"Clusterin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A highly conserved heterodimeric glycoprotein that is differentially expressed during many severe physiological disturbance states such as CANCER; APOPTOSIS; and various NEUROLOGICAL DISORDERS. Clusterin is ubiquitously expressed and appears to function as a secreted MOLECULAR CHAPERONE.
| Descriptor ID |
D051152
|
| MeSH Number(s) |
D12.776.395.207 D12.776.580.215
|
| Concept/Terms |
Clusterin- Clusterin
- SGP-2 Protein
- SGP 2 Protein
- Apolipoprotein J
- Complement Lysis Inhibitor
- Complement-Associated Protein SP-40,40
- Complement Associated Protein SP 40,40
- SP-40,40, Complement-Associated Protein
- Sulfated Glycoprotein 2
- Sulfated Glycoprotein-2
- Ionizing Radiation-Induced Protein-8
- Ionizing Radiation Induced Protein 8
- Radiation-Induced Protein-8, Ionizing
- XIP8 Protein
- X-Ray-Inducible Protein 8
- X Ray Inducible Protein 8
- Testosterone-Repressed Prostate Message-2 Protein
- Testosterone Repressed Prostate Message 2 Protein
- ApoJ Protein
- TRPM-2 Protein
- TRPM 2 Protein
- MAC393 Antigen
- SP 40,40 Protein
|
Below are MeSH descriptors whose meaning is more general than "Clusterin".
Below are MeSH descriptors whose meaning is more specific than "Clusterin".
This graph shows the total number of publications written about "Clusterin" by people in this website by year, and whether "Clusterin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Clusterin" by people in Profiles.
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Characterization of primary cultures of adult human epididymis epithelial cells. Fertil Steril. 2015 Mar; 103(3):647-54.e1.
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Influenza A virus nucleoprotein induces apoptosis in human airway epithelial cells: implications of a novel interaction between nucleoprotein and host protein Clusterin. Cell Death Dis. 2013 Mar 28; 4:e562.
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HDL apolipoprotein-related peptides in the treatment of atherosclerosis and other inflammatory disorders. Curr Pharm Des. 2010; 16(28):3173-84.
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Increased clusterin expression in Fuchs' endothelial dystrophy. Invest Ophthalmol Vis Sci. 2008 Jul; 49(7):2946-55.
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NF-kappaB-dependent genes induced by proteinuria and identified using DNA microarrays. Clin Exp Nephrol. 2008 Jun; 12(3):181-8.
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Inhibition of NF-kappaB-dependent Bcl-xL expression by clusterin promotes albumin-induced tubular cell apoptosis. Kidney Int. 2008 Mar; 73(5):567-77.
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Isolation and characterization of a novel gene CLUAP1 whose expression is frequently upregulated in colon cancer. Oncogene. 2004 Dec 09; 23(57):9289-94.
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Apolipoprotein E receptors mediate the effects of beta-amyloid on astrocyte cultures. J Biol Chem. 2000 Oct 27; 275(43):33974-80.
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Lipoproteins in the central nervous system. Ann N Y Acad Sci. 2000 Apr; 903:167-75.
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Adhesion-induced differentiation of oligodendrocytes signals the synthesis and polarization of heparan sulfate proteoglycans and sulfated glycoproteins. Ann N Y Acad Sci. 1991; 633:530-4.