CHK1 and WEE1 inhibition combine synergistically to enhance therapeutic efficacy in acute myeloid leukemia ex vivo.

CHK1 and WEE1 inhibition combine synergistically to enhance therapeutic efficacy in acute myeloid leukemia ex vivo. Haematologica. 2014 Apr; 99(4):688-96.

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subject areas

Apoptosis
Ataxia Telangiectasia Mutated Proteins
Cell Cycle Proteins
Cell Line, Tumor
Checkpoint Kinase 1
Dose-Response Relationship, Drug
Drug Synergism
Gene Expression Profiling
Gene Silencing
Humans
Leukemia, Myeloid, Acute
Nuclear Proteins
Protein Kinase Inhibitors
Protein Kinases
Protein-Tyrosine Kinases
Pyrazoles
Pyrimidines
Pyrimidinones
RNA Interference
RNA, Small Interfering
Signal Transduction
Tumor Stem Cell Assay

authors with profiles

Ryan Naylor