Transforming Growth Factor beta3
"Transforming Growth Factor beta3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A TGF-beta subtype that plays role in regulating epithelial-mesenchymal interaction during embryonic development. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta3 and TGF-beta3 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor.
| Descriptor ID |
D053782
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| MeSH Number(s) |
D12.644.276.374.687.300 D12.644.276.954.775.300 D12.776.467.374.687.300 D12.776.467.942.775.300 D23.529.942.775.300
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Transforming Growth Factor beta3".
Below are MeSH descriptors whose meaning is more specific than "Transforming Growth Factor beta3".
This graph shows the total number of publications written about "Transforming Growth Factor beta3" by people in this website by year, and whether "Transforming Growth Factor beta3" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2008 | 0 | 2 | 2 |
| 2009 | 0 | 1 | 1 |
| 2011 | 1 | 1 | 2 |
| 2014 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2019 | 0 | 2 | 2 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Transforming Growth Factor beta3" by people in Profiles.
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Simvastatin inhibits stem cell proliferation in human leiomyoma via TGF-ß3 and Wnt/ß-Catenin pathways. J Cell Mol Med. 2022 03; 26(5):1684-1698.
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Targeting the transforming growth factor-ß pathway: a novel mechanism of ulipristal acetate action against uterine fibroids. Fertil Steril. 2019 04; 111(4):683-684.
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P311 Promotes Lung Fibrosis via Stimulation of Transforming Growth Factor-ß1, -ß2, and -ß3 Translation. Am J Respir Cell Mol Biol. 2019 02; 60(2):221-231.
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ATP-citrate lyase is essential for high glucose-induced histone hyperacetylation and fibrogenic gene upregulation in mesangial cells. Am J Physiol Renal Physiol. 2017 Aug 01; 313(2):F423-F429.
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Novel RNA-binding protein P311 binds eukaryotic translation initiation factor 3 subunit b (eIF3b) to promote translation of transforming growth factor ß1-3 (TGF-ß1-3). J Biol Chem. 2014 Dec 05; 289(49):33971-83.
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Directed differentiation of skin-derived precursors into functional vascular smooth muscle cells. Arterioscler Thromb Vasc Biol. 2011 Dec; 31(12):2938-48.
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1,25-Dihydroxyvitamin D3 reduces TGF-beta3-induced fibrosis-related gene expression in human uterine leiomyoma cells. J Clin Endocrinol Metab. 2011 Apr; 96(4):E754-62.
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Regeneration of the articular surface of the rabbit synovial joint by cell homing: a proof of concept study. Lancet. 2010 Aug 07; 376(9739):440-8.
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The role of regional posterior frontal dura mater in the overlying suture morphology. Plast Reconstr Surg. 2009 Feb; 123(2):463-469.
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Microarray analysis of the role of regional dura mater in cranial suture fate. Plast Reconstr Surg. 2008 Aug; 122(2):389-399.