama Y, Davis EM, Le Beau MM, Nelson DJ, Bell GI, Takeda J. Alternative splicing of human inwardly rectifying K+ channel ROMK1 mRNA. Mol Pharmacol. 1994 May; 45(5):854-60. PMID: 8190102.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    241. Law SF, Zaina S, Sweet R, Yasuda K, Bell GI, Stadel J, Reisine T. Gi alpha 1 selectively couples somatostatin receptor subtype 3 to adenylyl cyclase: identification of the functional domains of this alpha subunit necessary for mediating the inhibition by somatostatin of cAMP formation. Mol Pharmacol. 1994 Apr; 45(4):587-90. PMID: 8183236.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    242. Menzel S, Stoffel M, Espinosa R, Fernald AA, Le Beau MM, Bell GI. Localization of the glucagon receptor gene to human chromosome band 17q25. Genomics. 1994 Mar 15; 20(2):327-8. PMID: 8020989.
      Citations: 3     Fields:    Translation:HumansCells
    243. Delesque N, Saint-Laurent N, Prats H, Clerc P, Robberecht P, Bell GI, Liebow C, Schally AV, Buscail L, Estève JP, et al. Stimulation of tyrosine phosphatase and inhibition of cell proliferation by somatostatin analogues: mediation by human somatostatin receptor subtypes SSTR1 and SSTR2. Proc Natl Acad Sci U S A. 1994 Mar 15; 91(6):2315-9. PMID: 7907795; PMCID: PMC43361.
      Citations: 46     Fields:    Translation:HumansAnimalsCells
    244. Kong H, DePaoli AM, Breder CD, Yasuda K, Bell GI, Reisine T. Differential expression of messenger RNAs for somatostatin receptor subtypes SSTR1, SSTR2 and SSTR3 in adult rat brain: analysis by RNA blotting and in situ hybridization histochemistry. Neuroscience. 1994 Mar; 59(1):175-84. PMID: 8190266.
      Citations: 23     Fields:    Translation:Animals
    245. Nishi S, Hinata S, Matsukage T, Takeda J, Ichiyama A, Bell GI, Yoshimi T. Mutations in the glucokinase gene are not a major cause of late-onset type 2 (non-insulin-dependent) diabetes mellitus in Japanese subjects. Diabet Med. 1994 Mar; 11(2):193-7. PMID: 8200206.
      Citations: 1     Fields:    Translation:HumansCells
    246. Byrne MM, Sturis J, Vionnet N, Pueyo ME, Stoffel M, Takeda J, Passa P, Cohen D, Bell GI, Clément K, et al. Insulin secretory abnormalities in subjects with hyperglycemia due to glucokinase mutations. J Clin Invest. 1994 Mar; 93(3):1120-30. PMID: 8132752; PMCID: PMC294056.
      Citations: 77     Fields:    Translation:Humans
    247. Takeda J, Blackburn CL, Menzel S, Yano H, Bell GI. Dinucleotide repeat polymorphism at D9S328E (EST hbc220). Hum Mol Genet. 1994 Feb; 3(2):387. PMID: 8004124.
      Citations:    Fields:    Translation:HumansCells
    248. Yasuda K, Espinosa R, Takeda J, Le Beau MM, Bell GI. Localization of the kappa opioid receptor gene to human chromosome band 8q11.2. Genomics. 1994 Feb; 19(3):596-7. PMID: 8188308.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    249. Raynor K, Kong H, Chen Y, Yasuda K, Yu L, Bell GI, Reisine T. Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors. Mol Pharmacol. 1994 Feb; 45(2):330-4. PMID: 8114680.
      Citations: 193     Fields:    Translation:AnimalsCells
    250. Rigo M, Kaupmann K, Bruns C, Yasuda K, Bell GI, Hoyer D, Pérez J, Lübbert H. Localization of somatostatin (SRIF) SSTR-1, SSTR-2 and SSTR-3 receptor mRNA in rat brain by in situ hybridization. Naunyn Schmiedebergs Arch Pharmacol. 1994 Feb; 349(2):145-60. PMID: 8170498.
      Citations: 22     Fields:    Translation:Animals
    251. Herman WH, Fajans SS, Ortiz FJ, Smith MJ, Sturis J, Bell GI, Polonsky KS, Halter JB. Abnormal insulin secretion, not insulin resistance, is the genetic or primary defect of MODY in the RW pedigree. Diabetes. 1994 Jan; 43(1):40-6. PMID: 8262315.
      Citations: 16     Fields:    Translation:HumansCells
    252. Fajans SS, Bell GI, Bowden DW, Halter JB, Polonsky KS. Maturity-onset diabetes of the young. Life Sci. 1994; 55(6):413-22. PMID: 8035658.
      Citations: 10     Fields:    Translation:Humans
    253. Lehto M, Xiang K, Stoffel M, Espinosa R, Groop LC, Le Beau MM, Bell GI. Human hexokinase II: localization of the polymorphic gene to chromosome 2. Diabetologia. 1993 Dec; 36(12):1299-302. PMID: 8307259.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    254. Roulston D, Espinosa R, Stoffel M, Bell GI, Le Beau MM. Molecular genetics of myeloid leukemia: identification of the commonly deleted segment of chromosome 20. Blood. 1993 Dec 01; 82(11):3424-9. PMID: 8241509.
      Citations: 7     Fields:    Translation:HumansCells
    255. Reisine T, Bell GI. Molecular biology of opioid receptors. Trends Neurosci. 1993 Dec; 16(12):506-10. PMID: 7509520.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    256. Kong H, Raynor K, Yasuda K, Moe ST, Portoghese PS, Bell GI, Reisine T. A single residue, aspartic acid 95, in the delta opioid receptor specifies selective high affinity agonist binding. J Biol Chem. 1993 Nov 05; 268(31):23055-8. PMID: 8226821.
      Citations: 27     Fields:    Translation:AnimalsCells
    257. Seo TS, Hanabusa T, Ohagi S, Steiner DF, Bell GI. Dinucleotide repeat polymorphism in the NEC2 gene. Hum Mol Genet. 1993 Nov; 2(11):1983. PMID: 8281173.
      Citations:    Fields:    Translation:HumansCells
    258. Takeda J, Yano H, Eng S, Zeng Y, Bell GI. A molecular inventory of human pancreatic islets: sequence analysis of 1000 cDNA clones. Hum Mol Genet. 1993 Nov; 2(11):1793-8. PMID: 7506601.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    259. Reisine T, Kong H, Raynor K, Yano H, Takeda J, Yasuda K, Bell GI. Splice variant of the somatostatin receptor 2 subtype, somatostatin receptor 2B, couples to adenylyl cyclase. Mol Pharmacol. 1993 Nov; 44(5):1016-20. PMID: 7902529.
      Citations: 14     Fields:    Translation:AnimalsCells
    260. Bell GI, Burant CF, Takeda J, Gould GW. Structure and function of mammalian facilitative sugar transporters. J Biol Chem. 1993 Sep 15; 268(26):19161-4. PMID: 8366068.
      Citations: 96     Fields:    Translation:HumansAnimalsCells
    261. Yasuda K, Espinosa R, Davis EM, Le Beau MM, Bell GI. Human somatostatin receptor genes: localization of SSTR5 to human chromosome 20p11.2. Genomics. 1993 Sep; 17(3):785-6. PMID: 8244401.
      Citations: 1     Fields:    Translation:HumansCells
    262. Raynor K, O'Carroll AM, Kong H, Yasuda K, Mahan LC, Bell GI, Reisine T. Characterization of cloned somatostatin receptors SSTR4 and SSTR5. Mol Pharmacol. 1993 Aug; 44(2):385-92. PMID: 8102785.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    263. Kong H, Raynor K, Yasuda K, Bell GI, Reisine T. Mutation of an aspartate at residue 89 in somatostatin receptor subtype 2 prevents Na+ regulation of agonist binding but does not alter receptor-G protein association. Mol Pharmacol. 1993 Aug; 44(2):380-4. PMID: 8102784.
      Citations: 16     Fields:    Translation:AnimalsCells
    264. Stoffel M, Espinosa R, Le Beau MM, Bell GI. Human glucagon-like peptide-1 receptor gene. Localization to chromosome band 6p21 by fluorescence in situ hybridization and linkage of a highly polymorphic simple tandem repeat DNA polymorphism to other markers on chromosome 6. Diabetes. 1993 Aug; 42(8):1215-8. PMID: 8392011.
      Citations: 20     Fields:    Translation:HumansCells
    265. Hayashi Y, Mori Y, Janssen OE, Sunthornthepvarakul T, Weiss RE, Takeda K, Weinberg M, Seo H, Bell GI, Refetoff S. Human thyroxine-binding globulin gene: complete sequence and transcriptional regulation. Mol Endocrinol. 1993 Aug; 7(8):1049-60. PMID: 8232304.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    266. Yasuda K, Raynor K, Kong H, Breder CD, Takeda J, Reisine T, Bell GI. Cloning and functional comparison of kappa and delta opioid receptors from mouse brain. Proc Natl Acad Sci U S A. 1993 Jul 15; 90(14):6736-40. PMID: 8393575; PMCID: PMC47007.
      Citations: 104     Fields:    Translation:AnimalsCells
    267. Iwashima Y, Pugh W, Depaoli AM, Takeda J, Seino S, Bell GI, Polonsky KS. Expression of calcium channel mRNAs in rat pancreatic islets and downregulation after glucose infusion. Diabetes. 1993 Jul; 42(7):948-55. PMID: 7685720.
      Citations: 23     Fields:    Translation:AnimalsCells
    268. Rand EB, Depaoli AM, Davidson NO, Bell GI, Burant CF. Sequence, tissue distribution, and functional characterization of the rat fructose transporter GLUT5. Am J Physiol. 1993 Jun; 264(6 Pt 1):G1169-76. PMID: 8333543.
      Citations: 53     Fields:    Translation:AnimalsCells
    269. Vionnet N, Bell GI. Identification of a simple tandem repeat DNA polymorphism in the human glycogen synthase gene and linkage to five markers on chromosome 19q. Diabetes. 1993 Jun; 42(6):930-2. PMID: 8495815.
      Citations: 3     Fields:    Translation:HumansCells
    270. Raynor K, Murphy WA, Coy DH, Taylor JE, Moreau JP, Yasuda K, Bell GI, Reisine T. Cloned somatostatin receptors: identification of subtype-selective peptides and demonstration of high affinity binding of linear peptides. Mol Pharmacol. 1993 Jun; 43(6):838-44. PMID: 8100350.
      Citations: 40     Fields:    Translation:AnimalsCells
    271. Blondel O, Takeda J, Janssen H, Seino S, Bell GI. Sequence and functional characterization of a third inositol trisphosphate receptor subtype, IP3R-3, expressed in pancreatic islets, kidney, gastrointestinal tract, and other tissues. J Biol Chem. 1993 May 25; 268(15):11356-63. PMID: 8388391.
      Citations: 91     Fields:    Translation:AnimalsCells
    272. Law SF, Yasuda K, Bell GI, Reisine T. Gi alpha 3 and G(o) alpha selectively associate with the cloned somatostatin receptor subtype SSTR2. J Biol Chem. 1993 May 25; 268(15):10721-7. PMID: 8098703.
      Citations: 37     Fields:    Translation:AnimalsCells
    273. Olson AL, Liu ML, Moye-Rowley WS, Buse JB, Bell GI, Pessin JE. Hormonal/metabolic regulation of the human GLUT4/muscle-fat facilitative glucose transporter gene in transgenic mice. J Biol Chem. 1993 May 05; 268(13):9839-46. PMID: 8486663.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    274. Shimada F, Makino H, Hashimoto N, Taira M, Seino S, Bell GI, Kanatsuka A, Yoshida S. Type 2 (non-insulin-dependent) diabetes mellitus associated with a mutation of the glucokinase gene in a Japanese family. Diabetologia. 1993 May; 36(5):433-7. PMID: 8314448.
      Citations: 7     Fields:    Translation:HumansCells
    275. Takeda J, Kayano T, Fukomoto H, Bell GI. Organization of the human GLUT2 (pancreatic beta-cell and hepatocyte) glucose transporter gene. Diabetes. 1993 May; 42(5):773-7. PMID: 8482435.
      Citations: 15     Fields:    Translation:HumansCells
    276. Stoffel M, Espinosa R, Keller SR, Lienhard GE, Le Beau MM, Bell GI. Human insulin receptor substrate-1 gene (IRS1): chromosomal localization to 2q35-q36.1 and identification of a simple tandem repeat DNA polymorphism. Diabetologia. 1993 Apr; 36(4):335-7. PMID: 8477879.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    277. Bell GI, Froguel P, Nishi S, Pilkis SJ, Stoffel M, Takeda J, Vionnet N, Yasuda K. Mutations of the human glucokinase gene and diabetes mellitus. Trends Endocrinol Metab. 1993 Apr; 4(3):86-90. PMID: 18407139.
      Citations: 2     Fields:    
    278. Lehto M, Stoffel M, Groop L, Espinosa R, Le Beau MM, Bell GI. Assignment of the gene encoding glycogen synthase (GYS) to human chromosome 19, band q13.3. Genomics. 1993 Feb; 15(2):460-1. PMID: 8449521.
      Citations: 7     Fields:    Translation:HumansCells
    279. Stoffel M, Bell GI. Characterization of a third simple tandem repeat polymorphism in the human glucokinase gene. Diabetologia. 1993 Feb; 36(2):170-1. PMID: 8458532.
      Citations:    Fields:    Translation:HumansCells
    280. Yamada Y, Stoffel M, Espinosa R, Xiang KS, Seino M, Seino S, Le Beau MM, Bell GI. Human somatostatin receptor genes: localization to human chromosomes 14, 17, and 22 and identification of simple tandem repeat polymorphisms. Genomics. 1993 Feb; 15(2):449-52. PMID: 8449518.
      Citations: 10     Fields:    Translation:HumansCells
    281. Philipson LH, Eddy RL, Shows TB, Bell GI. Assignment of human potassium channel gene KCNA4 (Kv1.4, PCN2) to chromosome 11q13.4-->q14.1. Genomics. 1993 Feb; 15(2):463-4. PMID: 8449523.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    282. Stoffel M, Xiang KS, Espinosa R, Cox NJ, Le Beau MM, Bell GI. cDNA sequence and localization of polymorphic human cytosolic phosphoenolpyruvate carboxykinase gene (PCK1) to chromosome 20, band q13.31: PCK1 is not tightly linked to maturity-onset diabetes of the young. Hum Mol Genet. 1993 Jan; 2(1):1-4. PMID: 8490617.
      Citations: 5     Fields:    Translation:HumansCells
    283. Bell GI, Reisine T. Molecular biology of somatostatin receptors. Trends Neurosci. 1993 Jan; 16(1):34-8. PMID: 7679236.
      Citations: 47     Fields:    Translation:HumansAnimalsCells
    284. Yamada Y, Reisine T, Law SF, Ihara Y, Kubota A, Kagimoto S, Seino M, Seino Y, Bell GI, Seino S. Somatostatin receptors, an expanding gene family: cloning and functional characterization of human SSTR3, a protein coupled to adenylyl cyclase. Mol Endocrinol. 1992 Dec; 6(12):2136-42. PMID: 1337145.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    285. Buse JB, Yasuda K, Lay TP, Seo TS, Olson AL, Pessin JE, Karam JH, Seino S, Bell GI. Human GLUT4/muscle-fat glucose-transporter gene. Characterization and genetic variation. Diabetes. 1992 Nov; 41(11):1436-45. PMID: 1397719.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    286. Stoffel M, Xiang K, Bell GI. Dinucleotide repeat polymorphism at the human ribophorin II locus (RPN2) on chromosome 20q. Hum Mol Genet. 1992 Nov; 1(8):656. PMID: 1301181.
      Citations:    Fields:    Translation:HumansCells
    287. Burant CF, Bell GI. Mammalian facilitative glucose transporters: evidence for similar substrate recognition sites in functionally monomeric proteins. Biochemistry. 1992 Oct 27; 31(42):10414-20. PMID: 1420159.
      Citations: 69     Fields:    Translation:HumansAnimalsCells
    288. Yasuda K, Rens-Domiano S, Breder CD, Law SF, Saper CB, Reisine T, Bell GI. Cloning of a novel somatostatin receptor, SSTR3, coupled to adenylylcyclase. J Biol Chem. 1992 Oct 05; 267(28):20422-8. PMID: 1328199.
      Citations: 49     Fields:    Translation:AnimalsCells
    289. Sakurai A, Bell GI, DeGroot LJ. Dinucleotide repeat polymorphism in the human thyroid hormone receptor alpha gene (THRA1) on chromosome 17. Hum Mol Genet. 1992 Oct; 1(7):553. PMID: 1307263.
      Citations:    Fields:    Translation:HumansCells
    290. Bowcock AM, Azuma T, Barnes RI, Wu SH, Bell GI, Taggart RT. Detection of a polymorphism within the pepsinogen C gene with PCR: construction of a linkage map around PGC from 6p11-6p21.3. Genomics. 1992 Oct; 14(2):398-402. PMID: 1427855.
      Citations: 2     Fields:    Translation:HumansCells
    291. Breder CD, Yamada Y, Yasuda K, Seino S, Saper CB, Bell GI. Differential expression of somatostatin receptor subtypes in brain. J Neurosci. 1992 Oct; 12(10):3920-34. PMID: 1403090; PMCID: PMC6575973.
      Citations: 36     Fields:    Translation:Animals
    292. Stoffel M, Patel P, Lo YM, Hattersley AT, Lucassen AM, Page R, Bell JI, Bell GI, Turner RC, Wainscoat JS. Missense glucokinase mutation in maturity-onset diabetes of the young and mutation screening in late-onset diabetes. Nat Genet. 1992 Oct; 2(2):153-6. PMID: 1303265.
      Citations: 33     Fields:    Translation:HumansCells
    293. Takeda J, Seino S, Bell GI. Human Oct3 gene family: cDNA sequences, alternative splicing, gene organization, chromosomal location, and expression at low levels in adult tissues. Nucleic Acids Res. 1992 Sep 11; 20(17):4613-20. PMID: 1408763; PMCID: PMC334192.
      Citations: 81     Fields:    Translation:HumansCells
    294. Murray JC, Bennett SR, Kwitek AE, Small KW, Schinzel A, Alward WL, Weber JL, Bell GI, Buetow KH. Linkage of Rieger syndrome to the region of the epidermal growth factor gene on chromosome 4. Nat Genet. 1992 Sep; 2(1):46-9. PMID: 1303248.
      Citations: 21     Fields:    Translation:HumansCells
    295. Patel P, Lo YM, Hattersley A, Bell GI, Tybjaerg-Hansen A, Nerup J, Turner RC, Wainscoat JS. Linkage analysis of maturity-onset diabetes of the young with microsatellite polymorphisms. No linkage to ADA or GLUT2 genes in two families. Diabetes. 1992 Aug; 41(8):962-7. PMID: 1628771.
      Citations: 4     Fields:    Translation:HumansCells
    296. Seino S, Yamada Y, Espinosa R, Le Beau MM, Bell GI. Assignment of the gene encoding the alpha 1 subunit of the neuroendocrine/brain-type calcium channel (CACNL1A2) to human chromosome 3, band p14.3. Genomics. 1992 Aug; 13(4):1375-7. PMID: 1324226.
      Citations:    Fields:    Translation:HumansCells
    297. Nishi S, Stoffel M, Xiang K, Shows TB, Bell GI, Takeda J. Human pancreatic beta-cell glucokinase: cDNA sequence and localization of the polymorphic gene to chromosome 7, band p 13. Diabetologia. 1992 Aug; 35(8):743-7. PMID: 1511800.
      Citations: 14     Fields:    Translation:HumansCells
    298. Drummond IA, Madden SL, Rohwer-Nutter P, Bell GI, Sukhatme VP, Rauscher FJ. Repression of the insulin-like growth factor II gene by the Wilms tumor suppressor WT1. Science. 1992 Jul 31; 257(5070):674-8. PMID: 1323141.
      Citations: 107     Fields:    Translation:HumansAnimalsCells
    299. Burant CF, Takeda J, Brot-Laroche E, Bell GI, Davidson NO. Fructose transporter in human spermatozoa and small intestine is GLUT5. J Biol Chem. 1992 Jul 25; 267(21):14523-6. PMID: 1634504.
      Citations: 150     Fields:    Translation:HumansAnimalsCells
    300. Rens-Domiano S, Law SF, Yamada Y, Seino S, Bell GI, Reisine T. Pharmacological properties of two cloned somatostatin receptors. Mol Pharmacol. 1992 Jul; 42(1):28-34. PMID: 1353250.
      Citations: 21     Fields:    Translation:AnimalsCells
    301. Raffel LJ, Hitman GA, Toyoda H, Karam JH, Bell GI, Rotter JI. The aggregation of the 5' insulin gene polymorphism in insulin dependent (type I) diabetes mellitus families. J Med Genet. 1992 Jul; 29(7):447-50. PMID: 1353534; PMCID: PMC1016016.
      Citations: 2     Fields:    Translation:Humans
    302. Liu ML, Olson AL, Moye-Rowley WS, Buse JB, Bell GI, Pessin JE. Expression and regulation of the human GLUT4/muscle-fat facilitative glucose transporter gene in transgenic mice. J Biol Chem. 1992 Jun 15; 267(17):11673-6. PMID: 1601840.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    303. Vionnet N, Stoffel M, Takeda J, Yasuda K, Bell GI, Zouali H, Lesage S, Velho G, Iris F, Passa P, et al. Nonsense mutation in the glucokinase gene causes early-onset non-insulin-dependent diabetes mellitus. Nature. 1992 Apr 23; 356(6371):721-2. PMID: 1570017.
      Citations: 158     Fields:    Translation:HumansCells
    304. Cox NJ, Xiang KS, Fajans SS, Bell GI. Mapping diabetes-susceptibility genes. Lessons learned from search for DNA marker for maturity-onset diabetes of the young. Diabetes. 1992 Apr; 41(4):401-7. PMID: 1607066.
      Citations: 5     Fields:    Translation:Humans
    305. Stoffel M, Bell GI. Microsatellite polymorphism in the human platelet glycoprotein IIIa gene (GP3A) on chromosome 17. Nucleic Acids Res. 1992 Mar 11; 20(5):1172. PMID: 1549507; PMCID: PMC312150.
      Citations: 1     Fields:    Translation:HumansCells
    306. Fajans SS, Bell GI, Bowden DW. MODY: a model for the study of the molecular genetics of NIDDM. J Lab Clin Med. 1992 Mar; 119(3):206-10. PMID: 1541870.
      Citations: 5     Fields:    Translation:Humans
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