Genistein inhibits proliferation of colon cancer cells by attenuating a negative effect of epidermal growth factor on tumor suppressor FOXO3 activity.

Genistein inhibits proliferation of colon cancer cells by attenuating a negative effect of epidermal growth factor on tumor suppressor FOXO3 activity. BMC Cancer. 2011 Jun 03; 11:219.

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subject areas

Antineoplastic Agents
Cell Line, Tumor
Cell Proliferation
Colonic Neoplasms
Cyclin-Dependent Kinase Inhibitor p27
Epidermal Growth Factor
Forkhead Box Protein O3
Forkhead Transcription Factors
Gene Expression Regulation, Neoplastic
Genistein
HCT116 Cells
HT29 Cells
Humans
Intracellular Space
Mutant Proteins
Phosphatidylinositol 3-Kinases
Phosphorylation
Promoter Regions, Genetic
Protein Binding
Protein Transport
Proto-Oncogene Proteins c-akt
Signal Transduction
Tumor Suppressor Protein p53

authors with profiles

Christopher Weber