METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification.

METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification. Cell Stem Cell. 2018 02 01; 22(2):191-205.e9.

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subject areas

Adenosine
Animals
Carcinogenesis
Cell Differentiation
Cell Proliferation
Cell Survival
Down-Regulation
Gene Expression Regulation, Leukemic
HEK293 Cells
Hematopoietic Stem Cells
Humans
Leukemia, Myeloid, Acute
Methyltransferases
Mice, Inbred C57BL
Myeloid Cells
Neoplastic Stem Cells
Protein Biosynthesis
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-myb
Proto-Oncogene Proteins c-myc
RNA Stability
RNA, Messenger
Trans-Activators
Transcriptome
Up-Regulation

authors with profiles

Chuan He