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Evolved Cas9 variants with broad PAM compatibility and high DNA specificity.
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Evolved Cas9 variants with broad PAM compatibility and high DNA specificity.
Evolved Cas9 variants with broad PAM compatibility and high DNA specificity. Nature. 2018 04 05; 556(7699):57-63.
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PubMed
subject areas
CRISPR-Associated Proteins
CRISPR-Cas Systems
Deoxyribonucleases
Directed Molecular Evolution
DNA
DNA Cleavage
Gene Editing
Genome, Human
HEK293 Cells
Humans
Mutation
Nucleotide Motifs
Streptococcus pyogenes
Substrate Specificity
Transcriptional Activation
authors with profiles
Weixin Tang