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Ouabain inhibits placental sFlt1 production by repressing HSP27-dependent HIF-1a pathway.
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Ouabain inhibits placental sFlt1 production by repressing HSP27-dependent HIF-1a pathway.
Ouabain inhibits placental sFlt1 production by repressing HSP27-dependent HIF-1a pathway. FASEB J. 2014 Oct; 28(10):4324-34.
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PubMed
subject areas
Animals
Blood Pressure
Cardenolides
Cardiotonic Agents
Cells, Cultured
Digitoxin
Dose-Response Relationship, Drug
Female
HSP27 Heat-Shock Proteins
Humans
Hypertension, Pregnancy-Induced
Hypoxia-Inducible Factor 1, alpha Subunit
Ouabain
Phosphorylation
Placenta
Pregnancy
Rats
Rats, Sprague-Dawley
RNA, Messenger
Vascular Endothelial Growth Factor Receptor-1
authors with profiles
Sarosh Rana