"Cell Dedifferentiation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A reverse developmental process in which terminally differentiated cells with specialized functions revert back to a less differentiated stage within their own CELL LINEAGE.
| Descriptor ID |
D054337
|
| MeSH Number(s) |
G04.148
|
| Concept/Terms |
Cell Dedifferentiation- Cell Dedifferentiation
- Cell Dedifferentiations
- Dedifferentiations, Cell
- Dedifferentiation, Cell
|
Below are MeSH descriptors whose meaning is more general than "Cell Dedifferentiation".
Below are MeSH descriptors whose meaning is more specific than "Cell Dedifferentiation".
This graph shows the total number of publications written about "Cell Dedifferentiation" by people in this website by year, and whether "Cell Dedifferentiation" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 1 | 2 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cell Dedifferentiation" by people in Profiles.
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Increased Anaplastic Lymphoma Kinase Activity Induces a Poorly Differentiated Thyroid Carcinoma in Mice. Thyroid. 2019 10; 29(10):1438-1446.
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Histone deacetylase inhibitor-induced cancer stem cells exhibit high pentose phosphate pathway metabolism. Oncotarget. 2016 May 10; 7(19):28329-39.
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ß-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment. J Clin Endocrinol Metab. 2014 Jun; 99(6):1983-92.
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BRAF mutation in 'sarcomas': a possible method to detect de-differentiated melanomas. Histopathology. 2014 Apr; 64(5):639-46.
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Modulation of PKC-a promotes lineage reprogramming of committed B lymphocytes. Eur J Immunol. 2012 Apr; 42(4):1005-15.
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A general method to derive robust organ-specific gene expression-based differentiation indices: application to thyroid cancer diagnostic. Oncogene. 2012 Oct 11; 31(41):4490-8.