"Clonal Evolution" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process of accumulation of genetic and epigenetic changes over time in individual cells and the effect of the changes on CELL PROLIFERATION.
| Descriptor ID |
D060965
|
| MeSH Number(s) |
G04.375 G05.158
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Clonal Evolution".
Below are MeSH descriptors whose meaning is more specific than "Clonal Evolution".
This graph shows the total number of publications written about "Clonal Evolution" by people in this website by year, and whether "Clonal Evolution" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 0 | 2 | 2 |
| 2014 | 1 | 0 | 1 |
| 2017 | 0 | 2 | 2 |
| 2020 | 1 | 1 | 2 |
| 2021 | 3 | 0 | 3 |
| 2023 | 2 | 0 | 2 |
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Below are the most recent publications written about "Clonal Evolution" by people in Profiles.
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Blast Phase of Myeloproliferative Neoplasm Resembles Acute Myeloid Leukemia, Myelodysplasia-Related, in Clinical Presentation, Cytogenetic Pattern, and Genomic Profile, and Often Undergoes Reversion to Second Chronic Phase Status After Induction Chemotherapy. Arch Pathol Lab Med. 2024 Dec 01; 148(12):1310-1319.
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Mutations observed in somatic evolution reveal underlying gene mechanisms. Commun Biol. 2023 07 19; 6(1):753.
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Chronic Lymphocytic Leukemia With Two B-Cell Populations of Discordant Light Chain Restrictions in Individual Patients: Parallel Development of Biclonal B-Cell Neoplasms or Clonal Evolution With Isotype Switch? Am J Clin Pathol. 2023 04 04; 159(4):337-351.
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Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes. Nat Commun. 2021 11 26; 12(1):6946.
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Clonal evolution of acute myeloid leukemia with FLT3-ITD mutation under treatment with midostaurin. Blood. 2021 06 03; 137(22):3093-3104.
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Genomic analysis of cellular hierarchy in acute myeloid leukemia using ultrasensitive LC-FACSeq. Leukemia. 2021 12; 35(12):3406-3420.
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Genomics of MPN progression. Hematology Am Soc Hematol Educ Program. 2020 12 04; 2020(1):440-449.
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LC-FACSeq is a method for detecting rare clones in leukemia. JCI Insight. 2020 06 18; 5(12).
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Genomic determinants of chronic myelomonocytic leukemia. Leukemia. 2017 12; 31(12):2815-2823.
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KRAS Allelic Imbalance Enhances Fitness and Modulates MAP Kinase Dependence in Cancer. Cell. 2017 02 23; 168(5):817-829.e15.