Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein
"Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A caspase-like cysteine endopeptidase that also exhibits ubiquitin ligase activity. It contains an N-terminal DEATH DOMAIN, two IMMUNOGLOBULIN-LIKE DOMAINS, and localizes to the perinuclear region of MONOCYTES, where it functions in activation of NF-KAPPA B; it also binds to and activates TRAF6. Chromosomal translocations involving the MALT1 and BIRC2 genes are associated with MALT LYMPHOMA, and mutations in the MALT1 gene are associated with Type 12 IMMUNODEFICIENCY SYNDROMES.
Descriptor ID |
D000074884
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MeSH Number(s) |
D08.811.277.656.262.500.126.775 D08.811.277.656.300.200.126.775 D08.811.464.938.750.233
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein".
Below are MeSH descriptors whose meaning is more specific than "Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein".
This graph shows the total number of publications written about "Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein" by people in this website by year, and whether "Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2008 | 0 | 1 | 1 |
2009 | 0 | 1 | 1 |
2014 | 0 | 1 | 1 |
2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein" by people in Profiles.
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Cellular metabolism constrains innate immune responses in early human ontogeny. Nat Commun. 2018 11 16; 9(1):4822.
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Inhibiting CARD11 translation during BCR activation by targeting the eIF4A RNA helicase. Blood. 2014 Dec 11; 124(25):3758-67.
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Pharmacologic inhibition of MALT1 protease by phenothiazines as a therapeutic approach for the treatment of aggressive ABC-DLBCL. Cancer Cell. 2012 Dec 11; 22(6):825-37.
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From MALT lymphoma to the CBM signalosome: three decades of discovery. Cell Cycle. 2011 Aug 01; 10(15):2485-96.
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CARMA1 controls an early checkpoint in the thymic development of FoxP3+ regulatory T cells. J Immunol. 2009 Jun 01; 182(11):6736-43.
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Chromosomal aberrations in a case of synchronous extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue type and bronchogenic adenocarcinoma. Appl Immunohistochem Mol Morphol. 2008 May; 16(3):296-300.