PAX3 Transcription Factor
"PAX3 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A paired box transcription factor that functions in CELL PROLIFERATION; CELL MIGRATION; and APOPTOSIS. It also is involved in MYOGENESIS and neural development. Mutations in the PAX3 gene are associated with WAARDENBURG SYNDROME TYPE 1.
| Descriptor ID |
D000072041
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| MeSH Number(s) |
D12.776.260.645.782 D12.776.930.700.782
|
| Concept/Terms |
PAX3 Transcription Factor- PAX3 Transcription Factor
- Transcription Factor, PAX3
- Paired Box Transcription Factor 3
- Transcription Factor PAX3
- Factor PAX3, Transcription
- PAX3, Transcription Factor
- Paired Box 3 Protein
|
Below are MeSH descriptors whose meaning is more general than "PAX3 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "PAX3 Transcription Factor".
This graph shows the total number of publications written about "PAX3 Transcription Factor" by people in this website by year, and whether "PAX3 Transcription Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 2 | 2 |
| 2015 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "PAX3 Transcription Factor" by people in Profiles.
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Functional analysis of a SOX10 gene mutation associated with Waardenburg syndrome II. Biochem Biophys Res Commun. 2017 11 04; 493(1):258-262.
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FOXD3 Promotes PAX3 Expression in Melanoma Cells. J Cell Biochem. 2016 Feb; 117(2):533-41.
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PAX3 and FOXD3 Promote CXCR4 Expression in Melanoma. J Biol Chem. 2015 Sep 04; 290(36):21901-14.
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PAX3 and ETS1 synergistically activate MET expression in melanoma cells. Oncogene. 2015 Sep 17; 34(38):4964-74.
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GSK-3 promotes cell survival, growth, and PAX3 levels in human melanoma cells. Mol Cancer Res. 2012 Aug; 10(8):1065-76.
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Conditional immortalization establishes a repertoire of mouse melanocyte progenitors with distinct melanogenic differentiation potential. J Invest Dermatol. 2012 Oct; 132(10):2479-2483.
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Emerin inhibits Lmo7 binding to the Pax3 and MyoD promoters and expression of myoblast proliferation genes. J Cell Sci. 2011 May 15; 124(Pt 10):1691-702.
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PAX3 and SOX10 activate MET receptor expression in melanoma. Pigment Cell Melanoma Res. 2010 Apr; 23(2):225-37.
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Pigmentation PAX-ways: the role of Pax3 in melanogenesis, melanocyte stem cell maintenance, and disease. Pigment Cell Melanoma Res. 2008 Dec; 21(6):627-45.
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PAX3 expression in primary melanomas and nevi. Mod Pathol. 2008 May; 21(5):525-30.