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Ryan Boudreau

TitleAssistant Professor
InstitutionUniversity of Chicago
DepartmentSurgery-Trauma and Acute Care
AddressChicago IL 60637
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Nordham KD, Tatum D, Patel MB, Paramesh A, Gragert L, Hossain MS, Duchesne JC, Nahmias J, Keeley JA, Himmler AN, Konstantopoulos A, Narisma R, Maiga AW, Peetz AB, Woodward B, Serrano J, Udekwu PO, Stiles A, Shell C, Eagleton A, Murry J, Pero B, Iacullo E, McLafferty B, Coonan E, Boudreau RM, Zimmerman SA, Shammassian BH, Harrell KN, Zhang J, Egodage T, Armento I, Morris P, Metheny J, Farrell MS, Painter MD, Taggart C, Spadafore P, Stodghill JD, Maghsoudi T, Jacobson LE, Williams JM, Sciarretta JD, Kim P, Hayton R, Gonzales D, Santos A, Bayouth CV, Vaughan J, Chowdhury SM, Ahmad F, Haan JM, Lightwine K, Marks JA, Rattigan D, Tabello D, Teicher E, Jacome TH, Davis G, Bernard AC, Smith B, Doles B, Morrissey SL, Patel N, Sawyer R, VandenBerg S, Marcos BS, West MA, Matsushima K, Park S, Lueckel SN, Hornor M, Dronzek V, Mentzer C, Mack TJ, Bugaev N, Abosena W, Alvarez C, Jean RJ, Hicks RC, Lieser MJ, McDonald H, Dumas RP, Fitzgerald CA, Terzian WTH, Tian Y, Mousafeiris V, Mulita F, Berne JD, Mederos DR, Palacio CH, Acosta MB, Garcia NM, Firnhaber J, Smith AA, Taghavi S. Hormone replacement before brain death increases organ donation rate after catastrophic brain injury: An EAST multicenter trial. J Trauma Acute Care Surg. 2026 Oct 01; 101(4):619-631. PMID: 42468021.
      Citations:    Fields:    
    2. Aldrich DJ, Boudreau RM, Cerasale M, Schram AW, Tang JW, Kostas T, Betancourt G, Terman E, Winters C, Xie TH, Gier N, Hu DA, Kalidoss S, Farnan JM, Arora VM, Martin SK. Development and implementation of a pre-clerkship value-added health systems science program: the value-added for inpatients by students and interdisciplinary teams consult service. Acad Med. 2026 04 01; 101(4):396-402. PMID: 41837661.
      Citations:    Fields:    Translation:Humans
    3. Stein CS, Zhang X, Witmer NH, Pennington ER, Hahn S, Straub AC, Shaikh SR, Boudreau RL. Mitoregulin supports mitochondrial membrane integrity and protects against cardiac ischaemia-reperfusion injury. Cardiovasc Res. 2026 03 26; 122(3):379-396. PMID: 41555203; PMCID: PMC13019689.
      Citations:    Fields:    Translation:AnimalsCells
    4. Clark CJ, Anderson CE, Dou A, Dierdorff JM, Galpin JD, Gissot L, Thompson SG, Choi H, Yoon JY, Infield DT, McLendon JM, Hoeger JM, Rabab'h O, Bronk P, Leeds K, Kutschke WJ, Paradee WJ, Boudreau RL, Choi BR, London B, Ahern CA. Sodium Channel Isoform Diversity Underlies Chamber-Specific Cardiac Excitability. Circ Res. 2026 Apr 24; 138(9):e328159. PMID: 41878815; PMCID: PMC13045664.
      Citations:    Fields:    Translation:AnimalsCells
    5. Witmer NH, Hoeger JM, McLendon JM, Stein CS, Yoon JY, Wang L, Berezhnaya E, Elrod JW, Knollmann BC, London B, Boudreau RL. Short SCN5A Transcript Yields a NaV1.5 Fragment Influencing Cardiac Metabolism. Circ Res. 2026 Apr 24; 138(9):e326973. PMID: 41808628; PMCID: PMC13045665.
      Citations:    Fields:    Translation:HumansAnimalsCells
    6. Katiki A, Rogers S, Boudreau R, Meltzer D, Prochaska M. Provider perceptions of indications for red blood cell transfusion. Transfusion. 2026 Feb; 66(2):326-333. PMID: 41427555; PMCID: PMC12902728.
      Citations: 1     Fields:    Translation:Humans
    7. Ismaeel A, Peck BD, Montgomery MM, Burke BI, Goh J, Franco AB, Xia Q, Goljanek-Whysall K, McDonagh B, McLendon JM, Koopmans PJ, Jacko D, Schaaf K, Bloch W, Gehlert S, Murach KA, Fisher-Wellman KH, Boudreau RL, Wen Y, McCarthy JJ. Corrigendum to "microRNA-1 regulates metabolic flexibility by programming skeletal muscle pyruvate metabolism" [Mol Metabol 98 (2025) 1-23/102182]. Mol Metab. 2025 Oct; 100:102223. PMID: 40774330; PMCID: PMC12356036.
      Citations:    Fields:    
    8. Qian L, Koval OM, Endoni BT, Juhr D, Stein CS, Allamargot C, Lin LH, Guo DF, Rahmouni K, Boudreau RL, Streeter J, Thiel WH, Grumbach IM. MIRO1 controls energy production and proliferation of vascular smooth muscle cells. bioRxiv. 2025 Jun 09. PMID: 39185180; PMCID: PMC11343164.
      Citations:    
    9. Ismaeel A, Peck BD, Montgomery MM, Burke BI, Goh J, Franco AB, Xia Q, Goljanek-Whysall K, McDonagh B, McLendon JM, Koopmans PJ, Jacko D, Schaaf K, Bloch W, Gehlert S, Murach KA, Fisher-Wellman KH, Boudreau RL, Wen Y, McCarthy JJ. microRNA-1 regulates metabolic flexibility by programming adult skeletal muscle pyruvate metabolism. Mol Metab. 2025 Aug; 98:102182. PMID: 40490136; PMCID: PMC12214129.
      Citations: 1     Fields:    Translation:HumansAnimals
    10. Nordham KD, Tatum D, Attia AS, Patel MB, Paramesh A, Duchesne JC, Nahmias J, Maiga AW, Peetz AB, Udekwu PO, Stiles A, Shell C, Stodghill JD, Maghsoudi T, Iacullo E, McLafferty B, Coonan E, Boudreau RM, Zimmerman SA, Shammassian B, Egodage T, Aramento I, Morris P, Metheny J, Farrell MS, Painter MD, McCabe OT, Spadafore P, Wong DT, Serrano J, Sciarretta JD, Kim P, Hayton R, Gonzales D, Murry J, Meadows K, Jacobson LE, Williams JM, Bernard AC, Smith B, Morrissey SL, Patel N, Tabello D, Teicher E, Chowdhury SM, Ahmad F, Marcos BS, West MA, Jacome TH, Davis G, Marks JA, Rattigan D, Haan JM, Lightwine K, Matsushima K, Park S, Santos A, Shrestha K, Sawyer R, VandenBerg S, Jean RJ, Hicks RC, Lueckel S, Bugaev N, Abosena W, Alvarez C, Lieser MJ, McDonald H, Dumas RP, Fitzgerald CA, Terzian WTH, Tian Y, Mousafeiris V, Mulita F, Berne JD, Mederos DR, Smith AA, Taghavi S. Impact of catastrophic brain injury guidelines on organ donation rates: Results of an EAST multicenter trial. J Trauma Acute Care Surg. 2025 01 01; 98(1):117-126. PMID: 39327646.
      Citations: 1     Fields:    Translation:Humans
    11. Ismaeel A, Peck BD, Montgomery MM, Burke BI, Goh J, Kang G, Franco AB, Xia Q, Goljanek-Whysall K, McDonagh B, McLendon JM, Koopmans PJ, Jacko D, Schaaf K, Bloch W, Gehlert S, Wen Y, Murach KA, Peterson CA, Boudreau RL, Fisher-Wellman KH, McCarthy JJ. microRNA-1 Regulates Metabolic Flexibility in Skeletal Muscle via Pyruvate Metabolism. bioRxiv. 2024 Aug 10. PMID: 39149347; PMCID: PMC11326265.
      Citations:    
    12. McLendon JM, Zhang X, Matasic DS, Kumar M, Koval OM, Grumbach IM, Sadayappan S, London B, Boudreau RL. Knockout of Sorbin And SH3 Domain Containing 2 (Sorbs2) in Cardiomyocytes Leads to Dilated Cardiomyopathy in Mice. J Am Heart Assoc. 2022 07 05; 11(13):e025687. PMID: 35730644; PMCID: PMC9333371.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    13. Saad NY, Al-Kharsan M, Garwick-Coppens SE, Chermahini GA, Harper MA, Palo A, Boudreau RL, Harper SQ. Human miRNA miR-675 inhibits DUX4 expression and may be exploited as a potential treatment for Facioscapulohumeral muscular dystrophy. Nat Commun. 2021 12 08; 12(1):7128. PMID: 34880230; PMCID: PMC8654987.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    14. Wang Y, Chen B, Huang CK, Guo A, Wu J, Zhang X, Chen R, Chen C, Kutschke W, Weiss RM, Boudreau RL, Margulies KB, Hong J, Song LS. Targeting Calpain for Heart Failure Therapy: Implications From Multiple Murine Models. JACC Basic Transl Sci. 2018 Aug; 3(4):503-517. PMID: 30175274; PMCID: PMC6115647.
      Citations: 39     
    15. Matkovich SJ, Boudreau RL. When Knowing "Enough" May Still Not Be Enough. Circ Res. 2018 08 03; 123(4):412-414. PMID: 30355252.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    16. Stein CS, Jadiya P, Zhang X, McLendon JM, Abouassaly GM, Witmer NH, Anderson EJ, Elrod JW, Boudreau RL. Mitoregulin: A lncRNA-Encoded Microprotein that Supports Mitochondrial Supercomplexes and Respiratory Efficiency. Cell Rep. 2018 06 26; 23(13):3710-3720.e8. PMID: 29949756; PMCID: PMC6091870.
      Citations: 153     Fields:    Translation:HumansAnimalsCells
    17. Zhang X, Yoon JY, Morley M, McLendon JM, Mapuskar KA, Gutmann R, Mehdi H, Bloom HL, Dudley SC, Ellinor PT, Shalaby AA, Weiss R, Tang WHW, Moravec CS, Singh M, Taylor AL, Yancy CW, Feldman AM, McNamara DM, Irani K, Spitz DR, Breheny P, Margulies KB, London B, Boudreau RL. A common variant alters SCN5A-miR-24 interaction and associates with heart failure mortality. J Clin Invest. 2018 03 01; 128(3):1154-1163. PMID: 29457789; PMCID: PMC5824852.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    18. Liu W, Deng J, Ding W, Wang G, Shen Y, Zheng J, Zhang X, Luo Y, Lv C, Wang Y, Chen L, Yan D, Boudreau RL, Song LS, Liu J. Decreased KCNE2 Expression Participates in the Development of Cardiac Hypertrophy by Regulation of Calcineurin-NFAT (Nuclear Factor of Activated T Cells) and Mitogen-Activated Protein Kinase Pathways. Circ Heart Fail. 2017 Jun; 10(6). PMID: 28611128.
      Citations: 2     Fields:    Translation:HumansAnimals
    19. Vikram A, Lewarchik CM, Yoon JY, Naqvi A, Kumar S, Morgan GM, Jacobs JS, Li Q, Kim YR, Kassan M, Liu J, Gabani M, Kumar A, Mehdi H, Zhu X, Guan X, Kutschke W, Zhang X, Boudreau RL, Dai S, Matasic DS, Jung SB, Margulies KB, Kumar V, Bachschmid MM, London B, Irani K. Sirtuin 1 regulates cardiac electrical activity by deacetylating the cardiac sodium channel. Nat Med. 2017 Mar; 23(3):361-367. PMID: 28191886; PMCID: PMC6218171.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    20. Kim YC, Miller A, Lins LC, Han SW, Keiser MS, Boudreau RL, Davidson BL, Narayanan NS. RNA Interference of Human a-Synuclein in Mouse. Front Neurol. 2017; 8:13. PMID: 28197125; PMCID: PMC5281542.
      Citations: 16     
    21. Spengler RM, Zhang X, Cheng C, McLendon JM, Skeie JM, Johnson FL, Davidson BL, Boudreau RL. Elucidation of transcriptome-wide microRNA binding sites in human cardiac tissues by Ago2 HITS-CLIP. Nucleic Acids Res. 2016 09 06; 44(15):7120-31. PMID: 27418678; PMCID: PMC5009757.
      Citations: 45     Fields:    Translation:HumansCells
    22. Ramachandran PS, Boudreau RL, Schaefer KA, La Spada AR, Davidson BL. Nonallele specific silencing of ataxin-7 improves disease phenotypes in a mouse model of SCA7. Mol Ther. 2014 Sep; 22(9):1635-42. PMID: 24930601; PMCID: PMC4435484.
      Citations: 34     Fields:    Translation:AnimalsCells
    23. Ramachandran PS, Bhattarai S, Singh P, Boudreau RL, Thompson S, Laspada AR, Drack AV, Davidson BL. RNA interference-based therapy for spinocerebellar ataxia type 7 retinal degeneration. PLoS One. 2014; 9(4):e95362. PMID: 24759684; PMCID: PMC3997397.
      Citations: 19     Fields:    Translation:HumansAnimals
    24. Boudreau RL, Jiang P, Gilmore BL, Spengler RM, Tirabassi R, Nelson JA, Ross CA, Xing Y, Davidson BL. Transcriptome-wide discovery of microRNA binding sites in human brain. Neuron. 2014 Jan 22; 81(2):294-305. PMID: 24389009; PMCID: PMC4108341.
      Citations: 136     Fields:    Translation:HumansAnimalsCells
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