Protein Tyrosine Phosphatase, Non-Receptor Type 1
"Protein Tyrosine Phosphatase, Non-Receptor Type 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subtype of non-receptor protein tyrosine phosphatases that includes two distinctive targeting motifs; an N-terminal motif specific for the INSULIN RECEPTOR, and a C-terminal motif specific for the SH3 domain containing proteins. This subtype includes a hydrophobic domain which localizes it to the ENDOPLASMIC RETICULUM.
| Descriptor ID |
D054562
|
| MeSH Number(s) |
D08.811.277.352.650.775.300.100 D12.644.360.585.100 D12.776.476.564.100
|
| Concept/Terms |
Protein Tyrosine Phosphatase, Non-Receptor Type 1- Protein Tyrosine Phosphatase, Non-Receptor Type 1
- Protein Tyrosine Phosphatase, Non Receptor Type 1
- PTPase HA2
- Protein Tyrosine Phosphatase 1B
- PTPase 1B
- Protein-Tyrosine Phosphatase HA2
- Protein Tyrosine Phosphatase HA2
|
Below are MeSH descriptors whose meaning is more general than "Protein Tyrosine Phosphatase, Non-Receptor Type 1".
Below are MeSH descriptors whose meaning is more specific than "Protein Tyrosine Phosphatase, Non-Receptor Type 1".
This graph shows the total number of publications written about "Protein Tyrosine Phosphatase, Non-Receptor Type 1" by people in this website by year, and whether "Protein Tyrosine Phosphatase, Non-Receptor Type 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Protein Tyrosine Phosphatase, Non-Receptor Type 1" by people in Profiles.
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PTPN2 copper-sensing relays copper level fluctuations into EGFR/CREB activation and associated CTR1 transcriptional repression. Nat Commun. 2024 Aug 13; 15(1):6947.
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PTPN1 Deficiency Modulates BMPR2 Signaling and Induces Endothelial Dysfunction in Pulmonary Arterial Hypertension. Cells. 2023 01 14; 12(2).
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Kinetic characterization of the inhibition of protein tyrosine phosphatase-1B by Vanadyl (VO2+) chelates. J Biol Inorg Chem. 2017 Dec; 22(8):1267-1279.
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Protein-Tyrosine Phosphatase-1B Mediates Sleep Fragmentation-Induced Insulin Resistance and Visceral Adipose Tissue Inflammation in Mice. Sleep. 2017 09 01; 40(9).
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Chronic sleep fragmentation during the sleep period induces hypothalamic endoplasmic reticulum stress and PTP1b-mediated leptin resistance in male mice. Sleep. 2015 Jan 01; 38(1):31-40.
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Liver-derived DEC205+B220+CD19- dendritic cells regulate T cell responses. J Immunol. 2001 Jun 15; 166(12):7042-52.