"Osteonectin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Non-collagenous, calcium-binding glycoprotein of developing bone. It links collagen to mineral in the bone matrix. In the synonym SPARC glycoprotein, the acronym stands for Secreted Protein, Acidic and Rich in Cysteine.
| Descriptor ID |
D015676
|
| MeSH Number(s) |
D12.776.157.125.715 D12.776.395.600
|
| Concept/Terms |
Osteonectin- Osteonectin
- SPARC Glycoprotein
- BM-40
- Basement Membrane Tumor Protein
- BM 40 Protein
|
Below are MeSH descriptors whose meaning is more general than "Osteonectin".
Below are MeSH descriptors whose meaning is more specific than "Osteonectin".
This graph shows the total number of publications written about "Osteonectin" by people in this website by year, and whether "Osteonectin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 2 | 0 | 2 |
| 2011 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 1 | 2 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Osteonectin" by people in Profiles.
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The Development and Initial Findings of A Study of a Prospective Adult Research Cohort with Inflammatory Bowel Disease (SPARC IBD). Inflamm Bowel Dis. 2022 02 01; 28(2):192-199.
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Stem cell-like transcriptional reprogramming mediates metastatic resistance to mTOR inhibition. Oncogene. 2017 05 11; 36(19):2737-2749.
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Secreted protein acidic and rich in cysteine (SPARC) induces lipotoxicity in neuroblastoma by regulating transport of albumin complexed with fatty acids. Oncotarget. 2016 Nov 22; 7(47):77696-77706.
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Dynamic regulation of basement membrane protein levels promotes egg chamber elongation in Drosophila. Dev Biol. 2015 Oct 15; 406(2):212-21.
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SPARC promotes leukemic cell growth and predicts acute myeloid leukemia outcome. J Clin Invest. 2014 Apr; 124(4):1512-24.
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Spontaneous osteoblastic osteosarcoma in a Mongolian gerbil (Meriones unguiculatus). Comp Med. 2013 Feb; 63(1):62-6.
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Secreted protein acidic and rich in cysteine is a matrix scavenger chaperone. PLoS One. 2011; 6(9):e23880.
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Identification of SPARC as a candidate target antigen for immunotherapy of various cancers. Int J Cancer. 2010 Sep 01; 127(6):1393-403.
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Anti-angiogenic SPARC peptides inhibit progression of neuroblastoma tumors. Mol Cancer. 2010 Jun 04; 9:138.
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Modulation of matrix remodeling by SPARC in neoplastic progression. Semin Cell Dev Biol. 2010 Feb; 21(1):55-65.