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TiPARP forms nuclear condensates to degrade HIF-1a and suppress tumorigenesis.
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TiPARP forms nuclear condensates to degrade HIF-1a and suppress tumorigenesis.
TiPARP forms nuclear condensates to degrade HIF-1a and suppress tumorigenesis. Proc Natl Acad Sci U S A. 2020 06 16; 117(24):13447-13456.
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PubMed
subject areas
ADP-Ribosylation
Animals
Cell Line, Tumor
Cell Nucleus
Cell Transformation, Neoplastic
Estrogen Receptor alpha
Feedback, Physiological
Gene Expression Regulation, Neoplastic
Humans
Hypoxia-Inducible Factor 1, alpha Subunit
Mice
Nucleoside Transport Proteins
Poly(ADP-ribose) Polymerases
Protein Interaction Domains and Motifs
Proto-Oncogene Proteins c-myc
Tumor Suppressor Proteins
Ubiquitination
Ubiquitin-Protein Ligases
authors with profiles
Hening Lin