Phosphoric Diester Hydrolases
"Phosphoric Diester Hydrolases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of enzymes that catalyze the hydrolysis of one of the two ester bonds in a phosphodiester compound. EC 3.1.4.
| Descriptor ID |
D010727
|
| MeSH Number(s) |
D08.811.277.352.640
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Phosphoric Diester Hydrolases".
Below are MeSH descriptors whose meaning is more specific than "Phosphoric Diester Hydrolases".
This graph shows the total number of publications written about "Phosphoric Diester Hydrolases" by people in this website by year, and whether "Phosphoric Diester Hydrolases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 0 | 1 | 1 |
| 2005 | 1 | 2 | 3 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2018 | 1 | 1 | 2 |
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Below are the most recent publications written about "Phosphoric Diester Hydrolases" by people in Profiles.
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Akt-mediated platelet apoptosis and its therapeutic implications in immune thrombocytopenia. Proc Natl Acad Sci U S A. 2018 11 06; 115(45):E10682-E10691.
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The Genetic Landscape of Cerebral Steno-Occlusive Arteriopathy and Stroke in Sickle Cell Anemia. J Stroke Cerebrovasc Dis. 2018 Nov; 27(11):2897-2904.
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Antithrombotic activities of ferulic acid via intracellular cyclic nucleotide signaling. Eur J Pharmacol. 2016 Apr 15; 777:1-8.
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Polyunsaturated lysophosphatidic acid as a potential asthma biomarker. Biomark Med. 2016; 10(2):123-35.
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Autotaxin production of lysophosphatidic acid mediates allergic asthmatic inflammation. Am J Respir Crit Care Med. 2013 Oct 15; 188(8):928-40.
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The polybasic insertion in autotaxin a confers specific binding to heparin and cell surface heparan sulfate proteoglycans. J Biol Chem. 2013 Jan 04; 288(1):510-9.
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Genome-wide association and functional follow-up reveals new loci for kidney function. PLoS Genet. 2012; 8(3):e1002584.
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Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans. Proc Natl Acad Sci U S A. 2012 Mar 06; 109(10):3985-90.
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Autotaxin induces lung epithelial cell migration through lysoPLD activity-dependent and -independent pathways. Biochem J. 2011 Oct 01; 439(1):45-55.
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Preclinical evaluation of 18F-JNJ41510417 as a radioligand for PET imaging of phosphodiesterase-10A in the brain. J Nucl Med. 2010 Oct; 51(10):1584-91.