Autophagy-Related Protein 7
"Autophagy-Related Protein 7" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An autophagy related protein that is similar to UBIQUITIN-ACTIVATING ENZYME E1. It functions in CYTOPLASM to VACUOLE transport (Cvt) and AUTOPHAGY by activating ATG12 PROTEIN for its conjugation with ATG5 PROTEIN, as well as the conjugation of ATG8 FAMILY PROTEINS with phosphatidylethanolamine for ATG8 association to Cvt vesicles and AUTOPHAGOSOME membranes. It is also required for the nitrogen starvation response in yeast, MITOPHAGY; and autophagic cell death induced by CASPASE 8 inhibition.
| Descriptor ID |
D000071193
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| MeSH Number(s) |
D12.776.094.399
|
| Concept/Terms |
Autophagy-Related Protein 7- Autophagy-Related Protein 7
- Autophagy Related Protein 7
- ATG7 Protein
- Ubiquitin-Activating Enzyme E1-like Protein
- Ubiquitin Activating Enzyme E1 like Protein
- Ubiquitin-Like Modifier-Activating Enzyme ATG7
- Ubiquitin Like Modifier Activating Enzyme ATG7
- ATG12-Activating Enzyme E1 ATG7
- ATG12 Activating Enzyme E1 ATG7
|
Below are MeSH descriptors whose meaning is more general than "Autophagy-Related Protein 7".
Below are MeSH descriptors whose meaning is more specific than "Autophagy-Related Protein 7".
This graph shows the total number of publications written about "Autophagy-Related Protein 7" by people in this website by year, and whether "Autophagy-Related Protein 7" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 1 | 2 |
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Below are the most recent publications written about "Autophagy-Related Protein 7" by people in Profiles.
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Inhibition of p70 S6 kinase activity by A77 1726 induces autophagy and enhances the degradation of superoxide dismutase 1 (SOD1) protein aggregates. Cell Death Dis. 2018 03 14; 9(3):407.
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Astrocytes promote progression of breast cancer metastases to the brain via a KISS1-mediated autophagy. Autophagy. 2017; 13(11):1905-1923.
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Visceral White Adipose Tissue after Chronic Intermittent and Sustained Hypoxia in Mice. Am J Respir Cell Mol Biol. 2017 04; 56(4):477-487.
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Autophagy gene ATG7 regulates ultraviolet radiation-induced inflammation and skin tumorigenesis. Autophagy. 2017; 13(12):2086-2103.
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Soluble bioactive microbial mediators regulate proteasomal degradation and autophagy to protect against inflammation-induced stress. Am J Physiol Gastrointest Liver Physiol. 2016 10 01; 311(4):G634-G647.
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Altered autophagic flux enhances inflammatory responses during inflammation-induced preterm labor. Sci Rep. 2015 Mar 23; 5:9410.
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The parasitophorous vacuole membrane of Toxoplasma gondii is targeted for disruption by ubiquitin-like conjugation systems of autophagy. Immunity. 2014 Jun 19; 40(6):924-35.
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p62/SQSTM1 accumulation in squamous cell carcinoma of head and neck predicts sensitivity to phosphatidylinositol 3-kinase pathway inhibitors. PLoS One. 2014; 9(3):e90171.
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Autophagy is a critical mechanism for the induction of the antileukemic effects of arsenic trioxide. J Biol Chem. 2010 Sep 24; 285(39):29989-97.