The iron-containing domain is essential in Rad3 helicases for coupling of ATP hydrolysis to DNA translocation and for targeting the helicase to the single-stranded DNA-double-stranded DNA junction.

The iron-containing domain is essential in Rad3 helicases for coupling of ATP hydrolysis to DNA translocation and for targeting the helicase to the single-stranded DNA-double-stranded DNA junction. J Biol Chem. 2008 Jan 18; 283(3):1732-1743.

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subject areas

Adenosine Triphosphatases
Adenosine Triphosphate
Amino Acid Substitution
Archaea
Archaeal Proteins
Biological Transport
DNA Helicases
DNA Replication
DNA, Cruciform
DNA, Single-Stranded
Hydrolysis
Iron-Sulfur Proteins
Ligands
Mutant Proteins
Mutation
Protein Binding
Protein Structure, Tertiary
Structure-Activity Relationship
Substrate Specificity
Thermodynamics

authors with profiles

Alvin Thomas