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CUX1 is a haploinsufficient tumor suppressor gene on chromosome 7 frequently inactivated in acute myeloid leukemia.
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CUX1 is a haploinsufficient tumor suppressor gene on chromosome 7 frequently inactivated in acute myeloid leukemia.
CUX1 is a haploinsufficient tumor suppressor gene on chromosome 7 frequently inactivated in acute myeloid leukemia. Blood. 2013 Feb 07; 121(6):975-83.
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PubMed
subject areas
Acute Disease
Animals
Blotting, Western
Cell Line, Tumor
Chromosome Deletion
Chromosomes, Human, Pair 7
Drosophila melanogaster
Gene Expression Profiling
Haploinsufficiency
HeLa Cells
Homeodomain Proteins
Humans
Interleukin Receptor Common gamma Subunit
K562 Cells
Leukemia, Myeloid
Mice
Mice, Inbred NOD
Mice, Knockout
Mice, SCID
Nuclear Proteins
Repressor Proteins
Reverse Transcriptase Polymerase Chain Reaction
RNA Interference
Transcription Factors
Translocation, Genetic
Tumor Suppressor Proteins
U937 Cells
Xenograft Model Antitumor Assays
authors with profiles
Christopher D. Brown
Robert Grossman
John Cunningham
Megan Mcnerney