| Item Type | Name |
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Concept
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Asparagine
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Concept
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Amino Acid Sequence
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Concept
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Anions
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Concept
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Aspartic Acid
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Concept
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Bacteriorhodopsins
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Concept
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Carbon Isotopes
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Concept
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Cross-Linking Reagents
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Concept
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Cysteine
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Concept
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Cytoplasm
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Concept
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Immunoglobulin Fab Fragments
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Concept
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Electrophoresis, Polyacrylamide Gel
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Concept
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Immunoglobulin Fragments
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Concept
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Spindle Apparatus
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Concept
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Halobacterium
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Concept
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Leishmania mexicana
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Concept
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Liposomes
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Concept
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Escherichia coli
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Concept
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Maleimides
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Concept
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Magnesium
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Concept
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Nitrates
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Concept
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Molecular Sequence Data
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Concept
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Monte Carlo Method
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Concept
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Mycobacterium tuberculosis
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Concept
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Ion Channels
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Concept
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Neutrophils
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Concept
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Oxygen Isotopes
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Concept
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Ligands
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Concept
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Oocytes
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Concept
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Gram-Negative Bacteria
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Concept
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Potassium Channels
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Concept
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Humans
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Concept
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Receptors, N-Methyl-D-Aspartate
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Concept
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Caenorhabditis elegans
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Concept
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Drug Design
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Concept
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Protein Engineering
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Concept
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Sodium Channels
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Concept
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Cryoelectron Microscopy
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Concept
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Water
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Concept
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Likelihood Functions
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Concept
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HIV Protease
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Concept
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Ion Channel Gating
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Concept
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Methanobacterium
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Concept
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Mutagenesis, Site-Directed
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Concept
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Microtubules
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Concept
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Proton Pumps
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Concept
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DNA, Complementary
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Concept
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Inflammation Mediators
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Concept
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Halobacterium salinarum
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Concept
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Kv1.3 Potassium Channel
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Concept
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Potassium Channel Blockers
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Concept
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Gap Junctions
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Concept
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Shaker Superfamily of Potassium Channels
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Concept
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Ether-A-Go-Go Potassium Channels
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Concept
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Amino Acid Substitution
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Concept
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Thermotoga maritima
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Concept
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Potassium Channels, Inwardly Rectifying
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Concept
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Databases, Protein
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Concept
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HEK293 Cells
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Concept
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Streptomyces lividans
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Concept
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Staphylococcus aureus
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Concept
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Streptomyces
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Concept
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Hydrophobic and Hydrophilic Interactions
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Concept
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Reproducibility of Results
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Concept
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Molecular Structure
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Concept
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HIV Protease Inhibitors
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Concept
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Halorhodopsins
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Concept
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Anion Transport Proteins
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Concept
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Microscopy, Atomic Force
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Concept
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Cation Transport Proteins
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Concept
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Caenorhabditis elegans Proteins
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Concept
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Kv1.2 Potassium Channel
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Concept
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Lipid Metabolism
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Concept
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Antibodies
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Concept
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Fluorescent Dyes
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Concept
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Haemophilus influenzae
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Concept
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Protons
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Concept
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Rubidium Radioisotopes
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Concept
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Spermatozoa
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Concept
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T-Lymphocytes
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Concept
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Cytokines
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Concept
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DNA Primers
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Concept
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Potassium Channels, Voltage-Gated
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Concept
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Potassium Channels, Calcium-Activated
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Concept
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Large-Conductance Calcium-Activated Potassium Channels
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Academic Article
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Structural dynamics of the Streptomyces lividans K+ channel (SKC1): secondary structure characterization from FTIR spectroscopy.
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Academic Article
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Three-dimensional architecture and gating mechanism of a K+ channel studied by EPR spectroscopy.
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Academic Article
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Structural dynamics of the Streptomyces lividans K+ channel (SKC1): oligomeric stoichiometry and stability.
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Academic Article
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Shedding light on voltage-dependent gating.
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Academic Article
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pH-dependent gating in the Streptomyces lividans K+ channel.
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Academic Article
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Gating currents in Shaker K+ channels. Implications for activation and inactivation models.
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Academic Article
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Molecular architecture of full-length KcsA: role of cytoplasmic domains in ion permeation and activation gating.
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Academic Article
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Structure of the KcsA channel intracellular gate in the open state.
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Academic Article
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Structural rearrangements underlying K+-channel activation gating.
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Academic Article
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EPR approaches to ion channel structure and function.
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Academic Article
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Open channel structure of MscL and the gating mechanism of mechanosensitive channels.
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Academic Article
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New structural perspectives on K(+) channel gating.
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Academic Article
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Structural biology. Force and voltage sensors in one structure.
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Academic Article
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Structure and mechanism in prokaryotic mechanosensitive channels.
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Academic Article
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Single channel studies of the phosphorylation of K+ channels in the squid giant axon. I. Steady-state conditions.
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Academic Article
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Calculation of rigid-body conformational changes using restraint-driven Cartesian transformations.
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Academic Article
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Molecular basis of gating charge immobilization in Shaker potassium channels.
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Academic Article
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Electrostatic interaction of a K+ channel RCK domain with charged membrane surfaces.
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Academic Article
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Voltage-dependent gating at the KcsA selectivity filter.
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Academic Article
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An optimized purification and reconstitution method for the MscS channel: strategies for spectroscopical analysis.
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Academic Article
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Phosphorylation affects voltage gating of the delayed rectifier K+ channel by electrostatic interactions.
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Academic Article
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Phosphorylation of K+ channels in the squid giant axon. A mechanistic analysis.
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Academic Article
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How to gate an ion channel: lessons from MthK.
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Academic Article
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Single channel studies of the phosphorylation of K+ channels in the squid giant axon. II. Nonstationary conditions.
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Academic Article
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Structural biology: A channel with a twist.
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Academic Article
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A molecular mechanism for proton-dependent gating in KcsA.
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Academic Article
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Molecular determinants of gating at the potassium-channel selectivity filter.
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Academic Article
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Design and characterization of a constitutively open KcsA.
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Academic Article
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Structural basis for the coupling between activation and inactivation gates in K(+) channels.
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Academic Article
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On the structural basis of modal gating behavior in K(+) channels.
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Academic Article
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A quantitative description of KcsA gating I: macroscopic currents.
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Academic Article
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A quantitative description of KcsA gating II: single-channel currents.
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Academic Article
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Mechanism of activation gating in the full-length KcsA K+ channel.
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Academic Article
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Molecular coupling in the human ether-a-go-go-related gene-1 (hERG1) K+ channel inactivation pathway.
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Academic Article
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A designer ligand specific for Kv1.3 channels from a scorpion neurotoxin-based library.
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Academic Article
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Structural refinement of membrane proteins by restrained molecular dynamics and solvent accessibility data.
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Academic Article
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Crystal structure of full-length KcsA in its closed conformation.
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Academic Article
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The activated state of a sodium channel voltage sensor in a membrane environment.
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Academic Article
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An emerging consensus on voltage-dependent gating from computational modeling and molecular dynamics simulations.
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Academic Article
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Spin-labeled amphotericin B: synthesis, characterization, biological and spectroscopic properties.
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Academic Article
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A multipoint hydrogen-bond network underlying KcsA C-type inactivation.
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Academic Article
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Modulation of K channels in dialyzed squid axons. ATP-mediated phosphorylation.
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Academic Article
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Thermodynamic coupling between activation and inactivation gating in potassium channels revealed by free energy molecular dynamics simulations.
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Academic Article
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Mechanism of Cd2+ coordination during slow inactivation in potassium channels.
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Academic Article
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Symmetry-constrained analysis of pulsed double electron-electron resonance (DEER) spectroscopy reveals the dynamic nature of the KcsA activation gate.
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Academic Article
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Gating of Shaker K+ channels: I. Ionic and gating currents.
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Academic Article
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S4 mutations alter gating currents of Shaker K channels.
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Academic Article
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Purification and reconstitution of functional Shaker K+ channels assayed with a light-driven voltage-control system.
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Academic Article
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Gating of Shaker K+ channels: II. The components of gating currents and a model of channel activation.
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Academic Article
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Reactions of cysteines substituted in the amphipathic N-terminal tail of a bacterial potassium channel with hydrophilic and hydrophobic maleimides.
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Academic Article
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The voltage sensor and the gate in ion channels.
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Academic Article
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Molecular architecture of the KvAP voltage-dependent K+ channel in a lipid bilayer.
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Academic Article
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Detection of the opening of the bundle crossing in KcsA with fluorescence lifetime spectroscopy reveals the existence of two gates for ion conduction.
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Academic Article
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Molecular driving forces determining potassium channel slow inactivation.
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Academic Article
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Structural dynamics of an isolated voltage-sensor domain in a lipid bilayer.
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Academic Article
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Structural mechanism of C-type inactivation in K(+) channels.
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Academic Article
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Chemical modification of squid axon K+ channel -SH groups with the organic mercurial compound p-hydroxymercuriphenylsulfonic acid (PHMPS).
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Academic Article
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Gating currents from a nonconducting mutant reveal open-closed conformations in Shaker K+ channels.
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Academic Article
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Expression, purification, and reconstitution of the voltage-sensing domain from Ci-VSP.
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Academic Article
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Recovery from slow inactivation in K+ channels is controlled by water molecules.
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Academic Article
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Importance of lipid-pore loop interface for potassium channel structure and function.
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Academic Article
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Structural basis of lipid-driven conformational transitions in the KvAP voltage-sensing domain.
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Academic Article
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Dynamics transitions at the outer vestibule of the KcsA potassium channel during gating.
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Academic Article
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Biochemical and structural analysis of the hyperpolarization-activated K(+) channel MVP.
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Academic Article
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Conformational dynamics at the inner gate of KcsA during activation.
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Academic Article
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Resting state of the human proton channel dimer in a lipid bilayer.
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Academic Article
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Multi-ion free energy landscapes underscore the microscopic mechanism of ion selectivity in the KcsA channel.
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Academic Article
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Instantaneous ion configurations in the K+ ion channel selectivity filter revealed by 2D IR spectroscopy.
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Academic Article
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Probing the Effects of Gating on the Ion Occupancy of the K+ Channel Selectivity Filter Using Two-Dimensional Infrared Spectroscopy.
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Academic Article
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Chemical substitutions in the selectivity filter of potassium channels do not rule out constricted-like conformations for C-type inactivation.
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Academic Article
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Towards a Structural View of Drug Binding to hERG K+ Channels.
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Academic Article
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Rapid constriction of the selectivity filter underlies C-type inactivation in the KcsA potassium channel.
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Academic Article
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De novo GRIN variants in NMDA receptor M2 channel pore-forming loop are associated with neurological diseases.
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Academic Article
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Electromechanical coupling in the hyperpolarization-activated K+ channel KAT1.
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Academic Article
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Mechanism of C-type inactivation in the hERG potassium channel.
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Academic Article
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Computational study of non-conductive selectivity filter conformations and C-type inactivation in a voltage-dependent potassium channel.
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Academic Article
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Mechanism of voltage sensing in Ca2+- and voltage-activated K+ (BK) channels.
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Academic Article
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Mechanism of voltage gating in the voltage-sensing phosphatase Ci-VSP.
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Concept
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ERG1 Potassium Channel
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Concept
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Cell Surface Display Techniques
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Concept
|
Voltage-Gated Sodium Channels
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Concept
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In Vitro Techniques
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Grant
|
MOLECULAR ARCHITECTURE OF POTASSIUM CHANNELS
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Academic Article
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Conformation-specific Synthetic Antibodies Discriminate Multiple Functional States of the Ion Channel CorA.
|