Item Type | Name |
Concept
|
Carcinoma, Squamous Cell
|
Concept
|
Cell Communication
|
Concept
|
Cell Count
|
Concept
|
Cell Differentiation
|
Concept
|
Cell Movement
|
Concept
|
Cell Nucleus
|
Concept
|
Carcinoma, Basal Cell
|
Concept
|
Carcinoma, Non-Small-Cell Lung
|
Concept
|
Cell Adhesion
|
Concept
|
Cell Cycle
|
Concept
|
Cell Transformation, Neoplastic
|
Concept
|
Dendritic Cells
|
Concept
|
Epithelial Cells
|
Concept
|
Mast Cells
|
Concept
|
Neoplastic Cells, Circulating
|
Concept
|
HeLa Cells
|
Concept
|
Receptors, Cell Surface
|
Concept
|
Stem Cells
|
Concept
|
Tumor Stem Cell Assay
|
Concept
|
Tumor Cells, Cultured
|
Concept
|
Cell Adhesion Molecules
|
Concept
|
3T3 Cells
|
Concept
|
Cell Proliferation
|
Concept
|
Embryonic Stem Cells
|
Concept
|
Single-Cell Analysis
|
Concept
|
Intercellular Signaling Peptides and Proteins
|
Concept
|
Primary Cell Culture
|
Concept
|
NIH 3T3 Cells
|
Concept
|
COS Cells
|
Concept
|
Cell Growth Processes
|
Concept
|
Cell Cycle Proteins
|
Concept
|
Active Transport, Cell Nucleus
|
Concept
|
Platelet Endothelial Cell Adhesion Molecule-1
|
Concept
|
HCT116 Cells
|
Concept
|
Stem Cell Niche
|
Concept
|
HEK293 Cells
|
Concept
|
Pancreatic Stellate Cells
|
Concept
|
Asymmetric Cell Division
|
Concept
|
Adaptor Proteins, Signal Transducing
|
Concept
|
Cell Transdifferentiation
|
Concept
|
Cell Death
|
Concept
|
Cell Hypoxia
|
Concept
|
Cell Polarity
|
Concept
|
Stromal Cells
|
Concept
|
Cell Lineage
|
Concept
|
MAP Kinase Signaling System
|
Concept
|
Extracellular Signal-Regulated MAP Kinases
|
Concept
|
Immunoglobulin J Recombination Signal Sequence-Binding Protein
|
Concept
|
Endothelial Cells
|
Concept
|
Cell Line, Tumor
|
Concept
|
Intracellular Signaling Peptides and Proteins
|
Concept
|
Cell Size
|
Concept
|
Host Cell Factor C1
|
Concept
|
Wnt Signaling Pathway
|
Concept
|
Cell Line
|
Concept
|
Cell Survival
|
Concept
|
Cells, Cultured
|
Concept
|
Neoplastic Stem Cells
|
Concept
|
Signal Transduction
|
Concept
|
Nuclear Export Signals
|
Concept
|
G2 Phase Cell Cycle Checkpoints
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Academic Article
|
Mouse and human CRKL is dosage sensitive for cardiac outflow tract formation.
|
Academic Article
|
Probing chromatin landscape reveals roles of endocardial TBX20 in septation.
|
Academic Article
|
Tbx20 Is Required in Mid-Gestation Cardiomyocytes and Plays a Central Role in Atrial Development.
|
Concept
|
Cell Plasticity
|
Concept
|
A549 Cells
|
Concept
|
Myeloid-Derived Suppressor Cells
|
Concept
|
COP9 Signalosome Complex
|
Concept
|
Madin Darby Canine Kidney Cells
|
Concept
|
MCF-7 Cells
|
Grant
|
Control of cardiomyocyte cell cycle by REST in heart failure and regeneration
|
Grant
|
Molecular and Cellular Mechanisms of Calcific Aortic Stenosis
|
Grant
|
TRANSCRIPTIONAL REGULATION OF ENDOCARDIAL DEVELOPMENT
|
Academic Article
|
Crk and Crkl Are Required in the Endocardial Lineage for Heart Valve Development.
|
Academic Article
|
A SOX17-PDGFB signaling axis regulates aortic root development.
|
Academic Article
|
Crk and Crkl have shared functions in neural crest cells for cardiac outflow tract septation and vascular smooth muscle differentiation.
|
Academic Article
|
The Spatiotemporal Expression of Notch1 and Numb and Their Functional Interaction during Cardiac Morphogenesis.
|
Academic Article
|
Control of sinus venous valve and sinoatrial node development by endocardial NOTCH1.
|
Academic Article
|
NF?B (Nuclear Factor ?-Light-Chain Enhancer of Activated B Cells) Activity Regulates Cell-Type-Specific and Context-Specific Susceptibility to Calcification in the Aortic Valve.
|
Academic Article
|
Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1.
|
Academic Article
|
Placental labyrinth formation in mice requires endothelial FLRT2/UNC5B signaling.
|
Academic Article
|
Emodin alleviates aortic valvular calcification by inhibiting the AKT/FOXO1 pathway.
|
Academic Article
|
Nfatc1's Role in Mammary Epithelial Morphogenesis and Basal Stem/progenitor Cell Self-renewal.
|
Academic Article
|
Sequential Ligand-Dependent Notch Signaling Activation Regulates Valve Primordium Formation and Morphogenesis.
|
Academic Article
|
Cranial neural crest deletion of VEGFa causes cleft palate with aberrant vascular and bone development.
|
Academic Article
|
BMP signaling mediated by constitutively active Activin type 1 receptor (ACVR1) results in ectopic bone formation localized to distal extremity joints.
|
Academic Article
|
Tbx20 acts upstream of Wnt signaling to regulate endocardial cushion formation and valve remodeling during mouse cardiogenesis.
|
Academic Article
|
Endocardial to myocardial notch-wnt-bmp axis regulates early heart valve development.
|
Academic Article
|
Astragaloside IV alleviates hypoxia/reoxygenation-induced neonatal rat cardiomyocyte injury via the protein kinase a pathway.
|
Academic Article
|
Analysis of the endocardial-to-mesenchymal transformation of heart valve development by collagen gel culture assay.
|
Academic Article
|
Cell autonomous requirement of endocardial Smad4 during atrioventricular cushion development in mouse embryos.
|
Academic Article
|
Spatial and temporal regulation of coronary vessel formation by calcineurin-NFAT signaling.
|
Academic Article
|
FOXP3 inhibits activation-induced NFAT2 expression in T cells thereby limiting effector cytokine expression.
|
Academic Article
|
A sandwiched ventricular explant assay to model mouse coronary angiogenesis ex vivo.
|
Academic Article
|
PROX1 Inhibits PDGF-B Expression to Prevent Myxomatous Degeneration of Heart Valves.
|
Academic Article
|
ß-Catenin regulates endocardial cushion growth by suppressing p21.
|
Academic Article
|
Prerequisite endocardial-mesenchymal transition for murine cardiac trabecular angiogenesis.
|
Academic Article
|
NFATc1 marks articular cartilage progenitors and negatively determines articular chondrocyte differentiation.
|
Academic Article
|
Perinatal angiogenesis from pre-existing coronary vessels via DLL4-NOTCH1 signalling.
|
Academic Article
|
NOTCH Signaling in Aortic Valve Development and Calcific Aortic Valve Disease.
|
Academic Article
|
Mutations in RNA Methyltransferase Gene NSUN5 Confer High Risk of Outflow Tract Malformation.
|
Academic Article
|
Robust integration of multiple single-cell RNA sequencing datasets using a single reference space.
|
Academic Article
|
Spatiotemporal Gene Coexpression and Regulation in Mouse Cardiomyocytes of Early Cardiac Morphogenesis.
|
Academic Article
|
FRS2a-dependent cell fate transition during endocardial cushion morphogenesis.
|
Academic Article
|
Endocardially Derived Macrophages Are Essential for Valvular Remodeling.
|
Academic Article
|
NOTCH maintains developmental cardiac gene network through WNT5A.
|
Academic Article
|
Myocardial ß-Catenin-BMP2 signaling promotes mesenchymal cell proliferation during endocardial cushion formation.
|
Academic Article
|
Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation.
|
Academic Article
|
Hemodynamic Forces Sculpt Developing Heart Valves through a KLF2-WNT9B Paracrine Signaling Axis.
|
Academic Article
|
BMP2 expression in the endocardial lineage is required for AV endocardial cushion maturation and remodeling.
|
Academic Article
|
Notch-Tnf signalling is required for development and homeostasis of arterial valves.
|
Academic Article
|
Developmental Mechanisms of Aortic Valve Malformation and Disease.
|
Academic Article
|
Cadherin-11 Overexpression Induces Extracellular Matrix Remodeling and Calcification in Mature Aortic Valves.
|
Academic Article
|
A series of robust genetic indicators for definitive identification of cardiomyocytes.
|
Academic Article
|
Low-intensity pulsed ultrasound prevents angiotensin II-induced aortic smooth muscle cell phenotypic switch via hampering miR-17-5p and enhancing PPAR-?.
|
Academic Article
|
Single-Cell Lineage Tracing Reveals that Oriented Cell Division Contributes to Trabecular Morphogenesis and Regional Specification.
|
Academic Article
|
GATA4 regulates Fgf16 to promote heart repair after injury.
|
Academic Article
|
Resident c-kit(+) cells in the heart are not cardiac stem cells.
|
Academic Article
|
Vertebrate Fidgetin Restrains Axonal Growth by Severing Labile Domains of Microtubules.
|
Academic Article
|
The cerebral cavernous malformation pathway controls cardiac development via regulation of endocardial MEKK3 signaling and KLF expression.
|
Academic Article
|
Hand2 is an essential regulator for two Notch-dependent functions within the embryonic endocardium.
|
Academic Article
|
Resident fibroblast lineages mediate pressure overload-induced cardiac fibrosis.
|
Academic Article
|
Epicardial calcineurin-NFAT signals through Smad2 to direct coronary smooth muscle cell and arterial wall development.
|
Academic Article
|
Accelerated coronary angiogenesis by vegfr1-knockout endocardial cells.
|
Academic Article
|
Brg1 governs a positive feedback circuit in the hair follicle for tissue regeneration and repair.
|
Academic Article
|
Endocardial cells form the coronary arteries by angiogenesis through myocardial-endocardial VEGF signaling.
|
Academic Article
|
The secondary heart field is a new site of calcineurin/Nfatc1 signaling for semilunar valve development.
|
Academic Article
|
Nfatc1 coordinates valve endocardial cell lineage development required for heart valve formation.
|
Academic Article
|
Chromatin regulation by Brg1 underlies heart muscle development and disease.
|
Academic Article
|
LC3-mediated fibronectin mRNA translation induces fibrosarcoma growth by increasing connective tissue growth factor.
|
Academic Article
|
Developmental expression of LC3alpha and beta: absence of fibronectin or autophagy phenotype in LC3beta knockout mice.
|
Academic Article
|
Protein inhibitor of activated STAT 3 modulates osteoclastogenesis by down-regulation of NFATc1 and osteoclast-associated receptor.
|
Academic Article
|
Regulation of the murine Nfatc1 gene by NFATc2.
|
Academic Article
|
Octamer proteins inhibit IL-4 gene transcription in normal human CD4 T cells.
|
Academic Article
|
Inner cell mass-specific expression of a cell adhesion molecule (PECAM-1/CD31) in the mouse blastocyst.
|
Academic Article
|
Induction of vascular smooth muscle cell tenascin-C gene expression by denatured type I collagen is dependent upon a beta3 integrin-mediated mitogen-activated protein kinase pathway and a 122-base pair promoter element.
|
Academic Article
|
Gene transfer in utero biologically engineers a patent ductus arteriosus in lambs by arresting fibronectin-dependent neointimal formation.
|
Academic Article
|
Tissue-specific and developmental regulation of transforming growth factor-beta1 expression in fetal lamb ductus arteriosus endothelial cells.
|
Academic Article
|
Microtubule involvement in translational regulation of fibronectin expression by light chain 3 of microtubule-associated protein 1 in vascular smooth muscle cells.
|
Academic Article
|
Nfatc1 directs the endocardial progenitor cells to make heart valve primordium.
|
Academic Article
|
Fog2 is critical for cardiac function and maintenance of coronary vasculature in the adult mouse heart.
|
Academic Article
|
NFATc1 identifies a population of proximal tubule cell progenitors.
|
Academic Article
|
Down syndrome critical region-1 is a transcriptional target of nuclear factor of activated T cells-c1 within the endocardium during heart development.
|
Academic Article
|
Characterization of Nfatc1 regulation identifies an enhancer required for gene expression that is specific to pro-valve endocardial cells in the developing heart.
|
Academic Article
|
Microtubule-associated protein 1 light chain 3 is a fibronectin mRNA-binding protein linked to mRNA translation in lamb vascular smooth muscle cells.
|
Academic Article
|
Activation of AcvR1-Mediated Signaling Results in Semilunar Valve Defects.
|
Academic Article
|
Notch signaling regulates Hey2 expression in a spatiotemporal dependent manner during cardiac morphogenesis and trabecular specification.
|
Grant
|
Molecular signaling in aortic valve development and congenital aortic valve defect
|
Grant
|
Developmental mechanisms of human congenital heart disease
|
Grant
|
Molecular aspects of CRKL in heart development and human disease
|
Grant
|
Single Cell RNA-seq to Identify Endocardial Ontogenic Factors for the Heart
|
Academic Article
|
Non-CpG methylation by DNMT3B facilitates REST binding and gene silencing in developing mouse hearts.
|
Academic Article
|
Chaperone Hsp47 Drives Malignant Growth and Invasion by Modulating an ECM Gene Network.
|
Academic Article
|
Lung Tumor Suppressor GPRC5A Binds EGFR and Restrains Its Effector Signaling.
|
Academic Article
|
Glycogen synthase kinase-3ß, NF-?B signaling, and tumorigenesis of human osteosarcoma.
|
Academic Article
|
Metabolic reprogramming of the tumour microenvironment.
|
Academic Article
|
beta-catenin interacts with and inhibits NF-kappa B in human colon and breast cancer.
|
Academic Article
|
Guidelines and definitions for research on epithelial-mesenchymal transition.
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Academic Article
|
Identification of Active Bronchioalveolar Stem Cells as the Cell of Origin in Lung Adenocarcinoma.
|
Academic Article
|
Twist promotes tumor metastasis in basal-like breast cancer by transcriptionally upregulating ROR1.
|
Academic Article
|
Inflammatory stimuli promote growth and invasion of pancreatic cancer cells through NF-?B pathway dependent repression of PP2Ac.
|
Academic Article
|
Upregulation of CXCR4 is essential for HER2-mediated tumor metastasis.
|
Academic Article
|
Loss of FBP1 by Snail-mediated repression provides metabolic advantages in basal-like breast cancer.
|
Academic Article
|
ITCH nuclear translocation and H1.2 polyubiquitination negatively regulate the DNA damage response.
|
Academic Article
|
Targeting the BRD4/FOXO3a/CDK6 axis sensitizes AKT inhibition in luminal breast cancer.
|
Academic Article
|
G9a interacts with Snail and is critical for Snail-mediated E-cadherin repression in human breast cancer.
|
Academic Article
|
Twist-mediated Epithelial-mesenchymal Transition Promotes Breast Tumor Cell Invasion via Inhibition of Hippo Pathway.
|
Academic Article
|
Novel targets of Akt, p21(Cipl/WAF1), and MDM2.
|
Academic Article
|
BRD4 modulates vulnerability of triple-negative breast cancer to targeting of integrin-dependent signaling pathways.
|
Academic Article
|
Epigenetic regulation of LSD1 during mammary carcinogenesis.
|
Academic Article
|
Metabolic rewiring in cancer-associated fibroblasts provides a niche for oncogenesis and metastatic dissemination.
|
Academic Article
|
CD151 represses mammary gland development by maintaining the niches of progenitor cells.
|
Academic Article
|
EGFR phosphorylates and inhibits lung tumor suppressor GPRC5A in lung cancer.
|
Academic Article
|
G9a is essential for EMT-mediated metastasis and maintenance of cancer stem cell-like characters in head and neck squamous cell carcinoma.
|
Academic Article
|
CD151-a3ß1 integrin complexes suppress ovarian tumor growth by repressing slug-mediated EMT and canonical Wnt signaling.
|
Academic Article
|
NF-?B represses retinoic acid receptor-mediated GPRC5A transactivation in lung epithelial cells to promote neoplasia.
|
Academic Article
|
Epithelial neoplasia coincides with exacerbated injury and fibrotic response in the lungs of Gprc5a-knockout mice following silica exposure.
|
Academic Article
|
Dysregulation of cellular signaling by HER2/neu in breast cancer.
|
Academic Article
|
Kinases meet at TSC.
|
Academic Article
|
HER-2/Neu signaling and therapeutic approaches in breast cancer.
|
Academic Article
|
Epithelial to mesenchymal transition (EMT) in human prostate cancer: lessons learned from ARCaP model.
|
Academic Article
|
The regulation of snail: on the ubiquitin edge.
|
Academic Article
|
Snail is critical for tumor growth and metastasis of ovarian carcinoma.
|
Academic Article
|
Metabolic reprogramming of cancer-associated fibroblasts by IDH3a downregulation.
|
Academic Article
|
Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3.
|
Academic Article
|
New insights of epithelial-mesenchymal transition in cancer metastasis.
|
Academic Article
|
Nanoparticle Delivery of miR-34a Eradicates Long-term-cultured Breast Cancer Stem Cells via Targeting C22ORF28 Directly.
|
Academic Article
|
A hypoxia-independent hypoxia-inducible factor-1 activation pathway induced by phosphatidylinositol-3 kinase/Akt in HER2 overexpressing cells.
|
Academic Article
|
Activation of ß-catenin and Akt pathways by Twist are critical for the maintenance of EMT associated cancer stem cell-like characters.
|
Academic Article
|
Epithelial-mesenchymal transition in breast cancer progression and metastasis.
|
Academic Article
|
Stabilization of PTGES by deubiquitinase USP9X promotes metastatic features of lung cancer via PGE2 signaling.
|
Academic Article
|
Snail determines the therapeutic response to mTOR kinase inhibitors by transcriptional repression of 4E-BP1.
|
Academic Article
|
Wnt, hedgehog and snail: sister pathways that control by GSK-3beta and beta-Trcp in the regulation of metastasis.
|
Academic Article
|
PP2A inhibitors arrest G2/M transition through JNK/Sp1- dependent down-regulation of CDK1 and autophagy-dependent up-regulation of p21.
|
Academic Article
|
The Context-Dependent Impact of Integrin-Associated CD151 and Other Tetraspanins on Cancer Development and Progression: A Class of Versatile Mediators of Cellular Function and Signaling, Tumorigenesis and Metastasis.
|
Academic Article
|
FBW7-Aurora B-p53 feedback loop regulates mitosis and cell growth.
|
Academic Article
|
The Role of Snail in EMT and Tumorigenesis.
|
Academic Article
|
Enhancement of Bik antitumor effect by Bik mutants.
|
Academic Article
|
Small C-terminal domain phosphatase enhances snail activity through dephosphorylation.
|
Academic Article
|
Snail: More than EMT.
|
Academic Article
|
Autocrine epiregulin activates EGFR pathway for lung metastasis via EMT in salivary adenoid cystic carcinoma.
|
Academic Article
|
IL6/STAT3 Signaling Orchestrates Premetastatic Niche Formation and Immunosuppressive Traits in Lung.
|
Academic Article
|
FH535, a ß-catenin pathway inhibitor, represses pancreatic cancer xenograft growth and angiogenesis.
|
Academic Article
|
Inflammation: a driving force speeds cancer metastasis.
|
Academic Article
|
Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition.
|
Academic Article
|
The Role of Stromal Components in Pancreatic Cancer Progression.
|
Academic Article
|
Inflammation fuels tumor progress and metastasis.
|
Academic Article
|
Twist-BRD4 complex: potential drug target for basal-like breast cancer.
|
Academic Article
|
Dysregulated Glutamate Transporter SLC1A1 Propels Cystine Uptake via Xc- for Glutathione Synthesis in Lung Cancer.
|
Academic Article
|
Disrupting the interaction of BRD4 with diacetylated Twist suppresses tumorigenesis in basal-like breast cancer.
|
Academic Article
|
Author Correction: Guidelines and definitions for research on epithelial-mesenchymal transition.
|
Academic Article
|
Hsp47 promotes cancer metastasis by enhancing collagen-dependent cancer cell-platelet interaction.
|
Academic Article
|
Stress-induced epinephrine enhances lactate dehydrogenase A and promotes breast cancer stem-like cells.
|
Academic Article
|
Phosphorylation/cytoplasmic localization of p21Cip1/WAF1 is associated with HER2/neu overexpression and provides a novel combination predictor for poor prognosis in breast cancer patients.
|
Academic Article
|
Stabilization of snail by NF-kappaB is required for inflammation-induced cell migration and invasion.
|
Academic Article
|
Dub3 inhibition suppresses breast cancer invasion and metastasis by promoting Snail1 degradation.
|
Academic Article
|
Autophagy regulation in the development and treatment of breast cancer.
|
Academic Article
|
Deletion of tetraspanin CD151 alters the Wnt oncogene-induced mammary tumorigenesis: A cell type-linked function and signaling.
|
Academic Article
|
The SNAG domain of Snail1 functions as a molecular hook for recruiting lysine-specific demethylase 1.
|
Academic Article
|
CD151-a3ß1 integrin complexes are prognostic markers of glioblastoma and cooperate with EGFR to drive tumor cell motility and invasion.
|
Academic Article
|
PTGES/PGE2 signaling links immunosuppression and lung metastasis in Gprc5a-knockout mouse model.
|
Academic Article
|
RORa suppresses breast tumor invasion by inducing SEMA3F expression.
|
Academic Article
|
PTEN loss induces epithelial--mesenchymal transition in human colon cancer cells.
|
Academic Article
|
Doxorubicin enhances Snail/LSD1-mediated PTEN suppression in a PARP1-dependent manner.
|
Academic Article
|
The deubiquitinase USP28 stabilizes LSD1 and confers stem-cell-like traits to breast cancer cells.
|
Academic Article
|
LIV-1 promotes prostate cancer epithelial-to-mesenchymal transition and metastasis through HB-EGF shedding and EGFR-mediated ERK signaling.
|
Academic Article
|
POMC maintains tumor-initiating properties of tumor tissue-derived long-term-cultured breast cancer stem cells.
|