Cell Transdifferentiation
"Cell Transdifferentiation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A naturally occurring phenomenon where terminally differentiated cells dedifferentiate to the point where they can switch CELL LINEAGES. The cells then differentiate into other cell types.
Descriptor ID |
D054338
|
MeSH Number(s) |
G04.356
|
Concept/Terms |
Cell Transdifferentiation- Cell Transdifferentiation
- Cell Transdifferentiations
- Transdifferentiations, Cell
- Transdifferentiation, Cell
|
Below are MeSH descriptors whose meaning is more general than "Cell Transdifferentiation".
Below are MeSH descriptors whose meaning is more specific than "Cell Transdifferentiation".
This graph shows the total number of publications written about "Cell Transdifferentiation" by people in this website by year, and whether "Cell Transdifferentiation" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2008 | 1 | 1 | 2 |
2012 | 1 | 2 | 3 |
2014 | 0 | 1 | 1 |
2015 | 0 | 1 | 1 |
2016 | 2 | 1 | 3 |
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Below are the most recent publications written about "Cell Transdifferentiation" by people in Profiles.
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MiR-590 Promotes Transdifferentiation of Porcine and Human Fibroblasts Toward a Cardiomyocyte-Like Fate by Directly Repressing Specificity Protein 1. J Am Heart Assoc. 2016 11 10; 5(11).
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In situ reprogramming to transdifferentiate fibroblasts into cardiomyocytes using adenoviral vectors: Implications for clinical myocardial regeneration. J Thorac Cardiovasc Surg. 2017 02; 153(2):329-339.e3.
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Less may be more: Using small molecules to reprogram human cells into functional cardiomyocytes. J Thorac Cardiovasc Surg. 2017 01; 153(1):128-130.
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Glucagon is essential for alpha cell transdifferentiation and beta cell neogenesis. Development. 2015 Apr 15; 142(8):1407-17.
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Knockdown of Hnrnpa0, a del(5q) gene, alters myeloid cell fate in murine cells through regulation of AU-rich transcripts. Haematologica. 2014 Jun; 99(6):1032-40.
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Deficiency in metabolic regulators PPAR? and PTEN cooperates to drive keratinizing squamous metaplasia in novel models of human tissue regeneration. Am J Pathol. 2013 Feb; 182(2):449-59.
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Molecular basis of cardiac endothelial-to-mesenchymal transition (EndMT): differential expression of microRNAs during EndMT. Cell Signal. 2012 May; 24(5):1031-6.
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Analysis of the endocardial-to-mesenchymal transformation of heart valve development by collagen gel culture assay. Methods Mol Biol. 2012; 843:101-9.
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Urothelial transdifferentiation to prostate epithelia is mediated by paracrine TGF-beta signaling. Differentiation. 2009 Jan; 77(1):95-102.
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Clonally related follicular lymphomas and histiocytic/dendritic cell sarcomas: evidence for transdifferentiation of the follicular lymphoma clone. Blood. 2008 Jun 15; 111(12):5433-9.