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EGR2 induces apoptosis in various cancer cell lines by direct transactivation of BNIP3L and BAK.
Treatment of brain metastases.
Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture.
Pleiotropic genes for metabolic syndrome and inflammation.
Multimodal interaction with BCL-2 family proteins underlies the proapoptotic activity of PUMA BH3.
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Multimodal interaction with BCL-2 family proteins underlies the proapoptotic activity of PUMA BH3.
Multimodal interaction with BCL-2 family proteins underlies the proapoptotic activity of PUMA BH3. Chem Biol. 2013 Jul 25; 20(7):888-902.
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PubMed
subject areas
Amino Acid Sequence
Animals
Apoptosis
Apoptosis Regulatory Proteins
bcl-2-Associated X Protein
Caspase 3
Caspase 7
Enzyme Activation
HEK293 Cells
Humans
Mice
Models, Molecular
Molecular Sequence Data
Porosity
Protein Structure, Tertiary
Proteomics
Proto-Oncogene Proteins c-bcl-2
Substrate Specificity
authors with profiles
James L. LaBelle